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Supply chain delays affect planned stockpile of Ebola vaccines

Supply chain delays must be addressed to speed up creation of a stockpile of vaccines against deadly Ebola disease, researchers say.

19 Jan 2021

Novel non-steroid topical cream can safely and effectively treat plaque psoriasis

Psoriasis is a chronic inflammatory skin disease characterized by erythematous (red) patches and plaques.

19 Jan 2021

Early administration of ivermectin could help reduce viral transmission in COVID-19 patients

A small pilot study suggests that early administration of ivermectin can reduce viral loads and symptom duration in patients with mild COVID-19, which in turn could help reduce viral transmission.

19 Jan 2021

New method could provide additional insight into brain tumors

A look at RNA tells us what our genes are telling our cells to do, and scientists say looking directly at the RNA of brain tumor cells appears to provide objective, efficient evidence to better classify a tumor and the most effective treatments.

19 Jan 2021

Prolonged shedding and multiple mutations 154 days after initial SARS-CoV-2 diagnosis reported

An interesting new preprint published on the medRxiv server describes an immunosuppressed patient with coronavirus disease 2019 (COVID-19) who continued to shed the virus for an astounding 154 days. During this period, the virus underwent numerous mutations.

19 Jan 2021

Scientists set research priorities for COVID-19 vaccines

More than 2,800 scientists from 130 countries gathered on Friday (January 15) in a virtual forum hosted by the World Health Organization (WHO) to identify knowledge gaps and set research priorities for vaccines against SARS-CoV-2, the virus that causes COVID-19.

19 Jan 2021

WHO Emergency Committee to review emerging SARS-CoV-2 variants

The COVID-19 pandemic continues to constitute a Public Health Emergency of International Concern (PHEIC), according to the WHO Emergency Committee (EC) on COVID-19.

19 Jan 2021

Understanding the Philippines' relative success with COVID-19

Many high-income countries have reported rising numbers of cases, while a few low-income countries such as the Philippines report a less severe COVID-19 outbreak. To date, the archipelagic country in Southeast Asia has reported 502,000 cases and 9,900 deaths among its population of around 108 million.

18 Jan 2021

Closed SARS-CoV-2 spikes could be a valuable component of future vaccines

Now, researchers at the Medical Research Council Laboratory of Molecular Biology, Cambridge, United Kingdom, reveal that engineered closed S constructs may be valuable immunogens that can induce neutralizing antibodies against a different pattern of epitopes. This allows for the flexibility of vaccines at both the individual and population levels.

18 Jan 2021

Study finds new evidence about the positive role of androgens in breast cancer treatment

Researchers at the University of Adelaide have found new evidence about the positive role of androgens in breast cancer treatment with immediate implications for women with estrogen receptor-driven metastatic disease.

18 Jan 2021

Modified natural killer cells show neutralizing and multivalent potential against SARS-CoV-2 in vitro

A new study suggests that modified natural killer cells, which express a chimeric antigen receptor using S309 antibody, can bind to and inactivate SARS-CoV-2 spike protein in vitro.

18 Jan 2021

Can transgenic mice studies illuminate neurological complications associated with SARS-CoV-2 in humans?

The potentially deadly COVID-19 has not affected animals with corresponding severity. To understand the mechanism of severe disease, animal models have been used. This includes a mouse model that expresses human angiotensin-converting enzyme 2 (hACE2) under the cytokeratin 18 promoter (K18-hACE2). A new study indicates that this may not be a faithful model of human lethal infection with SARS-CoV-2.

18 Jan 2021

What are the key factors and impact of interventions in England’s COVID-19 epidemic?

Researchers from Imperial College London provide a mathematical model to help understand how SARS-CoV-2, the causative pathogen of (COVID-19), spread across England in the first two waves of the epidemic, and the effect of various interventions by the government.

18 Jan 2021

A high-temperature tolerant SARS-CoV-2 derived immunogen as a potential vaccine candidate

There have been significant efforts worldwide to combat COVID-19, the disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). One prominent strategy has been to develop vaccines against the virus. Numerous vaccine candidates are under development, and a handful have now been approved for use by several countries.

17 Jan 2021

Research suggests St. John's Wort and Echinacea could protect against COVID-19

Researchers in Saudi Arabia have conducted a study demonstrating the antiviral effects of two medicinal herbs against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

17 Jan 2021

Analysis supports phase 3 trials of Johnson & Johnson's COVID-19 vaccine

Researchers in the Netherlands, the United States, and Belgium have presented early-stage clinical trial results demonstrating the safety and efficacy of Johnson & Johnson's vaccine candidate for coronavirus disease 2019 (COVID-19).

17 Jan 2021

Study reveals possible SARS-CoV-2 escape mutant that may re-infect immune individuals

A recent study by US researchers shows how the 501Y.V2 variant of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), characterized by several mutations, is able to escape neutralization by present first-wave anti-SARS-CoV-2 antibodies and potentially re-infect COVID-19 convalescent individuals.

17 Jan 2021

Novel biodegradable magnesium-alloy tracheal stents for children with airway obstruction

Pediatric laryngotracheal stenosis (LTS), a narrowing of the airway in children, is a complex medical condition. While it can be something a child is born with or caused by injury, the condition can result in a life-threatening emergency if untreated.

16 Jan 2021

New antiviral repurposing study finds peptides that could prevent SARS-CoV-2-ACE2 binding

A new study reports the antiviral potential of peptides against SARS-CoV-2's spike protein.

15 Jan 2021

Can cloth masks protect healthcare professionals from SARS-CoV-2?

Given the global scarcity of surgical masks, a recent review study examines this issue - dealing with the potential use of cloth masks in healthcare scenarios.

15 Jan 2021

Efficacy News and Research

Supply chain delays affect planned stockpile of Ebola vaccines

Novel non-steroid topical cream can safely and effectively treat plaque psoriasis

Early administration of ivermectin could help reduce viral transmission in COVID-19 patients

New method could provide additional insight into brain tumors

Prolonged shedding and multiple mutations 154 days after initial SARS-CoV-2 diagnosis reported

Scientists set research priorities for COVID-19 vaccines

WHO Emergency Committee to review emerging SARS-CoV-2 variants

Understanding the Philippines' relative success with COVID-19

Closed SARS-CoV-2 spikes could be a valuable component of future vaccines

Study finds new evidence about the positive role of androgens in breast cancer treatment

Modified natural killer cells show neutralizing and multivalent potential against SARS-CoV-2 in vitro

Can transgenic mice studies illuminate neurological complications associated with SARS-CoV-2 in humans?

What are the key factors and impact of interventions in England’s COVID-19 epidemic?

A high-temperature tolerant SARS-CoV-2 derived immunogen as a potential vaccine candidate

Research suggests St. John's Wort and Echinacea could protect against COVID-19

Analysis supports phase 3 trials of Johnson & Johnson's COVID-19 vaccine

Study reveals possible SARS-CoV-2 escape mutant that may re-infect immune individuals

Novel biodegradable magnesium-alloy tracheal stents for children with airway obstruction

New antiviral repurposing study finds peptides that could prevent SARS-CoV-2-ACE2 binding

Can cloth masks protect healthcare professionals from SARS-CoV-2?

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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