Infectious Diseases News and Research

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Expert guidance offers recommendations for hand hygiene in healthcare facilities

Expert guidance released today offers updated evidence reviews and recommendations for hand hygiene in healthcare facilities.

17 Jul 2014

Researchers discover how dengue suppresses human immune system

Scientists have discovered a new pathway the dengue virus takes to suppress the human immune system. This new knowledge deepens our understanding of the virus and could contribute to the development of more effective therapeutics.

17 Jul 2014

Expert guidance helps prioritize strategies to prevent VAP

Thousands of critically ill patients on life support develop ventilator-associated pneumonia (VAP) each year. A new document released today by a consortium of professional organizations helps prioritize strategies to prevent this potentially fatal infection.

17 Jul 2014

Investigators identify gene that underlies devastating autoinflammatory condition in children

Investigators have identified a gene that underlies a very rare but devastating autoinflammatory condition in children. Several existing drugs have shown therapeutic potential in laboratory studies, and one is currently being studied in children with the disease, which the researchers named STING-associated vasculopathy with onset in infancy (SAVI).

17 Jul 2014

Single injection of protein FGF1 enough to restore blood sugar levels

In mice with diet-induced diabetes—the equivalent of type 2 diabetes in humans—a single injection of the protein FGF1 is enough to restore blood sugar levels to a healthy range for more than two days.

17 Jul 2014

USAMRIID provides on-site laboratory support to current Ebola outbreak

Analysis of clinical samples from suspected Lassa fever cases in Sierra Leone showed that about two-thirds of the patients had been exposed to other emerging diseases, and nearly nine percent tested positive for Ebola virus.

16 Jul 2014

Research reveals why HIV remains a long-lasting infection

HIV, the virus that causes AIDS, has the ability to integrate into the human genome, making it extremely difficult to cure the infection. A new study by scientists at Seattle Children's Research Institute, University of Washington and Fred Hutchinson Cancer Research Center found that when HIV integrates into genes involved with cancer, these cells tend to reproduce to a greater extent than others HIV-infected cells.

16 Jul 2014

Cryptococcus gattii evolves as it spreads to temperate climates

Cryptococcus gattii, a virulent fungus that has invaded the Pacific Northwest is highly adaptive and warrants global "public health vigilance," according to a study by an international team led by the Translational Genomics Research Institute.

16 Jul 2014

Advanced Cell Diagnostics’ in situ hybridization technology reaches two major milestones

Advanced Cell Diagnostics Inc. (ACD), a leader in the field of molecular pathology and developer of cell and tissue-based analysis tools, has announced that its RNAscope® RNA in situ hybridization technology has reached two major milestones. In just three years, over 100 peer-reviewed papers featuring the technology have been published, and with the significant increase in use of RNAscope, ACD has now built a library of over 4000 target probes for numerous species. Probes are designed to order in under two weeks, and in just six months the library has grown by over 1500, reflecting the wide interest in ACD’s breakthrough technology.

From Advanced Cell Diagnostics 15 Jul 2014

NIH-funded study identifies genetic markers associated with eosinophilic esophagitis

Scientists funded by the National Institutes of Health have identified genetic markers associated with eosinophilic esophagitis (EoE), an inflammatory disease characterized by high levels of immune cells called eosinophils in the esophagus.

15 Jul 2014

CRISPR system involved in promoting antibiotic resistance

CRISPR, a system of genes that bacteria use to fend off viruses, is involved in promoting antibiotic resistance in Francisella novicida, a close relative of the bacterium that causes tularemia.

15 Jul 2014

HIV detected in Mississippi baby after apparent cure

In November 2013, it was reported that an infant (known as the “Mississippi baby”) had been in prolonged remission from HIV and was apparently cured. However, after 2 years without taking antiretroviral therapy and having no evidence of the virus, the child now has detectable levels of HIV.

11 Jul 2014

Mississippi baby: Infant seemingly cured of HIV has detectable levels of HIV

The child known as the "Mississippi baby"-an infant seemingly cured of HIV that was reported as a case study of a prolonged remission of HIV infection in The New England Journal of Medicine last fall-now has detectable levels of HIV after more than two years of not taking antiretroviral therapy without evidence of virus, according to the pediatric HIV specialist and researchers involved in the case.

11 Jul 2014

ACS Infectious Diseases journal highlights chemistry and collaborative research area

The American Chemical Society (ACS) announced today that Courtney Aldrich, Ph.D., will head the brand-new, web-only journal ACS Infectious Diseases as editor-in-chief. With the first issue slated for publication in January 2015, the pioneering journal will meet a growing demand for a place to publish top-notch chemistry-focused infectious diseases research.

11 Jul 2014

LA BioMed researchers launch new project to improve diabetes management

Managing diabetes is a year-round challenge for anyone living with the disease. The challenge is even greater for underserved and uninsured people who often don't have easy access to the care they need to manage their diabetes.

10 Jul 2014

Researchers address under-representation of racial/ethnic groups in HIV medical research

A New York University College of Nursing (NYUCN) research team found that a social/behavioral intervention vastly increased the number of African American and Latino individuals living with HIV/AIDS who enrolled in HIV/AIDS medical studies.

10 Jul 2014

NIAID launches CRS3123 Phase I trial to treat C. difficile infection

The National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, has launched an early-stage clinical trial of CRS3123, an investigational oral antibiotic intended to treat Clostridium difficile (C. difficile) infection.

10 Jul 2014

PTC Therapeutics initiates reimbursed expanded access program for Translarna

PTC Therapeutics, Inc. today announced the initiation of a reimbursed expanded access program (EAP). PTC's EAP program is intended to make Translarna (ataluren) available to patients before commercial availability in certain countries.

9 Jul 2014

Astellas seeks isavuconazole approval from FDA for treatment of life-threatening fungal infections

Astellas today announced it has submitted a New Drug Application (NDA) to the U.S. Food and Drug Administration seeking approval for isavuconazole for the treatment of invasive aspergillosis and invasive mucormycosis (also known as zygomycosis), life-threatening fungal infections predominantly occurring in immunocompromised patients.

9 Jul 2014

Antibiotic treatment for patients who underwent gall bladder removal does not reduce infection risk

Among patients who underwent gall bladder removal for acute calculous cholecystitis, lack of postoperative antibiotic treatment did not result in a greater incidence of infections, according to a study in the July 9 issue of JAMA.

9 Jul 2014

Infectious Diseases News and Research

Expert guidance offers recommendations for hand hygiene in healthcare facilities

Researchers discover how dengue suppresses human immune system

Expert guidance helps prioritize strategies to prevent VAP

Investigators identify gene that underlies devastating autoinflammatory condition in children

Single injection of protein FGF1 enough to restore blood sugar levels

USAMRIID provides on-site laboratory support to current Ebola outbreak

Research reveals why HIV remains a long-lasting infection

Cryptococcus gattii evolves as it spreads to temperate climates

Advanced Cell Diagnostics’ in situ hybridization technology reaches two major milestones

NIH-funded study identifies genetic markers associated with eosinophilic esophagitis

CRISPR system involved in promoting antibiotic resistance

HIV detected in Mississippi baby after apparent cure

Mississippi baby: Infant seemingly cured of HIV has detectable levels of HIV

ACS Infectious Diseases journal highlights chemistry and collaborative research area

LA BioMed researchers launch new project to improve diabetes management

Researchers address under-representation of racial/ethnic groups in HIV medical research

NIAID launches CRS3123 Phase I trial to treat C. difficile infection

PTC Therapeutics initiates reimbursed expanded access program for Translarna

Astellas seeks isavuconazole approval from FDA for treatment of life-threatening fungal infections

Antibiotic treatment for patients who underwent gall bladder removal does not reduce infection risk

Industry Focus: Infectious Diseases eBook

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

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