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UCLA researchers decode the muscle mechanics behind blinking

A blink of an eye seems natural and instantaneous, but is it? Without a functioning eyelid, the eye can become dry, irritated and eventually lose the ability to see clearly.

8 Aug 2025

New insights into how MYOD controls muscle repair and regeneration

For more than 30 years, scientists have studied how the myogenic determination gene number 1 (MYOD) protein binds DNA to modify the gene expression of muscle stem cells.

8 Aug 2025

Exploring the genetic and clinical landscape of clubfoot

A new publication offers an extensive examination of clubfoot, a congenital deformity known as congenital talipes equinovarus (CTEV), affecting about 0.3% of all live births.

8 Aug 2025

CRISPR screening uncovers microproteins involved in fat storage

The obesity rate has more than doubled in the last 30 years, affecting more than one billion people worldwide.

7 Aug 2025

How too much screen time affects kids’ heart health and what can reduce the risk

A large Danish cohort study found that higher screen time in childhood and adolescence is linked to worse cardiometabolic health, with shorter sleep amplifying the risk. Blood metabolomics revealed a signature of high screen time, and in teens, it was tied to higher predicted cardiovascular disease risk.

7 Aug 2025

Targeted microglia replacement shows promise against fatal neurodegenerative conditions

Tay-Sachs and Sandhoff diseases, genetic disorders affecting the brain, have no effective treatment and are typically fatal within the first years of life.

6 Aug 2025

Heart cells adapt and stretch to shape a healthy beating heart

Researchers at the Francis Crick Institute have discovered that the heart's own contractions trigger biological signals that guide the formation of a functional beating heart.

6 Aug 2025

Immune aging drives the progression of type 2 diabetes

Type 2 diabetes (T2D) is a global metabolic epidemic driven by insulin resistance (IR), chronic inflammation, and β-cell failure.

6 Aug 2025

Weight loss with ozempic may weaken muscles even when size remains stable

As use of the popular anti-diabetic and weight-loss drug Ozempic skyrockets, so have concerns about the medication's side effects.

5 Aug 2025

Breakthrough study reveals potential treatment path for ALS

Amyotrophic lateral sclerosis (ALS), known as Lou Gehrig's disease, is an incurable neurological disorder affecting motor neurons-nerve cells in the brain and spinal cord that control voluntary muscle movement and breathing.

5 Aug 2025

Metabolite patterns reveal potential for COPD population screening

The possibility of having a tool that facilitates population screening for Chronic Obstructive Pulmonary Disease (COPD) is getting closer.

5 Aug 2025

Targeted botox delivery shows promise for treating jaw disorder

Temporomandibular disorder (TMD) limits jaw function and is so painful that it lessens the quality of life.

4 Aug 2025

Weight loss doubles when eating minimally processed foods over ultra-processed alternatives

When given nutritionally matched diets, participants lost twice as much weight eating minimally processed foods compared to ultra-processed foods, suggesting that cutting down on processing could help to sustain a healthy weight long term, finds a new clinical trial led by researchers at UCL and UCLH.

4 Aug 2025

Editorial emphasizes the critical role of heart-lung interactions in pulmonary vascular disease

A new editorial published in Comprehensive Physiology underscores the critical importance of understanding heart-lung interactions in pulmonary vascular disease (PVD).

4 Aug 2025

Creatine in your diet may benefit your digestive system

Findings suggest dietary creatine from meat may alleviate chronic constipation, with stronger effects observed in men and those without certain health issues.

4 Aug 2025

New Swiss study probes lingering fatigue after Legionnaires' disease

Researchers in Switzerland launched the LongLEGIO study to compare the long-term health impacts of Legionnaires’ disease and other bacterial pneumonias. Baseline data reveal key differences in comorbidities and quality of life between the groups, with follow-up underway.

4 Aug 2025

Metformin’s blood sugar control starts in the brain, not just the liver, study finds

Low, clinically relevant doses of metformin lower blood glucose by inhibiting the Rap1 protein in specific neurons of the hypothalamus, revealing a brain-first mechanism. This action is essential for metformin’s effect at therapeutic doses and highlights new directions for diabetes treatment.

3 Aug 2025