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Cumulative cardiovascular health from early adulthood predicts lower disease risk

The American Heart Association's Life's Essential 8 (LE8) score is a health tool, ranging from 0 to 100, that quantifies cardiovascular health (CVH) using information from eight lifestyle and risk factors, (body mass index, cholesterol, blood pressure, blood glucose, physical activity, diet, smoking, and sleep.

28 Apr 2026

Study suggests a U-shaped link between cholesterol levels and mortality among Chinese adults

A new commentary published in Engineering highlights key findings from a large multinational cohort study that re-evaluates cholesterol management for cardiovascular and chronic disease prevention, suggesting a U-shaped association between cholesterol levels and mortality among Chinese adults that challenges the conventional "lower is better" approach.

28 Apr 2026

TikTok chatter could help predict where the opioid crisis is heading next

A large-scale analysis of 569,581 TikTok comments found that opioid-related discussions may help track and forecast synthetic opioid overdose mortality in the US. Recovery, harm reduction, drug use, drug sourcing, and loss-related conversations provided near-real-time signals that improved 6-month forecasting accuracy.

28 Apr 2026

UBC researchers develop new way to target previously undruggable proteins

Researchers at the University of British Columbia and BC Cancer have developed a new way to target proteins long considered "undruggable," opening the door to new treatments for prostate cancer and other serious diseases.

28 Apr 2026

New scientific statement defines brain health across life

Brain health isn't determined only by genetics or what happens later in life. A growing body of research shows that a range of factors-from mental health and sleep to environment, lifestyle and social conditions-play a powerful role in shaping how the brain functions and ages.

28 Apr 2026

The simple link between core strength and brain health

The brain is more mechanically connected to the body than previously appreciated, scientists reported today (April 27) in Nature Neuroscience. Through a study using mice and simulations, the team found a potential biological mechanism underlying why exercise is thought to benefit brain health: abdominal contractions compress blood vessels connected to the spinal cord and the brain, enabling the organ to gently move within the skull.

28 Apr 2026

A new biological switch to slow atherosclerosis progression

A study by researchers at Baylor College of Medicine and collaborating institutions reveals a previously unrecognized way blood vessels can protect themselves from damage and slow the development of atherosclerosis. The findings, published in the Proceedings of the National Academy of Sciences, have implications for both vascular precision medicine and the safety of certain emerging cancer treatments.

28 Apr 2026

Lipid pathways driving diabetes and heart disease risk in South Asians

Identifying lipid-linked genetic pathways in Asian Indians offers insights into diabetes and heart disease, crucial for developing ancestry-specific therapies.

28 Apr 2026

Noninvasive brain monitoring reveals hidden oxygen deprivation in ICU patients

In neurological intensive care, it is quickly learned that the brain cannot wait. As the most sensitive organ in the human body, it can sustain irreversible damage after just a few minutes of severe hypoxia.

27 Apr 2026

Ablation can lead to better outcomes for patients with advanced atrial fibrillation

A minimally invasive heart procedure may be a better first-line treatment than medication for people living with advanced forms of atrial fibrillation, according to a major international clinical trial led by researchers at the University of British Columbia.

27 Apr 2026

Delayed adrenaline use linked to fatal childhood food anaphylaxis

Fatal delays in administering life-saving adrenaline autoinjector (EpiPen) for food anaphylaxis, a severe and rapid allergic reaction, is highlighted in research being presented at the Royal College of Emergency Medicine Conference today [28 April].

27 Apr 2026

Single protein shapes both brain connectivity and vascular stability

The communication network in the developing brain builds when neurons partner up to form contact points called synapses, allowing signals to pass form one cell to another.

27 Apr 2026

Three cognitive trajectories identified in preclinical Alzheimer’s disease

Cognitive decline in Alzheimer's disease differs substantially from one person to the next and is not well predicted by existing medical tests.

27 Apr 2026

Twice-yearly blood pressure treatment could reshape hypertension care, but doctors warn against a “fire-and-forget” approach

Long-acting RNA interference therapy for hypertension could shift blood pressure control from daily pill-taking to scheduled, system-led protection. But the authors warn that this “vaccine-like” model must preserve lifestyle support, monitoring, and follow-up to avoid clinical disengagement.

27 Apr 2026

NIH awards five year grant for cardiovascular epidemiology training

Boston University Chobanian & Avedisian School of Medicine researchers Vanessa Xanthakis, PhD, FAHA, associate professor of medicine and director of research training, and Mathew Nayor, MD, MPH, associate professor of medicine, have been awarded a five-year, T32 grant from the National Institutes of Health's National Heart, Lung and Blood Institute

27 Apr 2026

Advanced heart, kidney and metabolic disease linked to higher cancer risk

People with advanced heart, kidney and metabolic disease may face a higher risk of developing cancer, according to new research published today in the American Heart Association's peer-reviewed scientific journal Circulation: Population Health and Outcomes.

27 Apr 2026

Estrogen loss after menopause impacts heart health through gene regulation

Virginia Tech scientists at the Fralin Biomedical Research Institute say the increased risk of cardiovascular disease after menopause may stem not only from declining hormone levels, but also from how those changes influence gene activity.

27 Apr 2026

Yoga to help manage obesity-related heart and metabolic risks

The impact of yoga on heart health in obesity is modest, suggesting it as a complementary approach for improving metabolic outcomes in high BMI populations.

27 Apr 2026

Blue Zones longevity claims may rest on flawed records, essay argues

Essay challenges the scientific validity of the Blue Zones concept and Ancel Keys’ Lipid Hypothesis, arguing that both rest on biased data, weak records, and methodological flaws. The authors say some longevity claims may reflect clerical errors, poverty, and unreliable vital records rather than uniquely healthy lifestyles.

26 Apr 2026

Experts debate benefits and costs of robotic lung transplantation

The expanding use of robotic technology in lung transplantation came under scrutiny at today's 46th Annual Meeting and Scientific Sessions of the International Society for Heart and Lung Transplantation (ISHLT), where experts debated whether its clinical benefits justify the cost and complexity.

25 Apr 2026