Clinical Trial News and Research

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Cascade of costs could push new gene therapy above $1 million per patient

Outrage over the high cost of cancer care has focused on skyrocketing drug prices, including the $475,000 price tag for the country's first gene therapy, Novartis' Kymriah, a leukemia treatment approved in August.

17 Oct 2017

Dietary combination transforms lethal breast cancers into highly treatable form

Researchers at the University of Alabama at Birmingham have found a dietary combination that transforms the most lethal of all breast cancers into a highly treatable breast cancer.

17 Oct 2017

Portable scanner can measure limb disfigurement easily in patients with elephantiasis

An estimated 120 million people worldwide are infected with lymphatic filariasis, a parasitic, mosquito-borne disease that can cause major swelling and deformity of the legs, a condition known as elephantiasis.

16 Oct 2017

Investigating new cancer therapy candidates with live-cell imaging

There are two main things that we've worked on in the lab as regards to drug studies. One is identifying new combinations of drugs, and working on why a combination of drugs should work better than each alone.

From Sartorius 16 Oct 2017

TGen awarded $2.5 million SU2C grant to test new method of treating pancreatic cancer

Stand Up To Cancer has awarded a $2.5 million SU2C CatalystR grant to the Translational Genomics Research Institute to investigate a revolutionary new method of treating pancreatic cancer, one of the most aggressive of all cancers.

13 Oct 2017

New study describes unique role of androgens in kidney cancer

A new study is believed to be the first to describe the unique role of androgens in kidney cancer, and it suggests that a new approach to treatment, targeting the androgen receptor (AR), is worth further investigation.

13 Oct 2017

Researchers develop new ‘visual biofeedback’ system for speech therapy

A team of researchers in the GIPSA-Lab and at INRIA Grenoble Rhône-Alpes has developed a system that can display the movements of our own tongues in real time.

13 Oct 2017

Phase 3 clinical trial for compound that shows promise in treatment of Rett syndrome

Rettsyndrome.org is pleased to share that Neuren Pharmaceuticals, today, after meeting with the FDA, will conduct a Phase 3 clinical trial for trofinetide, a compound that shows great promise in the treatment of Rett syndrome, in children and adults.

13 Oct 2017

Higher level of tumor-infiltrating lymphocytes linked to better survival for ovarian cancer patients

A group of international cancer researchers led by investigators from Mayo Clinic and University of New South Wales Sydney has found that the level of a type of white blood cell, called tumor-infiltrating lymphocytes, present in the tumors of patients with high-grade ovarian cancer may predict a patient's survival.

12 Oct 2017

Salk scientists receive $2.5 million funding to conduct pancreatic cancer clinical study

Salk Professor and HHMI Investigator Ronald Evans has been awarded $2.5 million by Stand Up 2 Cancer (SU2C) as part of a multi-institution team to conduct clinical studies to open up a new avenue for immunotherapy in the treatment of pancreatic cancer.

12 Oct 2017

Study provides detailed characterization of neurotoxicity arising from CD19 CAR T-cell therapy

New potential biomarkers and a novel algorithm could help identify patients at increased risk of suffering from severe neurotoxicity after receiving CD19 CAR T-cell therapy. The study extensively characterized common and occasionally fatal side effects of this immunotherapy.

12 Oct 2017

Existing drugs could help patients with rare form of bone cancer

Patients with a rare bone cancer of the skull and spine - chordoma - could be helped by existing drugs, suggest scientists from the Wellcome Trust Sanger Institute, University College London Cancer Institute and the Royal National Orthopaedic Hospital NHS Trust.

12 Oct 2017

New project to seek answers for effects of alcohol on the nervous system

When a drink at the local watering hole turns into five or six, what are the effects on our brains and hearts? How does too much to drink affect how we sleep? How does binge drinking affect blood pressure for people who drink socially but not usually to excess? Do women's bodies process alcohol differently depending on stages of their menstrual cycles?

11 Oct 2017

Clinical trial tests frankincense as potential breast, colon cancer treatment

Cancer surgeon and researcher Nancy DeMore is leading a clinical trial using frankincense to try to treat breast and colon cancer at the Medical University of South Carolina. The study was inspired by a research specialist in DeMore's lab.

11 Oct 2017

Allergy medication restores nervous system function in patients with chronic MS

In a remarkably rapid translation of laboratory research findings into a treatment with the potential to benefit patients, UC San Francisco scientists have successfully completed a Phase II clinical trial showing that an FDA-approved antihistamine restores nervous system function in patients with chronic multiple sclerosis (MS).

11 Oct 2017

New smell test could help improve early diagnosis of Alzheimer's, Parkinson's diseases

Nisha Pradhan was seven when she began to suspect she was missing out on something. Her sister seemed to have an uncanny knack for predicting what their mother was making for dinner. Pradhan, meanwhile, never had a clue.

11 Oct 2017

Epidural medication has no effect on duration of labor, study shows

Epidural analgesia – a mix of anesthetics and narcotics delivered by catheter placed close to the nerves of the spine – is the most effective method of labor pain relief. In widespread use since the 1970s, epidurals have long been thought to slow the second stage of labor – defined as beginning when the cervix is completely dilated and ending when the baby is delivered.

10 Oct 2017

NYU Dentistry awarded grant to test impact of simple treatment on cavity progression

The National Institute of Dental & Craniofacial Research, part of the National Institutes of Health, has awarded a grant that will provide funding to New York University College of Dentistry and its collaborators to test the effectiveness of silver diamine fluoride in stopping the progression of cavities in young children.

10 Oct 2017

Common acid reflux drugs linked to progression of chronic liver disease

Approximately 10 percent of the general population take a proton pump inhibitor (PPI) drug to block stomach acid secretions and relieve symptoms of frequent heartburn, acid reflux and gastroesophageal reflux disease.

10 Oct 2017

GW researchers receive NIH award to bring Zika vaccine trial to Brazil

The National Institute of Allergy and Infectious Disease of the National Institutes of Health awarded more than $2 million to a research team at the George Washington University School of Medicine and Health Sciences to facilitate a Zika vaccine trial in Brazil.

9 Oct 2017

Clinical Trial News and Research

Cascade of costs could push new gene therapy above $1 million per patient

Dietary combination transforms lethal breast cancers into highly treatable form

Portable scanner can measure limb disfigurement easily in patients with elephantiasis

Investigating new cancer therapy candidates with live-cell imaging

TGen awarded $2.5 million SU2C grant to test new method of treating pancreatic cancer

New study describes unique role of androgens in kidney cancer

Researchers develop new ‘visual biofeedback’ system for speech therapy

Phase 3 clinical trial for compound that shows promise in treatment of Rett syndrome

Higher level of tumor-infiltrating lymphocytes linked to better survival for ovarian cancer patients

Salk scientists receive $2.5 million funding to conduct pancreatic cancer clinical study

Study provides detailed characterization of neurotoxicity arising from CD19 CAR T-cell therapy

Existing drugs could help patients with rare form of bone cancer

New project to seek answers for effects of alcohol on the nervous system

Clinical trial tests frankincense as potential breast, colon cancer treatment

Allergy medication restores nervous system function in patients with chronic MS

New smell test could help improve early diagnosis of Alzheimer's, Parkinson's diseases

Epidural medication has no effect on duration of labor, study shows

NYU Dentistry awarded grant to test impact of simple treatment on cavity progression

Common acid reflux drugs linked to progression of chronic liver disease

GW researchers receive NIH award to bring Zika vaccine trial to Brazil

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