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Study unveils role of TLE6 in male sperm development

Infertility is a major global challenge associated with physiological and psychological impact. Genetic mutations that affect early embryonic development, oocyte (egg cell) maturation, and fertilization have recently been studied as causes of infertility.

16 Jan 2025

Spear Bio secures FDA breakthrough device designation for its novel pTau 217 blood test, advancing scalable solutions for early Alzheimer's disease diagnosis

Spear Bio Inc., a biotechnology company pioneering next-generation ultra-sensitive immunoassays, today announced that its pTau 217 blood test has been granted Breakthrough Device Designation by the U.S. Food and Drug Administration (FDA).

From Spear Bio 15 Jan 2025

UQ and Vaxxas win global prize to accelerate patch-based mRNA vaccine for COVID-19

The University of Queensland's BASE facility – within the Australian Institute for Bioengineering and Nanotechnology (AIBN) – and Brisbane-based biotechnology company Vaxxas have been announced as stage winners of a prestigious global prize to accelerate a patch-based mRNA vaccine for COVID-19.

13 Jan 2025

Experimental blood test for pancreatic cancer moves closer to real-world use

An experimental blood test for pancreatic cancer that was developed by Van Andel Institute and University of Pittsburgh scientists is being evaluated by a commercial laboratory, an important milestone toward making the test available for patients.

13 Jan 2025

COVID-19 vaccine developed by Brazilian researchers shows promise in mice

Studies conducted in mice have shown that the COVID-19 vaccine being developed by researchers at the University of São Paulo's Medical School (FM-USP) in Brazil is safe and efficacious.

13 Jan 2025

Genetic discoveries drive new approaches to treating cerebral vascular malformations

Cerebral vascular malformations (CVMs), including cerebral arteriovenous malformations (AVMs) and cavernous malformations (CCMs), have long posed challenges due to their complex origins and severe clinical implications.

13 Jan 2025

Boston Scientific announces agreement to acquire Bolt Medical, Inc.

Boston Scientific Corporation today announced it has entered into a definitive agreement to acquire Bolt Medical, Inc., the developer of an intravascular lithotripsy (IVL) advanced laser-based platform for the treatment of coronary and peripheral artery disease.

From Boston Scientific 13 Jan 2025

NIH grant supports study of copper's role in killing harmful bacteria

A researcher at the University of Arizona College of Medicine – Tucson received a $1.9 million grant from the National Institutes of Health to continue his research into uncovering the mysteries of copper – specifically, how it can be harnessed to kill harmful bacteria and other microorganisms.

10 Jan 2025

RNAConnect Debuts The New UltraMarathonRT® RT-qPCR Kit to Improve Reliability Of Gene Expression Analysis

UltraMarathonRT® RT-qPCR Kit offers unmatched data reliability and sensitivity for gene expression studies, streamlining workflows and preserving RNA integrity.

From RNAConnect 10 Jan 2025

Breakthrough in chemical synthesis expands possibilities for ketones and esters

Scientists have long considered ketones (a fundamental chemical class) and esters (molecules formed when an acid reacts with an alcohol) to be locked treasure chests of possibilities.

10 Jan 2025

Groundbreaking research uncovers how neurons organize natural behaviors

Eight years of work. A collaboration between the Laboratory of Neuroethology of Non-Human Primates of the Department of Medicine and Surgery of the University of Parma, led by Luca Bonini, and a team from the Biorobotics Institute of the Sant'Anna School of Pisa, coordinated by Alberto Mazzoni, principal investigator at the Computational Neuroengineering Lab, with the contribution of Silvestro Micera, professor in Bioingeneering.

10 Jan 2025

AI-enhanced algorithm improves diagnosis of REM sleep behavior disorder

A Mount Sinai-led team of researchers has enhanced an artificial intelligence (AI)-powered algorithm to analyze video recordings of clinical sleep tests, ultimately improving accurate diagnosis of a common sleep disorder affecting more than 80 million people worldwide.

9 Jan 2025

Geneoscopy closes $105 M in Series C funding round to power next-generation of gastrointestinal diagnostic tests

Geneoscopy, Inc., a life sciences company focused on developing diagnostic tests for the advancement of gastrointestinal health, today announced the closing of a Series C funding round raising $105 million.

9 Jan 2025

Monoamine neurotransmitters emerge as architects of brain physiology

A collaborative effort between Mount Sinai and Memorial Sloan Kettering Cancer Center has shed valuable light on how monoamine neurotransmitters such as serotonin, dopamine, and now histamine help regulate brain physiology and behavior through chemical bonding of these monoamines to histone proteins, the core DNA-packaging proteins of our cells.

9 Jan 2025

Childhood stress impacts epigenetic profile of sperm and brain development

Childhood stress can impact the epigenetic profile of sperm. These results may also have practical implications for future generations through epigenetic inheritance, as many of the observed epigenetic associations are related to brain development.

8 Jan 2025

Researchers enhance longevity of neural implants with protective coating

Neural implants contain integrated circuits (ICs) — commonly called chips — built on silicon. These implants need to be small and flexible to mimic circumstances inside the human body.

7 Jan 2025

Innovative biocontrol technique targets female insects to control mosquito-borne diseases

A genetic biocontrol method which reduces the lifespan of female insects could work as fast as pesticides to reduce populations of disease-spreading mosquitoes and destructive crop pests, according to researchers.

7 Jan 2025

POCUS reduces emergency visits and improves pregnancy care

Published in Annals of Family Medicine, a University of Minnesota Medical School research team found that implementing point-of-care ultrasounds (POCUS) to assess the viability and gestational age of pregnancies in the first trimester enhanced care for pregnant patients and cut emergency visits by 81% for non-miscarrying patients.

6 Jan 2025

Early results of doxy PEP rollout show mixed impact on STIs

As health care services begin offering doxycycline to prevent bacterial sexually transmitted infections (STIs), real-world evidence demonstrates that the postexposure strategy, called doxy PEP, is reducing the rate of syphilis and chlamydia, but has had little to no effect on gonorrhea and needs close monitoring for signals of antibiotic resistance.

6 Jan 2025

Inogen receives FDA 510(k) clearance for SIMEOX 200 airway clearance device

Inogen, Inc., a medical technology company offering innovative respiratory products for use in the homecare setting, today announced that it has received U.S. Food and Drug Administration (FDA) 510(k) clearance for the SIMEOX 200 Airway Clearance Device, expanding the company’s ability to market and meet the various needs of patients with chronic respiratory diseases in the U.S.

6 Jan 2025