Genomics News and Research

RSS

Genomics is the study of the complete genetic material, including genes and their functions, of an organism.

Early genomic profiling improves cancer treatment outcomes

New real-world data from Providence, Illumina, and Microsoft Research reveals that Comprehensive Genomic Profiling (CGP), when done early in a cancer patient's diagnosis, leads to better personalized treatment and patient outcomes.

12 Nov 2024

MethylGPT unlocks DNA secrets for age and disease prediction

Researchers developed MethylGPT, a powerful transformer-based model that identifies DNA methylation patterns, enabling advanced age and disease prediction with clinical potential.

11 Nov 2024

Breakthrough research reveals how to target malignant DNA in aggressive cancers

Scientists have discovered a way to target elusive circular fragments of DNA that drive the survival of some of the most aggressive cancers, paving the way for future treatments.

9 Nov 2024

Genetic diagnosis solves medical mystery for 30 undiagnosed patients

An international team of researchers has provided a genetic diagnosis for 30 individuals whose condition was undiagnosed for years despite extensive clinical or genetic testing.

8 Nov 2024

MIT team creates efficient technique for identifying causal gene relationships

By studying changes in gene expression, researchers learn how cells function at a molecular level, which could help them understand the development of certain diseases.

8 Nov 2024

UAB team develops a combined score to predict cancer treatment success

In 1937, President Franklin Roosevelt signed the National Cancer Act, launching a nationwide effort to combat the disease.

7 Nov 2024

New antibiotic-resistant bacteria strain may be spreading across Asia

A virulent new strain of antibiotic-resistant bacteria that causes severe disease could be spreading widely across Asia - posing significant challenges to global public health, a new study reveals.

7 Nov 2024

Stanford researchers unveil the key role of extrachromosomal DNA in cancer

A trio of research papers from Stanford Medicine researchers and their international collaborators transforms scientists' understanding of how small DNA circles - until recently dismissed as inconsequential - are major drivers of many types of human cancers.

6 Nov 2024

Multitarget stool DNA test shows promise for early colorectal cancer detection

A recent prospective cross-sectional study in Thailand demonstrates that multitarget stool DNA testing is highly sensitive and specific for detecting colorectal cancer (CRC) among Thai individuals.

6 Nov 2024

Deciphering the mechanisms of immune response with probabilistic graphical networks

Over the past two decades, new technologies have helped scientists generate a vast amount of biological data. Large-scale experiments in genomics, transcriptomics, proteomics, and cytometry can produce enormous quantities of data from a given cellular or multicellular system.

5 Nov 2024

Multi-omics-based classification of gastrointestinal stromal tumors lays groundwork for precision treatment

A recent study offering a comprehensive view of the genome and transcriptome of gastrointestinal stromal tumors (GISTs) has introduced a new, multi-omics-based molecular classification of these tumors.

5 Nov 2024

Long sitting hours could accelerate aging in young adults

Between long commutes, Zoom-packed workdays and evenings of streaming and scrolling, millennials now spend more than 60 hours per week sitting, potentially boosting their heart disease risk and accelerating other signs of aging, according to new CU Boulder and University of California Riverside research.

4 Nov 2024

Iron and vitamin D reduce depression risk, while selenium and magnesium raise it

Researchers explore the causality between micronutrient intake and depression using Mendelian randomization.

4 Nov 2024

New imaging method could transform gene expression research

They say a picture is worth a thousand words. A new method, developed by University of Michigan researchers, creates images that are worth many gigabytes of data, which could revolutionize the way biologists study gene expression. Seq-Scope, developed by Jun Hee Lee, Ph.D., Hyun Min Kang, Ph.D., and their colleagues, was first described in Cell in 2021 as the first method to analyze gene expression at sub micrometer-scale spatial resolution.

1 Nov 2024

New therapeutic target overcomes ovarian cancer immunotherapy resistance

Researchers at the Icahn School of Medicine at Mount Sinai have discovered a way that ovarian cancer tumors manipulate their environment to resist immunotherapy and identified a drug target that could overcome that resistance.

1 Nov 2024

Mitochondrial genetics shed light on ALS Risk and protection

Using sequencing techniques, researchers associated 51 mutations in mitochondrial DNA with amyotrophic lateral sclerosis (ALS), an incurable degenerative neurological disorder that leads to muscle atrophy and paralysis.

31 Oct 2024

Fabric Genomics partners with Intermountain Children’s Health to enhance precision diagnosis of infants and children using whole genome sequencing from Broad Clinical Labs

Fabric Genomics, the leader in artificial intelligence (AI)-powered next generation sequencing interpretation, is announcing a new partnership with Intermountain Children’s Health to analyze the whole genomes of children sequenced by the Broad Clinical Labs to help speed diagnosis of kids who may have genetic diseases.

From Fabric Genomics 30 Oct 2024

descendantsDNA, Inc. engages Broad Clinical Labs and Fabric Genomics for genomic services to support human longevity

descendantsDNA, Inc. is pleased to announce a new agreement with Broad Clinical Labs (BCL) to advance human longevity through cutting-edge genomics.

From Fabric Genomics 30 Oct 2024

Machine learning reveals secrets of aging in flies and humans

Discoveries that impact lifespan and healthspan in fruit flies are usually tested in mice before being considered potentially relevant in humans, a process that is expensive and time intensive. A pioneering approach taken at the Buck Institute leapfrogs over that standard methodology.

30 Oct 2024

Research uncovers intrinsic factors influencing CAR-T cell success

Researchers from the Josep Carreras Leukaemia Research Institute have found that the efficacy of varni-cel, a CAR-T infusion product for B-ALL patients, is highly dependent on intrinsic features of the CAR-T cells themselves and their progression within the patient.

29 Oct 2024