Infectious Diseases News and Research

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Mode of cancer cell recognition opens up new possibilities for leukaemia immunotherapy

Scientists at A*STAR's Singapore Immunology Network (SIgN) have discovered a new class of lipids in the leukaemia cells that are detected by a unique group of immune cells. By recognising the lipids, the immune cells stimulate an immune response to destroy the leukaemia cells and suppress their growth.

25 Jun 2014

Study finds link between high CD4 cell counts and reduced ischemic stroke risk in people with HIV

A 15-year study found that HIV-positive individuals had a 40 percent increased risk of ischemic stroke, however stroke rates were nearly the same for HIV-positive individuals with high CD4 cell counts as for HIV-negative subjects.

24 Jun 2014

Cubist Pharmaceuticals' SIVEXTRO receives FDA approval for treatment of ABSSSI

Cubist Pharmaceuticals, Inc. announced today the U.S. Food and Drug Administration approved SIVEXTRO (tedizolid phosphate) for the treatment of adult acute bacterial skin and skin structure infections (ABSSSI).

21 Jun 2014

Researchers adapt mathematical tool to help control malaria and other infectious diseases

A mathematical tool used by the Metropolitan Police and FBI has been adapted by researchers at Queen Mary University of London to help control outbreaks of malaria, and has the potential to target other infectious diseases.

20 Jun 2014

Researchers review effectiveness of RDTs in diagnosing visceral leishmaniasis

Researchers from the Cochrane Infectious Disease Group, co-ordinated through the editorial base in LSTM, conducted an independent review into the effectiveness of rapid diagnostic tests in diagnosing patients with visceral leishmaniasis (VL), published in The Cochrane Library today.

20 Jun 2014

HIV infection emerges among PWID in the Middle East and North Africa

HIV epidemics are emerging among people who inject drugs in several countries in the Middle East and North Africa. Though HIV infection levels were historically very low in the Middle East and North Africa, substantial levels of HIV transmission and emerging HIV epidemics have been documented among people who inject drugs in at least one-third of the countries of this region, according to findings published today in PLOS Medicine.

20 Jun 2014

ChromaDex enters into joint collaboration agreement with St. Jude Children's Research Hospital

ChromaDex Corp., an innovative natural products company that provides proprietary ingredients and science-based solutions to the dietary supplement, food and beverage, animal health, cosmetic and pharmaceutical industries, announced today it has entered into a joint collaboration agreement with St. Jude Children's Research Hospital to evaluate ChromaDex's natural product libraries.

19 Jun 2014

Review on effects of treating cholera with antimicrobial drugs

Researchers from the Cochrane Infectious Diseases Group, co-ordinated through the editorial base in LSTM, conducted an independent review of the effects of treating cholera with antimicrobial drugs, published in The Cochrane Library today.

19 Jun 2014

Debiopharm launches Phase 1 study of anti-infective agent Debio 1450

Debiopharm Group, a Swiss-based global biopharmaceutical company developing prescription drugs that target unmet medical needs as well as companion diagnostics, today announced the launch of a Phase 1 dose-escalation study of Debio 1450 (previously known as AFN-1720), a highly potent anti-infective agent that is selectively active against a large number of Staphylococcus species, including all known resistant strains such as methicillin-resistant S. aureus (MRSA) and vancomycin-intermediate S. aureus (VISA).

19 Jun 2014

Public website promotes health and science applications of 3D printing

The National Institutes of Health has launched the NIH 3D Print Exchange, a public website that enables users to share, download and edit 3D print files related to health and science.

19 Jun 2014

Janssen signs license agreement with Vertex to develop, commercialize VX-787 for influenza A treatment

Janssen Pharmaceuticals, Inc.announced today that it has entered into an exclusive license agreement with Vertex Pharmaceuticals for the worldwide development, manufacturing and commercialization of VX-787, a novel medicine in Phase II development for the treatment of influenza A.

18 Jun 2014

La Jolla Institute researchers advance work toward vaccine for heart disease

Research toward the world's first vaccine for heart disease continues to advance at the La Jolla Institute for Allergy and Immunology, with researchers demonstrating significant arterial plaque reduction in concept testing in mice.

18 Jun 2014

Entomologists develop chromosome map to find ways to prevent dengue fever, yellow fever

Virginia Tech entomologists have developed a chromosome map for about half of the genome of the mosquito Aedes agypti, the major carrier of dengue fever and yellow fever.

18 Jun 2014

Genomic study reveals striking contrasts that may aid disease prevention

Virginia Tech entomologists have developed a chromosome map for about half of the genome of the mosquito Aedes agypti, the major carrier of dengue fever and yellow fever.

17 Jun 2014

Research explores links between planet's health and human health

United Nations University will help pioneer a fresh trail in global health research, exploring links between the planet's health and human health at an institute in Kuala Lumpur generously supported by Malaysia.

17 Jun 2014

Fecal microbiota transplantation works by restoring healthy bacteria and functioning to recipient's gut

Fecal microbiota transplantation --- the process of delivering stool bacteria from a healthy donor to a patient suffering from intestinal infection with the bacterium Clostridium difficile --- works by restoring healthy bacteria and functioning to the recipient's gut, according to a study published this week in mBio-, the online open-access journal of the American Society for Microbiology.

17 Jun 2014

Discovery may lead to new treatments for common autoimmune diseases

Researchers at the University of Georgia report in the Journal of Biological Chemistry that an enzyme known as Tumor Progression Locus 2, or Tpl2, plays a key role in directing and regulating several important components of the body's immune system.

17 Jun 2014

Predicting dengue fever in Brazil: an interview with Dr. Rachel Lowe, Catalan Institute for Climate Sciences (IC3)

Dengue is a mosquito-transmitted viral infection. The disease is widespread in tropical and sub-tropical climates and most commonly found in urban areas. Around half of the world's population are now estimated to live in dengue endemic regions.

16 Jun 2014

Cepheid releases molecular test for detection of carbapenemase-producing Gram-negative bacteria

Cepheid today announced the release of Xpert® Carba-R, an on-demand molecular test for rapid and accurate detection of carbapenemase-producing Gram-negative bacteria, to be marketed as a CE IVD product under the European Directive on In Vitro Diagnostic Medical Devices.

16 Jun 2014

BRI researchers use tetramer technology to find T cells that drive rheumatoid arthritis

Researchers at Benaroya Research Institute at Virginia Mason used cutting-edge tetramer technology developed at BRI to find the T cells that drive rheumatoid arthritis (RA). "By using tetramer technology, we were able to examine whether T cells in people with rheumatoid arthritis were increased in number or were unique in other ways," says BRI Associate Director Jane Buckner, MD, who led the study with BRI Tetramer Core Laboratory Manager Eddie James, PhD.

12 Jun 2014

Infectious Diseases News and Research

Mode of cancer cell recognition opens up new possibilities for leukaemia immunotherapy

Study finds link between high CD4 cell counts and reduced ischemic stroke risk in people with HIV

Cubist Pharmaceuticals' SIVEXTRO receives FDA approval for treatment of ABSSSI

Researchers adapt mathematical tool to help control malaria and other infectious diseases

Researchers review effectiveness of RDTs in diagnosing visceral leishmaniasis

HIV infection emerges among PWID in the Middle East and North Africa

ChromaDex enters into joint collaboration agreement with St. Jude Children's Research Hospital

Review on effects of treating cholera with antimicrobial drugs

Debiopharm launches Phase 1 study of anti-infective agent Debio 1450

Public website promotes health and science applications of 3D printing

Janssen signs license agreement with Vertex to develop, commercialize VX-787 for influenza A treatment

La Jolla Institute researchers advance work toward vaccine for heart disease

Entomologists develop chromosome map to find ways to prevent dengue fever, yellow fever

Genomic study reveals striking contrasts that may aid disease prevention

Research explores links between planet's health and human health

Fecal microbiota transplantation works by restoring healthy bacteria and functioning to recipient's gut

Discovery may lead to new treatments for common autoimmune diseases

Predicting dengue fever in Brazil: an interview with Dr. Rachel Lowe, Catalan Institute for Climate Sciences (IC3)

Cepheid releases molecular test for detection of carbapenemase-producing Gram-negative bacteria

BRI researchers use tetramer technology to find T cells that drive rheumatoid arthritis

NGS for Infectious Disease Surveillance eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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