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Gut microbiome metabolite butyrate relieves chronic jaw joint pain

Temporomandibular joint (TMJ) pain is associated with disrupted gut microbiome metabolites. Researchers reveal that butyrate, administered as tributyrin, alleviates pain by restoring histone acetylation and reversing gene regulatory changes in the brain.

18 May 2026

Body weight and genes directly alter gut microbiota composition

Your body weight and genes influence the types of bacteria you have in your gut. In turn, this appears to affect the risk of developing conditions such as coeliac disease and haemorrhoids.

18 May 2026

International trial proves AI can design gold-standard cancer treatment plans

An AI technology is effective at planning the delivery of life-saving radiotherapy for cervical cancer and prostate cancer, according to results from a large international trial led by researchers at University College London (UCL) and the London School of Hygiene & Tropical Medicine (LSHTM).

18 May 2026

Vaginal birth after cesarean more common at Black-serving hospitals

Low-risk patients at predominantly Black-serving hospitals (BSH) who previously gave birth through Cesareans are likelier to attempt and successfully deliver vaginally in a subsequent pregnancy than they are at hospitals treating few Black patients, new UCLA-led research finds.

17 May 2026

Fewer radiotherapy sessions for prostate cancer show minimal side effects

Two larger doses of radiotherapy for prostate cancer cause no additional side effects compared to the standard five doses of radiotherapy, according to results presented at the Congress of the European Society for Radiotherapy and Oncology (ESTRO 2026).

17 May 2026

Prenatal chemical mixtures may influence fetal growth and placental health

Common environmental chemicals could affect birthweight and placental function, according to a new study published in Environmental Science & Technology and led by the Barcelona Institute for Global Health (ISGlobal), a centre supported by "la Caixa" Foundation. Conducted within the Barcelona Life Study Cohort (BiSC), the research underscores the importance of considering real-life exposure to complex chemical mixtures and highlights the role of angiogenic biomarkers in linking these exposures to fetal development.

17 May 2026

New guidelines for identifying and treating high-risk IEC-HS patients

Chimeric antigen receptor T-cell (CAR-T) therapy has revolutionized the treatment of hematologic malignancies, offering durable responses for patients with otherwise refractory disease. However, its clinical success is accompanied by a spectrum of immune-related toxicities, which remain a major challenge in practice.

15 May 2026

New CRISPR breakthrough promises more affordable disease diagnostics

A team of engineers at the University of Florida has developed a new form of CRISPR technology that could make diagnostics and treatments safer, more precise, and more affordable, while opening the door to entirely new ways of controlling disease.

15 May 2026

Rocket Science Health validates targeted olfactory-cleft deposition in non-human primates ahead of the 4th Nasal Formulation & Delivery Summit

As the pace of modern drug discovery accelerates, the industry is increasingly recognizing that a breakthrough molecule is only as effective as its ability to reach the target site.

From Hanson Wade Group - 4th Nasal Formulation & Delivery Summit 15 May 2026

Maternal occupations linked to increased autism diagnosis odds

Findings indicate that certain maternal jobs are associated with increased autism odds in children, highlighting the importance of prenatal occupational health.

15 May 2026

Asymptomatic transmission plays a prominent role in mpox infection patterns

A Kaiser Permanente study of nearly 8,000 men shows that in mid- to late 2024, mpox was far more common among men who have sex with men than previously thought. Individuals without symptoms accounted for most infections and likely played a prominent role in transmission, contrary to prior assumptions that people had to be symptomatic to spread the disease.

15 May 2026

Researchers develop pH and redox-sensitive systems to reduce immunotherapy toxicity

Although cancer immunotherapy has transformed treatment by harnessing the immune system to eliminate tumors, only a small subset of patients benefit. Many solid tumors remain "cold," characterized by poor immune cell infiltration and resistance to immune checkpoint blockade (ICB).

15 May 2026

New FUSILLI tool improves gene fusion detection in pediatric leukemia

Researchers have introduced a novel diagnostics method that can more sensitively detect gene fusions in B-cell acute lymphoblastic leukemia (B-ALL), the most common type of pediatric cancer, compared to other publicly available fusion detection algorithms.

15 May 2026

New technology reveals how RNA shapes influence protein production and stability

Researchers from A*STAR Genome Institute of Singapore (A*STAR GIS) have developed a new method, called 'sm-PORE-cupine', to study individual RNA molecules and reveal how their structures influence gene regulation, a fundamental process that affects how cells function in health and disease.

15 May 2026

Stanford scientists map the molecular diversity of different global populations

Researchers at the Stanford School of Medicine have found that ethnicity and geography may influence human molecular makeup - from metabolism and immunity to gut microbiota and biological aging.

14 May 2026

Retinal stimulation via contact lenses effective as antidepressants in mice

Materials scientists have designed brain-stimulating contact lenses that are as effective as Prozac at treating depression in mice. The soft, transparent contact lenses have in-built electrodes that deliver mild electrical signals to the brain via the retina to stimulate specific brain regions associated with depression.

14 May 2026

Thyroid hormone profiles provide critical prognostic clues for patients facing liver failure

Early and accurate prognostic assessment is crucial to prevent disease progression in liver failure. Thyroid hormones (THs), particularly triiodothyronine (T3), are key metabolic regulators and play an important role in liver regeneration. Liver failure is frequently complicated by non‑thyroidal illness syndrome (NTIS), characterized by low T3 with normal or slightly elevated TSH and T4.

14 May 2026

Scientists develop a superior diagnostic tool to spot hidden gene fusions in pediatric cancer

Researchers have introduced a novel diagnostic method that can more sensitively detect gene fusions in B-cell acute lymphoblastic leukemia (B-ALL), the most common type of pediatric cancer, compared to other publicly available fusion detection algorithms.

14 May 2026

New tool estimates the risk of driving under the influence of medicine

Researchers from the SABIEN group at the ITACA Institute of the Universitat Politècnica de València (UPV), in collaboration with several partner institutions, have developed a new tool to estimate the risk of using medicines while driving.

14 May 2026

Smart technology meets wound care to combat dangerous diabetic ulcers

"Diabetic ulcers," which occur in patients with diabetes, are dangerous complications that can lead to amputation if the treatment window is missed. A joint research team has developed a "smart dressing patch" that can monitor wound conditions in real time.

14 May 2026