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New SARS-Cov-2 mutations could arise during chronic infection, say scientists

SARS-CoV-2 mutations similar to those in the B1.1.7 UK variant could arise in cases of chronic infection, where treatment over an extended period can provide the virus multiple opportunities to evolve, say scientists.

7 Feb 2021

Army scientists evaluate three nonhuman primate models of SARS-CoV-2 airborne infection

Army scientists evaluated three nonhuman primate species as potential models of SARS-CoV-2 airborne infection, according to results published online this week in PLOS ONE.

5 Feb 2021

ZyCoV-D SARS-CoV-2 DNA vaccine shows robust immunogenicity and protective efficacy in Rhesus macaquesys

A team of scientists from India has recently tested the efficacy and immunogenicity of two different concentrations of a plasmid DNA-based vaccine candidate ZyCoV-D. The findings reveal that the vaccine candidate administered via Needle Free Injection System (NFIS) can significantly induce the production of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein-specific IgG and neutralizing antibodies for a prolonged period.

4 Feb 2021

Hematological findings in Amazonian patients with COVID-19

To discriminate between patients with severe and non-severe COVID-19 quickly, researchers from Peru looked for prognostic signatures in the blood samples of COVID-19 patients. Virgilio E. Failoc-Rojas et al. examined laboratory results and clinical prognosis of COVID-19 patients from a hospital in the Peruvian Amazon.

3 Feb 2021

New gene-based vaccine strategy receives grant from the Bill & Melinda Gates Foundation

The AAVCOVID vaccine program, a novel gene-based vaccine strategy that utilizes an adeno-associated virus (AAV) vector, was granted an award for up to $2.1 million from the Bill & Melinda Gates Foundation.

29 Jan 2021

Mutations in the SARS-CoV-2 receptor-binding domain analyzed

Using more than 100,000 virus genome sequences uploaded in the GISAID database, researchers found around 9,000 mutations in the virus spike protein RBD.

26 Jan 2021

Researchers develop method for presymptomatic COVID-19 detection

An encouraging new study by researchers at University College London, UK, reports the potential of a form of COVID-19 testing which can detect presymptomatic cases.

26 Jan 2021

New SARS-CoV-2 variant must be curbed to protect UK health services, warn experts

A new research project called REACT-1 – launched by researchers at the Imperial College London, Imperial College Healthcare NHS Trust, and Ipsos MORI – has aimed to better understand the dynamics of SARS-CoV-2’s viral spread across the UK.

26 Jan 2021

Probiotics as adjuvant therapy for COVID-19 patients

In a recent review published in the Journal of Diabetes & Metabolic Syndrome: Clinical Research & Reviews, Luigi Santacroce and Francesco Inchingolo et al. address the many factors such as dysbiosis (imbalance in the microbiota) that could influence the SARS-CoV-2 infection course.

25 Jan 2021

UC researchers test new combination therapy for head and neck cancer in animal models

Head and neck cancer is the sixth most common cancer worldwide, and while effective treatments exist, sadly, the cancer often returns.

22 Jan 2021

SU2C announces $3.25 million in grants to find new treatments for head and neck cancers

Stand Up To Cancer today announced $3.25 million in grants from four national nonprofits to fund research to find new treatments for head and neck cancers, which are newly diagnosed in about 65,000 Americans every year.

21 Jan 2021

New SARS-CoV-2 strain detected in Southern California, USA

By analyzing throat and nose swabs from patients in Southern California, researchers detected a new SARS-CoV-2 strain with mutations in the spike protein. This major finding may explain a surge in the number of cases in the region.

21 Jan 2021

How does SARS-CoV-2 infect brain cells?

Researchers from the University of California San Francisco, Gladstone Institutes in the USA, and The Aga Khan University in Pakistan investigated if human neural cells can be infected by SARS-CoV-2.

20 Jan 2021

Patients fend for themselves to access highly touted covid antibody treatments

By the time he tested positive for covid-19 on Jan. 12, Gary Herritz was feeling pretty sick. He suspects he was infected a week earlier, during a medical appointment in which he saw health workers who were wearing masks beneath their noses or who had removed them entirely.

20 Jan 2021

Gene-cutting system may play second role as a genetic dimmer switch

In a series of experiments with laboratory-cultured bacteria, Johns Hopkins scientists have found evidence that there is a second role for the widely used gene-cutting system CRISPR-Cas9 -- as a genetic dimmer switch for CRISPR-Cas9 genes.

19 Jan 2021

About 60 percent of SARS-CoV-2 cases in England tied to new variant by the end of December

One new SARS-CoV-2 variant of concern, called 202012/01, started to spread in England in late October. A new study published on the pre-print server medRxiv found that 60 percent of daily COVID-19 cases screened by the Alderley Park Lighthouse Labs were tied to 202012/01, also known as lineage B.1.1.7 or 20B/501Y.V1. This suggests a rapid spread of the new variant across the country.

18 Jan 2021

Throat News and Research

New SARS-Cov-2 mutations could arise during chronic infection, say scientists

Army scientists evaluate three nonhuman primate models of SARS-CoV-2 airborne infection

ZyCoV-D SARS-CoV-2 DNA vaccine shows robust immunogenicity and protective efficacy in Rhesus macaquesys

Hematological findings in Amazonian patients with COVID-19

New gene-based vaccine strategy receives grant from the Bill & Melinda Gates Foundation

Mutations in the SARS-CoV-2 receptor-binding domain analyzed

Researchers develop method for presymptomatic COVID-19 detection

New SARS-CoV-2 variant must be curbed to protect UK health services, warn experts

Probiotics as adjuvant therapy for COVID-19 patients

UC researchers test new combination therapy for head and neck cancer in animal models

SU2C announces $3.25 million in grants to find new treatments for head and neck cancers

New SARS-CoV-2 strain detected in Southern California, USA

How does SARS-CoV-2 infect brain cells?

Patients fend for themselves to access highly touted covid antibody treatments

Gene-cutting system may play second role as a genetic dimmer switch

About 60 percent of SARS-CoV-2 cases in England tied to new variant by the end of December

Essential oils from Greek herbs may protect against COVID-19

SARS-CoV-2 RNA in blood serum could predict COVID-19 mortality

Treating post-infectious smell loss in COVID-19 patients

Surface temperature scanner is an unreliable way to detect fever associated with Covid-19

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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