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Researchers use layered double hydroxide to increase neuronal growth in mice with spinal cord injuries

Researchers from the Department of Orthopedics of Tongji Hospital at Tongji University in Shanghai have successfully used a nanobiomaterial called layered double hydroxide (LDH) to inhibit the inflammatory environment surrounding spinal cord injuries in mice, accelerating regeneration of neurons and reconstruction of the neural circuit in the spine.

23 Mar 2021

YAP inhibitors could facilitate targeted treatment of basal-like breast cancer

Targeted treatment of basal-like breast cancer could be facilitated by YAP inhibitors in the future. As reported by an MDC team headed by Walter Birchmeier in the scientific journal Cancer Research, this type of cancer requires the support of the YAP protein to stimulate the growth of cancer stem cells.

22 Mar 2021

SARS-CoV-2 variants develop resistance against type I interferons

A study conducted at the University of Colorado and National Institutes of Health, USA, has revealed that the resistance developed by newly emerging variants of SARS-CoV-2 against host interferon responses could serve as a potential driving force for viral evolution.

22 Mar 2021

Chaotic genetic changes drive the growth of melanomas

Melbourne researchers have revealed how melanoma cells are flooded with DNA changes as this skin cancer progresses from early, treatable stages through to fatal end-stage disease.

22 Mar 2021

Male fertility and androgen production may be impacted by COVID-19

An interesting new study has appeared online in the journal Hormones that discusses the effects of COVID-19 on the male and female gonads.

22 Mar 2021

Novel technology may reveal the brain's mysteries

A team of scientists, led by researchers at Northwestern University, Shirley Ryan AbilityLab and the University of Illinois at Chicago (UIC), has developed novel technology promising to increase understanding of how brains develop, and offer answers on repairing brains in the wake of neurotrauma and neurodegenerative diseases.

22 Mar 2021

Ubiquitous microplastics can become 'hubs' for antibiotic-resistant bacteria

It's estimated that an average-sized wastewater treatment plant serving roughly 400,000 residents will discharge up to 2,000,000 microplastic particles into the environment each day.

22 Mar 2021

First model of early human embryo generated from skin cells

In a discovery that will revolutionise research into the causes of early miscarriage, infertility and the study of early human development - an international team of scientists led by Monash University in Melbourne, Australia has generated a model of a human embryo from skin cells.

22 Mar 2021

Genetic engineering strategy dramatically reduces tau levels in Alzheimer's animal model

Researchers have used a genetic engineering strategy to dramatically reduce levels of tau--a key protein that accumulates and becomes tangled in the brain during the development of Alzheimer's disease--in an animal model of the condition.

21 Mar 2021

Acute exposure of lung tissue to vape aerosol has lesser impact on gene expression than cigarette smoke

A new peer-reviewed study published in the journal Toxicological Research & Application shows acute exposure of a 3D human bronchial tissue model to e-cigarette aerosol has minimal impact on gene expression compared to smoke from combustible cigarettes.

21 Mar 2021

Hidden genetic defects can lead to all kinds of serious illnesses

For the first time researchers from Hebrew University of Jerusalem, Radboudumc, Maastricht UMC+ and international colleagues have gained insight into the "hidden genetic defects" of the general European population.

19 Mar 2021

SARS-CoV-2 spike stimulates hyperinflammation via Toll-like receptor 2

A new study, released on the bioRxiv* preprint server, describes the mechanism of inflammation in severe COVID-19, besides revealing a potential new therapeutic target to modulate the severity of COVID-19.

19 Mar 2021

Researchers characterize regions of DNA that impact MECP2 expression

Researchers at Baylor College of Medicine and the Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital (NRI) have identified and characterized two regions of DNA required for the proper expression of Mecp2/MECP2 in mice and humans.

19 Mar 2021

New proteomics method helps confirm COVID-19 transmission from mother to fetus

Researchers from Skoltech were part of a research consortium studying a case of vertical COVID-19 transmission from mother to her unborn child that resulted in major complications in the pregnancy, premature birth and death of the child.

19 Mar 2021

Study reveals how SARS-CoV-2 spread in Wuhan before the lockdown

Using molecular dating tools and epidemiological simulations, researchers at University of California San Diego School of Medicine, with colleagues at the University of Arizona and Illumina, Inc., estimate that the SARS-CoV-2 virus was likely circulating undetected for at most two months before the first human cases of COVID-19 were described in Wuhan, China in late-December 2019.

19 Mar 2021

Weight loss induced by diet and bariatric surgery has different impact on mitochondria in fat tissue

Dieting impairs the energy-producing machinery of fat tissue, potentially resulting in weight regain. In contrast, as indicated by a recently completed European study coordinated by the University of Helsinki, weight loss surgery gives a boost to mitochondria, improving the gene expression of these cellular engines.

18 Mar 2021

Study investigates how genetic variants contribute to increased risk of lung cancer

Lung cancer is the leading cause of cancer death in the U.S. for both men and women. While risk for this disease can be influenced by environmental and lifestyle factors like smoking, studies estimate that 18% of lung cancer cases are due to inherited genetic variants.

18 Mar 2021

Anti-inflammatory therapies may help prevent heart disease in people with age-related blood condition

Therapies that soothe inflammation could be an effective way to prevent heart disease in people with a common age-related blood condition, according to a new study from researchers at Columbia University Vagelos College of Physicians and Surgeons.

18 Mar 2021

Researchers identify inflammatory mechanism related to bone damage in rheumatoid arthritis

In a study aimed at investigating the mechanism responsible for exacerbating rheumatoid arthritis in smokers, researchers at the Center for Research on Inflammatory Diseases, linked to the University of São Paulo in Brazil, discovered a novel path in the inflammatory process associated with the bone damage caused by rheumatoid arthritis.

18 Mar 2021

Study confirms that higher level of maternal folate increases the child’s birthweight

Imagine that you are going to conduct research on how different factors affect a child in the womb. Bad habits such as smoking, drinking alcohol or poor eating habits are factors that may affect the child.

18 Mar 2021

Genes News and Research

Researchers use layered double hydroxide to increase neuronal growth in mice with spinal cord injuries

YAP inhibitors could facilitate targeted treatment of basal-like breast cancer

SARS-CoV-2 variants develop resistance against type I interferons

Chaotic genetic changes drive the growth of melanomas

Male fertility and androgen production may be impacted by COVID-19

Novel technology may reveal the brain's mysteries

Ubiquitous microplastics can become 'hubs' for antibiotic-resistant bacteria

First model of early human embryo generated from skin cells

Genetic engineering strategy dramatically reduces tau levels in Alzheimer's animal model

Acute exposure of lung tissue to vape aerosol has lesser impact on gene expression than cigarette smoke

Hidden genetic defects can lead to all kinds of serious illnesses

SARS-CoV-2 spike stimulates hyperinflammation via Toll-like receptor 2

Researchers characterize regions of DNA that impact MECP2 expression

New proteomics method helps confirm COVID-19 transmission from mother to fetus

Study reveals how SARS-CoV-2 spread in Wuhan before the lockdown

Weight loss induced by diet and bariatric surgery has different impact on mitochondria in fat tissue

Study investigates how genetic variants contribute to increased risk of lung cancer

Anti-inflammatory therapies may help prevent heart disease in people with age-related blood condition

Researchers identify inflammatory mechanism related to bone damage in rheumatoid arthritis

Study confirms that higher level of maternal folate increases the child’s birthweight

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