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Amyloid immunotherapy for early Alzheimer's: Promising but fraught with challenges

Researchers highlighted the complexities of using amyloid immunotherapy for early Alzheimer's disease, discussing its clinical benefits, challenges, and broader health implications. Despite some positive results, concerns over adverse effects, trial biases, and cost hinder widespread adoption.

7 Aug 2024

New stem cell therapy for heart failure undergoing U.S. clinical trials

A new stem cell therapy for heart failure is being tested in patients at the University of Louisville and UofL Health.

7 Aug 2024

From discovery to approval: Vorasidenib approved by FDA for treatment of IDH-mutant gliomas

A new drug for treatment of a type of brain cancer, called IDH-mutant low-grade glioma, was approved Aug. 6 by the U.S. Food and Drug Administration (FDA).

7 Aug 2024

FDA approves vorasidenib for Grade 2 gliomas with IDH mutations

Vorasidenib has been approved by the U.S. Food and Drug Administration (FDA) for patients with Grade 2 gliomas with IDH1 or IDH2 mutations.

6 Aug 2024

Omega-3 fatty acids show potential in protecting brain health in older adults

Researchers assess the role of ω-3 polyunsaturated fatty acids (PUFAs) in reducing white matter lesion accumulation and neuronal integrity degeneration.

6 Aug 2024

Cambridge experts question efficacy and practicality of new amyloid immunotherapy drugs

Cambridge researchers have cast doubt on whether new amyloid immunotherapy drugs will have the desired effect of significantly reducing the impact of Alzheimer's disease.

6 Aug 2024

Dopamine treatment can reduce Alzheimer's plaques and improve memory

A new way to combat Alzheimer's disease has been discovered by Takaomi Saido and his team at the RIKEN Center for Brain Science (CBS) in Japan.

6 Aug 2024

Nudges seem to have no effect in motivating people to get vaccinated

One popular strategy to motivate people to get vaccinated is the nudge - a message designed to take advantage of human tendencies to conform to social norms, seek to protect loved ones or community, and to prefer treatments with high efficacy rates.

6 Aug 2024

Cannabigerol shows promise in reducing anxiety and stress, study finds

Whether the phytocannabinoid cannabigerol impacted mood, stress, and anxiety and caused any related adverse effects of cognitive or motor impairment.

5 Aug 2024

New lab technique captures aging effects in Alzheimer's disease development

Researchers at Washington University School of Medicine in St. Louis have developed a way to capture the effects of aging in the development of Alzheimer's disease.

1 Aug 2024

Fish oil may benefit older adults with genetic Alzheimer's risk

A clinical trial at Oregon Health & Science University suggests that a subset of older adults with a genetic predisposition to Alzheimer's disease may benefit from fish oil supplements.

1 Aug 2024

Study finds cannabigerol effectively reduces anxiety, boosts memory recall

A lesser-known cannabinoid that is gaining in popularity Cannabigerol (CBG) effectively reduced anxiety in a clinical trial without the intoxication typically associated with whole plant cannabis.

31 Jul 2024

Probiotic LGG reduces necrotizing enterocolitis risk in preterm infants

The strain-specific effects of Lactobacillus rhamnosus GG (LGG) in preterm infants through a systematic review and meta-analysis of randomized controlled trials (RCTs) and non-RCTs.

31 Jul 2024

Hydrogen-rich gas inhalation reduces exercise-induced fatigue and enhances performance

A new study published in the International Journal of Sports Medicine, Inhalation of hydrogen-rich gas before acute exercise alleviates exercise fatigue, has found a possible novel intervention for exercise-induced fatigue.

30 Jul 2024

Low-dose aspirin does not affect the progression of age-related hearing loss

The effect of daily low-dose aspirin versus placebo on the progression of age-related hearing loss in healthy older adults.

30 Jul 2024

Study reveals curcumin’s antidepressant effects in obese type 2 diabetes patients

A randomized clinical trial (RCT) to investigate the effectiveness of curcumin in lowering depression among obese individuals with diabetes mellitus type 2 (T2DM).

30 Jul 2024

Weight loss guaranteed! But what impact on your diet? A review of GLP-1 and GIP/GLP-1 interventions

Researchers reviewed studies on dietary impacts of GLP-1 and GIP/GLP-1 receptor agonists in obesity and T2D patients, finding significant caloric reduction but limited evaluation of dietary composition.

29 Jul 2024

Lettuce found comparable to dock leaf for nettle sting relief

Rubbing a lettuce leaf on a nettle sting to ease the associated discomfort may be just as good as using the age-old folk remedy of a dock leaf, suggest the results of a small comparative study, published online in Emergency Medicine Journal.

29 Jul 2024

Neuroscientists discover a key piece of the placebo effect puzzle

The placebo effect is very real. This we've known for decades, as seen in real-life observations and the best double-blinded randomized clinical trials researchers have devised for many diseases and conditions, especially pain.

24 Jul 2024

Comprehensive dataset from A4 study yields key insights about Alzheimer's disease

Data from the Anti-Amyloid Treatment in Asymptomatic Alzheimer's (A4) study, the first and largest clinical trial of pre-symptomatic Alzheimer's disease, is now widely available to researchers studying the condition.

24 Jul 2024