Nephrology News and Research

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Nephrology is a branch of internal medicine and pediatrics dealing with the study of the function and diseases of the kidney.

High-risk surgery patients have shorter hospital stays when their care was co-managed by hospitalists

A Loyola University Health System study has found that high-risk surgery patients experienced significantly shorter hospital stays when they were seen by general internists trained in managing medical complications in surgical patients.

3 Oct 2009

Research study suggests possibility of safely expanding donor kidney pool by 10 to 15 percent

Kidneys recovered from deceased donors with acute renal failure (ARF) - once deemed unusable for transplant - appear to work just as well as kidneys transplanted from deceased donors who do not develop kidney problems prior to organ donation, according to a new study by researchers at Wake Forest University Baptist Medical Center.

3 Oct 2009

Study finds link between allergic inflammation and nephropathy in men with type 2 diabetes

For men with type 2 diabetes, a cell type linked to allergic inflammation is closely linked to a key indicator of diabetic kidney disease (nephropathy), suggests a study in the November Clinical Journal of the American Society of Nephrology (CJASN). "Allergy is a common disease that is increasing worldwide, so our findings may have important implications for diabetic nephropathy," comments Michiaki Fukui, MD (Kyoto Prefectural University of Medicine, Japan).

3 Oct 2009

American Kidney Fund to host national gala to support kidney care community

In celebration of people who are living with kidney disease, as well as the individuals and corporations who are working to improve the lives of kidney patients, the American Kidney Fund will host its first national gala, The Hope Affair, at the Newseum on October 6.

3 Oct 2009

Dapagliflozin with metformin reduces glycosylated hemoglobin level and body weight

Results from a 24-week phase 3 clinical study demonstrated that the investigational drug dapagliflozin, added to metformin, demonstrated significant mean reductions in the primary endpoint, glycosylated hemoglobin level (HbA1c) and in the secondary endpoint, fasting plasma glucose (FPG) in patients with type 2 diabetes inadequately controlled with metformin alone, as compared to placebo plus metformin.

3 Oct 2009

Study sheds light on why some hospitals have lower mortality than others

A compelling University of Michigan Health System study debunks assumptions about the role of complications in distinguishing good and bad hospitals.

1 Oct 2009

Altered state physiology drug development platform to treat an array of human conditions

David H. Fater, CEO of Vicor Technologies, Inc., today announced that on July 23, 2009, the Australian Patent Office issued it a Deed of Letters Patent for its altered state physiology drug development platform. Vicor Technologies is a biotechnology company focused on the commercialization of innovative, non-invasive medical devices and diagnostics using its patented, proprietary PD2i® nonlinear algorithm and software to stratify patients at risk of sudden cardiac death and trauma victims in need of lifesaving intervention.

1 Oct 2009

Study reveals how kidney repair processes are controlled

A study by Monash University researchers has shed new light on the microscopic antennas in the kidney that are involved in the organ's repair process.

1 Oct 2009

Medgenics announces unaudited half-yearly results for the six months ended 30 June 2009

Medgenics (AIM:MEDG) (AIM:MEDU) is pleased to announce its unaudited half-yearly results for the six months ended 30 June 2009.

30 Sep 2009

Dynavax commences Phase 3 trial for HEPLISAV hepatitis B vaccine

Dynavax Technologies Corporation (Nasdaq:DVAX) today announced the initiation of a Phase 3 registration trial for HEPLISAVTM hepatitis B vaccine in individuals with chronic kidney disease. A second registration trial, a Phase 3 lot-to-lot consistency trial, is expected to begin in early 2010. HEPLISAV is an investigational adult hepatitis B vaccine designed to provide increased, rapid protection with fewer doses than current licensed vaccines.

29 Sep 2009

Minimally invasive mitral valve surgery is safe and effective

Surgical treatment for mitral valve disease includes either repairing the patient's diseased valve or replacing it with a metal, mechanical valve or an animal tissue valve. The majority of those procedures are open-heart operations that require a major incision in the chest. Now, after a six-year study, surgeons at the University of Maryland Medical Center in Baltimore conclude that minimally invasive mitral valve repair techniques, through only a two-inch incision in the right side of the chest, are safe, durable and effective. The results are published in the September 2009 Annals of Surgery.

29 Sep 2009

Poor kidney function can affect brain activities

A new study published in the medical journal Neurology suggests that impaired kidney function is a risk factor for cognitive decline in old age.

29 Sep 2009

Dialysis patients often not told about transplant options, Newspaper finds

"Thousands of kidney patients in the United States start dialysis without first being told of kidney transplants that would be cheaper and lead to longer lives, according to a four-month newspaper investigation published Sunday," The Associated Press reports.

28 Sep 2009

NIH awards DiscoveryBioMed a Phase 2 SBIR grant for research on hypertension and cystic fibrosis

DiscoveryBioMed, Inc. (DBM) today announced that it has been awarded a $750,000 Small Business Innovations Research (SBIR) Phase 2 grant by the National Institutes of Health (NIH) to continue the research into the discovery and development of small molecules to alleviate multiple chronic human diseases including cystic fibrosis (CF), hypertension and chronic kidney diseases with hypertension.

28 Sep 2009

Child health experts to gather in Italy for Excellence in Paediatrics conference

Obesity, the flu pandemic and diabetes are just three of the hot topics that will be explored when top child health experts gather in Italy for Excellence in Paediatrics from 3 to 6 December 2009.

28 Sep 2009

Phase 2 clinical trial results of IMO-2055 announced

Idera Pharmaceuticals, Inc., today announced the presentation of final data from a clinical trial evaluating IMO-2055, an agonist of Toll-like Receptor (TLR) 9, as monotherapy in patients with Renal Cell Carcinoma (RCC). The data are being presented during the Eighth International Kidney Cancer Symposium being held in Chicago, September 25-26, 2009.

28 Sep 2009

EMS provides free resources for protection against swine flu

Emergency Management & Safety Solutions (EMS), the crisis planner for many Fortune 100 companies, international government agencies and large non-profit organizations, is providing free resources to help people prepare for, prevent transmission of and take care of the ill to survive this wave of this year’s H1N1 flu pandemic. Today, over 180 countries have experienced the H1N1 virus outbreak and at least 3,486 people have died – including 1,000 Americans.

26 Sep 2009

Research to improve the targeting of chemotherapeutic drugs to specific cells

Kenneth Longmuir, associate professor of physiology & biophysics, and Richard Robertson, professor of anatomy & neurobiology, used liposomes, small spheres (less-than 100 nanometer in diameter) of naturally-occurring lipid molecules, as "packages" for the cancer chemotherapeutic agent doxorubicin, and a small peptide molecule to "address" the package to the targeted tissue.

25 Sep 2009

iCo Therapeutics, CPDD sign collaboration development agreement

iCo Therapeutics Inc. (TSX-V: ICO) is pleased to announce that the company has signed a collaboration development agreement with The Consortium for Parasitic Drug Development (CPDD) for the research and development of iCo's oral drug delivery technology for the treatment of neglected diseases such as leishmaniasis and trypanosomiasis. Initial funding of USD $182,930 will be provided for formulation optimization for tropical conditions.

25 Sep 2009

Study reveals that kidney transplants do not affect pregnancy

Women who have had a kidney transplant and have good kidney function can get pregnant and give birth without jeopardizing their health or the health of their transplant. Having children does not affect patients' kidney function or their life-span compared with transplanted women who do not have children, according to a matching cohort study appearing in an upcoming issue of the Journal of the American Society Nephrology (JASN).

25 Sep 2009

Nephrology News and Research

Further Reading

High-risk surgery patients have shorter hospital stays when their care was co-managed by hospitalists

Research study suggests possibility of safely expanding donor kidney pool by 10 to 15 percent

Study finds link between allergic inflammation and nephropathy in men with type 2 diabetes

American Kidney Fund to host national gala to support kidney care community

Dapagliflozin with metformin reduces glycosylated hemoglobin level and body weight

Study sheds light on why some hospitals have lower mortality than others

Altered state physiology drug development platform to treat an array of human conditions

Study reveals how kidney repair processes are controlled

Medgenics announces unaudited half-yearly results for the six months ended 30 June 2009

Dynavax commences Phase 3 trial for HEPLISAV hepatitis B vaccine

Minimally invasive mitral valve surgery is safe and effective

Poor kidney function can affect brain activities

Dialysis patients often not told about transplant options, Newspaper finds

NIH awards DiscoveryBioMed a Phase 2 SBIR grant for research on hypertension and cystic fibrosis

Child health experts to gather in Italy for Excellence in Paediatrics conference

Phase 2 clinical trial results of IMO-2055 announced

EMS provides free resources for protection against swine flu

Research to improve the targeting of chemotherapeutic drugs to specific cells

iCo Therapeutics, CPDD sign collaboration development agreement

Study reveals that kidney transplants do not affect pregnancy

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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