Insulin Resistance News and Research

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Insulin Resistance is a condition in which the body does not respond to insulin properly. This is most common in Type II diabetes or associated with obesity, ketoacidosis, infection, and certain rare conditions. Diminished effectiveness of insulin in lowering blood glucose levels requiring 200 units or more of insulin per day to prevent hyperglycemia or ketosis.

Study links NAFLD with brain deterioration and identifies a potential therapeutic target

People with liver disease caused by eating too much sugar and fat could be at increased risk of developing serious neurological conditions like depression or dementia.

22 Dec 2022

Analysis finds more than 100 new genetic risk factors strongly linked to colorectal cancer

A comprehensive analysis of more than 100,000 colorectal cancer (CRC) cases, led by researchers at the Fred Hutchinson Cancer Center in Seattle and 200 scientific collaborators worldwide, has identified more than 100 new genetic risk factors strongly linked with the disease.

20 Dec 2022

Common type 2 diabetes drug requires the presence of GDF15 cytokine to present antidiabetic effects

Metformin, the most prescribed drug for treating diabetes mellitus, known as type 2 diabetes, requires the presence of the growth differentiation factor 15 (GDF15) —a protein whose expression increases in response to cellular stress— to present its antidiabetic effects.

16 Dec 2022

Revised guidelines for diabetes care

A recent Diabetes Care journal paper summarized the latest recommendations offered to people with diabetes to improve their health and well-being.

15 Dec 2022

Subcutaneous fat protects against brain inflammation in females

Females' propensity to deposit more fat in places like their hips, buttocks and the backs of their arms, so-called subcutaneous fat, is protective against brain inflammation, which can result in problems like dementia and stroke, at least until menopause, scientists report.

14 Dec 2022

Obesity and type 2 diabetes impair mRNA COVID vaccine efficacy in mouse model

In a recent study posted to bioRxiv*, researchers in the United States assessed the impact of metabolic diseases on coronavirus disease 2019 (COVID-19) vaccine immunogenicity in a mouse model.

13 Dec 2022

Gestational diabetes mellitus linked to early particulate matter exposure with high BMI

Researchers assess the impact of high BMI before pregnancy, coupled with exposure to different levels of PM, on the incidence of gestational diabetes.

6 Dec 2022

Honey improves key measures of health, including blood sugar and cholesterol levels

Researchers look to better understand the impact of honey on mitigating certain cardiometabolic risk factors.

20 Nov 2022

Why we should all eat Kimchi and other Korean fermented foods

A recent study reviews various traditional Korean fermented foods for their various health benefits.

20 Nov 2022

Ketogenic diet may show more promising results than Mediterranean diets in short-term type 2 diabetes management

Researchers evaluated the short-term impact of the very-low-calorie ketogenic diet (VLCKD) and Mediterranean diet (MD) on the gut microbiota (GM) of obese patients with new-onset type II diabetes (T2DM).

15 Nov 2022

What is the association between diabetes and SARS-CoV-2 infections?

Researchers explored whether severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can expedite or trigger the development of diabetes mellitus (DM).

15 Nov 2022

Exercise program improves insulin action in the brain

If the brain no longer responds correctly to the hormone insulin (insulin resistance), this also has a negative effect on the metabolism in the body and the regulation of eating behavior.

7 Nov 2022

Exercising in the afternoon or at night best for blood sugar control

The impact of breaks in sedentary time and timing of physical activity with insulin resistance and liver fat content.

6 Nov 2022

Environmental toxicants contribute to obesity and metabolic disease

In a recent study published in the Current Opinion in Pharmacology journal, researchers assessed the impact of environmental toxicants and brown adipose tissue (BAT) on obesity and metabolic disorders.

4 Nov 2022

NIH awards $2.1 million grant to UMass Amherst epidemiologist

A University of Massachusetts Amherst epidemiologist has been awarded a five-year, $2.1 million grant from the National Institutes of Health (NIH) to continue research that aims to understand how physical and mental health during pregnancy can help predict cardiovascular and mental health disorders in middle age.

2 Nov 2022

Does maternal insulin tolerance during pregnancy influence child adiposity?

Researchers explore the association between maternal insulin resistance with fetal fat deposition.

27 Oct 2022

Study finds sexual dimorphism in the development of vascular insulin resistance induced by obesogenic lifestyle

A new study from the University of Missouri School of Medicine is the first evidence in humans that short-term lifestyle changes can disrupt the response to insulin of blood vessels. It's also the first study to show men and women react differently to these changes.

27 Oct 2022