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Study reveals the benefits of using thalidomide in patients with severe arteriovenous malformations

The same properties that caused birth defects when it was given to pregnant women, the inhibition of blood vessel formation (anti-angiogenesis), have led to an interest in thalidomide's therapeutic utility in other fields.

10 Jun 2022

Study suggests the gut microbiota may be one of the factors determining the physiological inter-sex differences in pain perception

Researchers investigated whether the gut-brain axis could influence pain thresholds.

10 Jun 2022

Study investigates SARS-CoV-2 escape from nirmatrelvir

Researchers assessed SARS-CoV-2 Alpha, Delta, and Omicron variants’ resistance to nirmatrelvir, a protease inhibitor of SARS-CoV-2.

10 Jun 2022

Research reveals why many cancers are vulnerable to FDA-approved IDH1 inhibitors

A drug used to target IDH1 mutations in select cancers also appears to inhibit the wild-type form of the enzyme, under certain conditions.

9 Jun 2022

First-in-class, anti-cancer mitochondrial drug found to be effective against most carcinoma cell lines

A study of the lead agent (CPI-613) in a class of anticancer drugs undergoing Food and Drug Administration (FDA) approved clinical trials reveals that CPI-613 is effective against most carcinoma cell lines, and, used in combination, could have efficacy against reducing some tumors.

9 Jun 2022

Alternative remedy to conventional root canals would regenerate lost tooth pulp

Each year, dentists in the United States perform more than 15 million root canals on infected teeth, removing the inflamed pulp and filling the emptied canal with inert materials such as rubber and cement. What remains is a mineral shell in place of a living tooth.

9 Jun 2022

Infiltrating gliomas are shaped by genetic evolution and microenvironment, finds study

Researchers have discovered that infiltrating gliomas, a common brain and spinal cord tumor, are shaped by their genetic evolution and microenvironment, a finding that could lead to more targeted treatments.

9 Jun 2022

Research reveals how highly proliferative leukemia cells turn into normal harmless ones

A new research describes how highly proliferative leukemia cells end up becoming normal cells that no longer multiply, by changing the chemical modifications -the so-called epigenetics- of a type of its genetic material: the messenger RNA.

9 Jun 2022

KHN’s ‘What the Health?’: Taking a shot at gun control

The House passed a package of bills to restrict the availability of assault weapons to minors and other measures to curb gun violence, but talks in the Senate have yet to produce breakthroughs on what has been a legislative stalemate for years.

9 Jun 2022

Lawmaker takes on insurance companies and gets personal about his health

Scott Wiener made a startling revelation at a spring legislative committee hearing: "I was in the hospital. I experienced the most intense abdominal pain that I could even imagine."

9 Jun 2022

Study finds infertility is a modest risk factor for the development of ADHD in childhood

Researchers evaluated the risk of ADHD in offspring of infertile mothers or those receiving infertility treatment compared to offspring of mothers with unaided conception.

9 Jun 2022

People with inflammatory immune conditions had increased risk of COVID-19-related death before vaccination

People with certain inflammatory immune conditions affecting the joints, bowel and skin, such as rheumatoid arthritis, may have been more at risk of dying or needing hospital care if they got COVID-19 before vaccination compared with the general population, according to a new study published in The Lancet Rheumatology.

9 Jun 2022

Insilico Medicine plans to launch a fully automated AI-driven robotics lab for drug discovery

Insilico Medicine's end-to-end AI-driven drug discovery platform, Pharma.AI, draws its strength from the quality and quantity of its data. As Insilico scientific advisory board member and Nobel Prize laureate in chemistry Dr. Michael Levitt has said, Insilico's platform capitalizes on the ability of artificial intelligence to take vast amounts of data from many different components and find patterns and make predictions that can point the way to new life-saving medications.

9 Jun 2022

Stem cell models help determine previously unknown genetic markers of glaucoma

Stem cell models of the retina and optical nerve have been used to identify previously unknown genetic markers of glaucoma, in research jointly led by scientists from the Garvan Institute of Medical Research, the University of Melbourne, and the Centre for Eye Research Australia.

9 Jun 2022

Drugs News and Research

Study reveals the benefits of using thalidomide in patients with severe arteriovenous malformations

Study suggests the gut microbiota may be one of the factors determining the physiological inter-sex differences in pain perception

Study investigates SARS-CoV-2 escape from nirmatrelvir

Research reveals why many cancers are vulnerable to FDA-approved IDH1 inhibitors

First-in-class, anti-cancer mitochondrial drug found to be effective against most carcinoma cell lines

Alternative remedy to conventional root canals would regenerate lost tooth pulp

Infiltrating gliomas are shaped by genetic evolution and microenvironment, finds study

Research reveals how highly proliferative leukemia cells turn into normal harmless ones

KHN’s ‘What the Health?’: Taking a shot at gun control

Lawmaker takes on insurance companies and gets personal about his health

Study finds infertility is a modest risk factor for the development of ADHD in childhood

People with inflammatory immune conditions had increased risk of COVID-19-related death before vaccination

Insilico Medicine plans to launch a fully automated AI-driven robotics lab for drug discovery

Stem cell models help determine previously unknown genetic markers of glaucoma

Study describes one of the first entirely new drug delivery microencapsulation approaches in decades

Advanced microscopy techniques offer detailed insight into inner workings of cells' powerhouses

New therapeutic avoids major allergic reactions while maintaining therapeutic activity

Discovery of small protein’s structure could lead to new therapies for neurological disorders

Targeting thalamic circuits could reverse Parkinson’s symptoms in mice

Detailed genetic roadmap of glaucoma will help develop new drugs to combat the disease

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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