Clinical Trial News and Research

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Potential drug offers hope for therapy-resistant breast cancer patients

UT Southwestern Simmons Cancer Center researchers have shown that a first-in-class molecule can prevent breast cancer growth when traditional therapies stop working.

8 Aug 2017

Clinical trial shows safety, effectiveness of pre-prepared cells to treat drug-resistant viral infections

Patients who receive a hematopoietic stem cell transplant are at risk of developing potentially lethal viral infections. Some of the infections can be treated with available drugs, but they are not always effective and side effects can be significant.

8 Aug 2017

Promising brain cancer vaccine developed at Roswell Park receives orphan drug status from FDA

The U.S. Food and Drug Administration has awarded orphan drug status to a promising immunotherapy vaccine developed at Roswell Park Cancer Institute.

8 Aug 2017

New clinical trial examines potential role of drug combination therapy to eliminate LAM cells

Researchers at the University of Cincinnati begin a new clinical trial this fall, examining the potential role of a drug combination therapy to eliminate lymphangioleiomyomatosis (LAM) cells.

7 Aug 2017

Specific drug regimen taken prior to surgery reduces risk of cancer recurrence, study finds

Most cancer-related deaths are the result of post-surgical metastatic recurrence. In metastasis, cells of primary tumors travel to other parts of the body, where they often proliferate into inoperable, ultimately fatal growths.

7 Aug 2017

Diabetes drug shows promise as Parkinson’s treatment

A drug commonly used to treat diabetes could help people living with Parkinson’s disease, say researchers.

7 Aug 2017

Omeros’ OMS721 receives orphan drug designation from FDA for treatment of IgA nephropathy

Omeros Corporation today announced that OMS721 has received orphan drug designation from the U.S. Food and Drug Administration for the treatment of Immunoglobulin A (IgA) nephropathy.

4 Aug 2017

Immune ‘hotspots’ could help predict the risk of breast cancer relapse in patients, study finds

Scientists from The Institute of Cancer Research, London has developed a new test through which women at a greater risk of relapsing from breast cancer within 10 years of diagnosis can be identified.

4 Aug 2017

Researchers develop potential stem cell treatment for several lung conditions

A team of scientists from the UNC School of Medicine and North Carolina State University has developed promising research towards a possible stem cell treatment for several lung conditions, such as idiopathic pulmonary fibrosis (IPF), chronic obstructive pulmonary disease (COPD), and cystic fibrosis -- often-fatal conditions that affect tens of millions of Americans.

3 Aug 2017

Sheffield scientists discover that simple arthritis drug could help treat blood cancer sufferers

Blood cancer sufferers could be treated with a simple arthritis drug, scientists at the University of Sheffield have discovered.

3 Aug 2017

Injectable ART may have same effectiveness as standard oral treatments

Antiretroviral therapy (ART) intramuscularly administered may have the same effectiveness as current oral treatments.

3 Aug 2017

Mango intake exerts beneficial effects in progression and severity of IBD

Initial results of a study by researchers in the department of nutrition and food science at Texas A&M University in College Station show mango consumption has a positive impact on people with inflammatory bowel disease.

3 Aug 2017

SNMMI recognizes contributions to nuclear medicine and molecular imaging at 2017 annual meeting

The Society of Nuclear Medicine and Molecular Imaging (SNMMI), an international scientific and medical organization, recognized contributions to the field of nuclear medicine and molecular imaging during its 2017 Annual Meeting in Denver, Colorado. Several awards ceremonies were held to recognize the valuable role SNMMI members play in advancing the diagnosis and treatment of heart disease, cancer and neurological conditions.

2 Aug 2017

FDA gives its nod to new drug Imbruvica (Ibrutinib) for chronic Graft versus Host Disease

The U.S. Food and Drug Administration (FDA) yesterday in a press release informed about the approval of Imbruvica (ibrutinib) for the treatment of adult patients with chronic graft versus host disease (cGVHD) who have previously failed with one or more treatment. This is the first drug that the FDA has given its approval to in this disease condition.

2 Aug 2017

Researchers develop new scoring method to predict bleeding risk after stroke

A new scoring method may help predict who is at high risk of serious bleeding after a stroke, according to a study published in the August 2, 2017, online issue of Neurology, the medical journal of the American Academy of Neurology.

2 Aug 2017

GW researchers find nitric oxide-releasing nanoparticles as viable treatment for fungal skin infections

George Washington University researchers have found that topically applied nitric oxide-releasing nanoparticles (NO-np) are a viable treatment for deep fungal infections of the skin caused by dermatophytes, for which the current standard of care is treatment with systemic antifungals.

31 Jul 2017

Bringing highly potent cell therapy products to market

There are two main challenges and both relate to manufacturing. The first one is to make sure you can manufacture therapies with reasonable costs and the second one is to make sure that you can balance the capacity you need with the demands.

31 Jul 2017

Type 1 diabetes clinical trial reaches halfway point for enrollment and treatment

The Sanford Project: T-Rex Study, a Phase 2 clinical trial conducted collaboratively by Sanford Health and Caladrius Biosciences, Inc., has reached the halfway point for enrollment and treatment.

28 Jul 2017

New substance restores brain function in Alzheimer's animal model

The protein amyloid beta is believed to be the major cause of Alzheimer's disease. Substances that reduce the production of amyloid beta, such as BACE inhibitors, are therefore promising candidates for new drug treatments.

28 Jul 2017

Study examines link between RCT efficacy and real-world effectiveness of cancer therapies

Value in Health, the official journal of the International Society for Pharmacoeconomics and Outcomes Research (ISPOR), announced today the publication of new research examining the relationship between the efficacy of randomized controlled trials (RCTs) and real-world effectiveness for oncology treatments.

27 Jul 2017

Clinical Trial News and Research

Potential drug offers hope for therapy-resistant breast cancer patients

Clinical trial shows safety, effectiveness of pre-prepared cells to treat drug-resistant viral infections

Promising brain cancer vaccine developed at Roswell Park receives orphan drug status from FDA

New clinical trial examines potential role of drug combination therapy to eliminate LAM cells

Specific drug regimen taken prior to surgery reduces risk of cancer recurrence, study finds

Diabetes drug shows promise as Parkinson’s treatment

Omeros’ OMS721 receives orphan drug designation from FDA for treatment of IgA nephropathy

Immune ‘hotspots’ could help predict the risk of breast cancer relapse in patients, study finds

Researchers develop potential stem cell treatment for several lung conditions

Sheffield scientists discover that simple arthritis drug could help treat blood cancer sufferers

Injectable ART may have same effectiveness as standard oral treatments

Mango intake exerts beneficial effects in progression and severity of IBD

SNMMI recognizes contributions to nuclear medicine and molecular imaging at 2017 annual meeting

FDA gives its nod to new drug Imbruvica (Ibrutinib) for chronic Graft versus Host Disease

Researchers develop new scoring method to predict bleeding risk after stroke

GW researchers find nitric oxide-releasing nanoparticles as viable treatment for fungal skin infections

Bringing highly potent cell therapy products to market

Type 1 diabetes clinical trial reaches halfway point for enrollment and treatment

New substance restores brain function in Alzheimer's animal model

Study examines link between RCT efficacy and real-world effectiveness of cancer therapies

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