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New oral drug safely lowers triglycerides and other blood lipids in Phase 1 trial

In a Phase 1 clinical study, researchers led by EPFL and their partners report that a new liver- and gut-targeted oral drug can safely lower triglycerides and other blood lipids.

16 Jan 2026

Incretin-based diabetes drugs show potential protective effects against dementia

A large McGill University study has found that two classes of medications commonly prescribed for Type 2 diabetes, both incretin-based, are associated with a reduced risk of dementia.

15 Jan 2026

Thermogenic beige fat protects blood vessels from hypertension

Obesity causes hypertension. Hypertension causes cardiovascular disease. And cardiovascular disease is the leading cause of death worldwide.

15 Jan 2026

Gut bacteria compound during pregnancy protects offspring from fatty liver disease

Children born to mothers who consume a high-fat, high-sugar diet during pregnancy and breastfeeding face a higher risk of developing fatty liver disease later in life.

14 Jan 2026

Scientists uncover promising therapeutic target for autoimmune disease affecting the brain

Scientists have identified a promising target for treatment of a devasting autoimmune disease affecting the brain.

14 Jan 2026

New chemistry revives neurokinin-1 receptor as depression treatment target

For decades, scientists have investigated the neurokinin-1 receptor (NK1R) as a potential target for treating major depressive disorder.

14 Jan 2026

Bariatric surgery reshapes body fat and muscle more than GLP-1 drugs

Bariatric surgery and GLP-1 treatments reshape body composition differently, emphasizing the importance of sex and treatment choice in muscle preservation.

14 Jan 2026

Most patients regain lost weight within two years of stopping obesity drugs

Weight management medications show limited long-term effects, with rapid weight regain post-treatment, emphasizing the need for sustainable obesity strategies.

13 Jan 2026

New publication describes the chemical journey of non-hormonal male birth control pill

A newly published manuscript authored by Dr. Gunda Georg, YourChoice Therapeutics and Columbia University Medical Center describes the chemical journey of YCT-529, a non-hormonal male birth control pill, and the promising molecular science behind it.

12 Jan 2026

Why adherence determines weight loss success with semaglutide

Researchers examine how the effectiveness of weight-loss medications may depend on the patient adherence.

12 Jan 2026

Study uncovers a neural brake that limits motivation during unpleasant situations

Most of us know the feeling: maybe it is making a difficult phone call, starting a report you fear will be criticized, or preparing a presentation that's stressful just to think about.

9 Jan 2026

Study reveals how tuberculosis exploits immune defenses to promote infection

Scientists have made a discovery that helps explain why humans and animals are so susceptible to contracting tuberculosis(TB) – and it involves the bacteria harnessing part of the immune system meant to protect against infection.

9 Jan 2026

Weight loss drugs and surgery improve body composition in patients with obesity

Both the new weight loss drugs and bariatric (weight loss) surgery improve body composition in patients with obesity by inducing a moderate loss of fat-free mass (including lean muscle) along with a substantial reduction in fat, researchers at Vanderbilt Health have found.

9 Jan 2026

Global analysis shows widespread eligibility for GLP-1 weight management drugs

The worldwide prevalence of obesity has more than doubled in the last three decades, bringing with it an increase in weight-related diseases like diabetes, cardiovascular disease, and cancers.

8 Jan 2026

$Neural pain pathways found to play crucial role in bone fracture healing$

Neural pain pathways found to play crucial role in bone fracture healing

When a house catches on fire, we assume that a smoke alarm inside will serve one purpose and one purpose only: warn the occupants of danger.

8 Jan 2026

Recent advances in CAR-NK cell therapy could revolutionze cancer treatment

Cell-based immunotherapies have transformed cancer treatment, yet their widespread use remains constrained by safety risks, manufacturing complexity, and limited effectiveness against solid tumors.

8 Jan 2026

Researchers develop enhanced antibodies to unleash the immune system against cancer

Researchers at the University of Southampton have developed a promising new way to bolster the body's immune system response to cancer.

8 Jan 2026

UC Davis team creates new class of serotonin-effecting drugs

UC Davis researchers have developed a new method that uses light to transform amino acids - the building blocks of proteins - into molecules that are similar in structure to psychedelics and mimic their interaction with the brain.

8 Jan 2026

Study highlights prevalence of GLP-1/GIP medication use for weight loss in UK

In early 2025, around 4.9 million British adults - almost one in ten - are estimated to have recently used, or expressed interest in using, glucagon-like peptide-1 (GLP-1) or dual GLP-1/glucose-dependent insulinotropic polypeptide (GIP) receptor agonist medications to support weight loss. The findings, which are based on a nationally representative household survey of 5,260 British adults, are published in BMC Medicine.

8 Jan 2026

Stimulating immune cells could offer new treatment for nerve injury pain

Researchers at The University of Texas MD Anderson Cancer Center have discovered that targeting a specific immune process could help improve recovery after nerve injury and reduce chronic pain.

7 Jan 2026

Receptor News and Research

New oral drug safely lowers triglycerides and other blood lipids in Phase 1 trial

Incretin-based diabetes drugs show potential protective effects against dementia

Thermogenic beige fat protects blood vessels from hypertension

Gut bacteria compound during pregnancy protects offspring from fatty liver disease

Scientists uncover promising therapeutic target for autoimmune disease affecting the brain

New chemistry revives neurokinin-1 receptor as depression treatment target

Bariatric surgery reshapes body fat and muscle more than GLP-1 drugs

Most patients regain lost weight within two years of stopping obesity drugs

New publication describes the chemical journey of non-hormonal male birth control pill

Why adherence determines weight loss success with semaglutide

Study uncovers a neural brake that limits motivation during unpleasant situations

Study reveals how tuberculosis exploits immune defenses to promote infection

Weight loss drugs and surgery improve body composition in patients with obesity

Global analysis shows widespread eligibility for GLP-1 weight management drugs

Neural pain pathways found to play crucial role in bone fracture healing

Recent advances in CAR-NK cell therapy could revolutionze cancer treatment

Researchers develop enhanced antibodies to unleash the immune system against cancer

UC Davis team creates new class of serotonin-effecting drugs

Study highlights prevalence of GLP-1/GIP medication use for weight loss in UK

Stimulating immune cells could offer new treatment for nerve injury pain

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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