Immune System News and Research

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Study sheds light on how ‘junk DNA’ affects inherited cancer risk

A person’s risk of developing cancer is affected by genetic variations in regions of DNA that don’t code for proteins, previously dismissed as ‘junk DNA’, according to new research published in the British Journal of Cancer today (Friday).

6 Dec 2019

Cancer in the eye does not always develop into central nervous system lymphoma

Researchers at Okayama University report in the Journal of clinical and experimental hematopathology that primary intraocular lymphoma, a cancer in the eye, does not always develop into central nervous system lymphoma.

6 Dec 2019

Researchers confirm two new prognostic markers for triple negative breast cancer

Physicians who treat patients with triple negative breast cancer have two new ways to predict which patients may benefit most from the well-established post-surgery treatment known as AC chemotherapy, short for adjuvant doxorubicin and cyclophosphamide.

5 Dec 2019

Perinatal maternal antibiotic exposure may impair lung development in premature infants

New research in mice suggests that exposure to antibiotics before birth may impair lung development in premature infants. The study, the first to explore the gut-lung axis in prematurity, is published ahead of print in the American Journal of Physiology—Lung Cellular and Molecular Physiology and was chosen as an APSselect article for December.

5 Dec 2019

No differences found in survival, acute rejection in patients receiving lungs from increased-risk donors

Cleveland Clinic researchers have found that using lungs from donors who are considered high risk for certain infectious diseases compared to standard risk donors results in similar one-year survival for recipients. In addition, researchers saw no difference in rejection or graft (donor lung) survival after one year in patients receiving lungs from increased-risk donors.

5 Dec 2019

Early diagnosis and treatment of chronic inflammation may reduce illness, save lives

Scientists from 22 institutions, including UCLA, are recommending early diagnosis, prevention and treatment of severe chronic inflammation to reduce the risk of chronic disease and death worldwide.

5 Dec 2019

Using drug-eluting medical devices to fight bacterial infections

Medical practitioners routinely outfit patients with devices ranging from cardiovascular stents, pacemakers, catheters, and therapeutic lenses to orthopedic, breast, dental, and cochlear implants and prostheses.

5 Dec 2019

FDA-approved drug repairs gut leakiness associated with ulcerative colitis

A research team led by biomedical scientists at the University of California, Riverside, has found that a drug approved by the FDA to treat rheumatoid arthritis and ulcerative colitis can repair permeability defects in the gut's epithelium.

4 Dec 2019

Ground breaking discovery could lead to new anti TB drugs

New drugs to treat strains of TB which have become resistant to treatment are now a possibility following a ground breaking discovery from the University of Surrey.

4 Dec 2019

Study shows intestinal involvement in the development and progression of MS

It is incompletely understood which factors in patients with multiple sclerosis (MS) act as a trigger for the immune system to attack the brain and spinal cord.

4 Dec 2019

Study reveals role of corpora amylacea in expelling brain waste substances

An article published in Proceedings of the National Academy of Sciences describes a new pathway in the central nervous system to expel waste substances from the brain through the creation of corpora amylacea, aggregates formed by glucose polymers amassing waste products.

4 Dec 2019

New study could help prevent fatal infections in babies

Premature infants born before 28-30 weeks of life are at high risk for many complications, among which the chances of dying from an infection starting in the intestine are very great. A new study published in the journal Nature Medicine reports that such infections are very much more likely if something interferes with the normal microbial accumulation in the gut. Adding certain bacterial strains protects against such infections, on the other hand.

3 Dec 2019

New screening method can rapidly discover potential cancer-treating compounds

Scientists at Scripps Research have developed a method for rapidly discovering potential cancer-treating compounds that work by resurrecting anti-tumor activity in immune cells called T cells.

3 Dec 2019

Dynamics of crucial immune system proteins revealed

Of the many marvels of the human immune system, the processing of antigens by the class I proteins of the major histocompatability complex (MHC-I) is among the most mind-boggling. Exactly how these proteins carry out their crucial functions has not been well understood.

3 Dec 2019

Transplant patients diagnosed with prostate cancer may not need to delay transplantation

Immunosuppressive medications – drugs given to organ transplant recipients so their bodies won't reject the donor organ - could weaken the immune system's ability to find and destroy cancer or fight infections that contribute to cancer.

3 Dec 2019

Streamlining Immuno-Oncological Therapeutic Antibody Discovery

The growing trend of implementing immunotherapy into oncology has resulted in various new therapeutic cancer treatments utilizing antibodies.

From Sartorius 3 Dec 2019

Study: TBK1 protein promotes cancer development, suppresses immune response to the disease

Researchers at The University of Texas MD Anderson Cancer Center have found that a protein involved in immune response to microbes also can fuel cancer development and suppress immune response to the disease.

3 Dec 2019

Key component of immune response is activated by short RNAs, shows study

Ludwig-Maximilians-Universitaet (LMU) in Munich researchers report that a central component of the innate immune response is activated by two short RNAs which are produced by site-specific cleavage of a precursor RNA molecule - and both derivatives are generated by the same enzyme.

3 Dec 2019

Unexpected versatility of an ancient DNA repair factor revealed

If a bone breaks or a tendon snaps, you know to seek treatment immediately. But your most fragile and precious cellular commodity, chromosomal DNA, breaks with astounding frequency- some estimate as many as 10,000 times a day per cell- usually without consequence.

2 Dec 2019

Virome analysis reveals clues for increased risk of type 1 diabetes in children

New results from The Environmental Determinants of Diabetes in the Young study show an association between prolonged enterovirus infection and the development of autoimmunity to the insulin-producing pancreatic beta-cells that precedes type 1 diabetes.

2 Dec 2019