Coronavirus News and Research

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COVID-19 lockdown linked to fall in early childhood vaccination in England, a rise in Scotland

The coronavirus disease 2019 (COVID-19) pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) led to numerous and sweeping restrictions in many countries, including the UK, limiting social and economic activity.

26 Jul 2021

Study compares mRNA and adenovirus-based SARS-CoV-2 vaccines against variants of concern

In a research paper recently uploaded to the preprint server bioRxiv by Tada et al. (July 19th, 2021) the neutralizing capacity of antibodies generated by either messenger RNA (mRNA) or adenoviral vector-based vaccines against Beta, Delta, Delta plus, and Lambda variants are investigated, among others, highlighting the importance of continued SARS-CoV-2 genomic surveillance.

26 Jul 2021

SARS-CoV-2 delta variant associated with several vaccine breakthrough cases in Houston

Their findings reveal that about 58% of all new coronavirus disease 2019 (COVID-19) cases are due to the delta variant and that the prevalence of vaccine breakthrough cases associated with the variant is as high as 20%. The study is currently available on the medRxiv* preprint server while awaiting peer review.

25 Jul 2021

5.6% seroprevalence of SARS-CoV-2 antibodies in England during second wave

A recent study conducted as a part of the Real-Time Assessment of Community Transmission-2 (REACT-2) program has estimated the seroprevalence of anti-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies among adult populations in England.

25 Jul 2021

CoVizu: Making visual sense of variation in SARS-CoV-2 genomes

A new study proposes a solution to this problem in the form of a new method that can both evaluate and visually represent high numbers of SARS-CoV-2 genomes.

25 Jul 2021

CD8+ T cells show gene-dependent variation in cross-reactivity to human coronaviruses

A new study discusses how both different responses to the infection itself and to COVID-19 vaccines are likely the result of genetic differences.

25 Jul 2021

Activation of integrins by SARS-CoV-2 may be key to infection

A new study describes the key role of membrane proteins called integrins, which are present in epithelia, in the entry and propagation of SARS-CoV-2.

25 Jul 2021

Variations in human ACE2 genetics associated with coronavirus susceptibility

In a recent study, the researchers sought to understand the genetic variability in ACE2 that may contribute to inconsistent clinical outcomes of COVID-19.

25 Jul 2021

Researchers discover camelid-derived two nanobodies that target SARS-CoV-2

A new study has been published on the bioRxiv* preprint server, which has identified and characterized two RBD-targeting neutralizing nanobodies, namely, DL4 and DL28.

23 Jul 2021

Researchers use mass spectrometry to study immunogenic SARS-CoV-2 epitopes

A new study has been published on the bioRxiv* preprint server, which has used MS to identify T cell epitopes of SARS-CoV-2 conserved protein, i.e., the membrane glycol protein (MGP) and the non-structure protein-13 (NSP13).

23 Jul 2021

First dose of Pfizer-BioNTech or Oxford-AstraZeneca vaccines has strong protective effect against COVID-19 in older adults

A new study estimates vaccine effectiveness against COVID-19 mortality in England using the RDD approach.

22 Jul 2021

Efficacy of mRNA vaccine-induced memory B cells against SARS-CoV-2 variants

A new study characterizes the functional humoral immunity post-COVID-19 mRNA-based vaccination.

22 Jul 2021

Synergistic multi-antibody cocktail protects against SARS-CoV-2 in animal model

Researchers in Canada have reported the discovery of a multi-antibody cocktail that synergistically protected against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in an animal model of acute infection.

22 Jul 2021

Study in France suggests high efficacy of mRNA vaccines against SARS-CoV-2 variants of concern

A nationwide case-control study conducted in France has assessed the efficacy of mRNA-based coronavirus disease 2019 (COVID-19) vaccines against original severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its variants, including B.1.1.7, B.1.351, and P1.

22 Jul 2021

SARS-CoV-2 reprograms host chromatic network to induce immune dysfunction

A recent study conducted at the University of Texas Science Center, Houston, in the USA, has revealed that upon infection, SARS-CoV-2 alters the host chromatin architecture to suppress antiviral interferon-responsive genes and augment inflammatory genes. The study is currently available on the bioRxiv* preprint server.

22 Jul 2021

Can platelet size predict severity and mortality in COVID-19?

The ongoing COVID-19 pandemic has baffled researchers with its propensity to cause symptoms of largely unpredictable severity in the affected individuals. An exciting new study reports on the potential predictive value of platelet size in this situation. COVID-19 patients with severe disease often develop clots in vital organs, which leads to further complications. It is known that platelet size is a good indicator of activation.

22 Jul 2021

Can prior human seasonal coronavirus antibody response patterns predict SARS-CoV-2 inhibition?

A new study, recently released as a preprint on the medRxiv* server, reports the intriguing finding that the cross-neutralizing antibodies elicited by human seasonal coronaviruses (sCoVs) show varying ability to prevent binding between the SARS-CoV-2 spike antigen and its cognate receptor, the angiotensin-converting enzyme 2 (ACE2).

22 Jul 2021

Pfizer vaccine and isolation independently associated with reduced household transmission of SARS-CoV-2

Israel was among the leading proponents of COVID-19 vaccination as the way out of the current worldwide restrictions on social and economic interactions and activity. A new study, recently released as a preprint on the medRxiv* server, reports on the effects of the large-scale vaccination campaigns carried out in this country, relating to successful control of SARS-CoV-2 spread within households.

22 Jul 2021

Finding most promising targets for pan-coronavirus drugs

Safe and effective vaccines offer hope for an end to the COVID-19 pandemic. However, the possible emergence of vaccine-resistant SARS-CoV-2 variants, as well as novel coronaviruses, make finding treatments that work against all coronaviruses as important as ever.

22 Jul 2021

Wildfire smoke drives people in low-vaccinated areas indoors, raising outbreak fears

Missoula's new downtown library was teeming with people who might typically spend a Saturday afternoon hiking, biking or otherwise making the most of Montana's abundant outdoor recreation. One look at the soupy haze blanketing the city and it was clear why.

22 Jul 2021

Coronavirus News and Research

COVID-19 lockdown linked to fall in early childhood vaccination in England, a rise in Scotland

Study compares mRNA and adenovirus-based SARS-CoV-2 vaccines against variants of concern

SARS-CoV-2 delta variant associated with several vaccine breakthrough cases in Houston

5.6% seroprevalence of SARS-CoV-2 antibodies in England during second wave

CoVizu: Making visual sense of variation in SARS-CoV-2 genomes

CD8+ T cells show gene-dependent variation in cross-reactivity to human coronaviruses

Activation of integrins by SARS-CoV-2 may be key to infection

Variations in human ACE2 genetics associated with coronavirus susceptibility

Researchers discover camelid-derived two nanobodies that target SARS-CoV-2

Researchers use mass spectrometry to study immunogenic SARS-CoV-2 epitopes

First dose of Pfizer-BioNTech or Oxford-AstraZeneca vaccines has strong protective effect against COVID-19 in older adults

Efficacy of mRNA vaccine-induced memory B cells against SARS-CoV-2 variants

Synergistic multi-antibody cocktail protects against SARS-CoV-2 in animal model

Study in France suggests high efficacy of mRNA vaccines against SARS-CoV-2 variants of concern

SARS-CoV-2 reprograms host chromatic network to induce immune dysfunction

Can platelet size predict severity and mortality in COVID-19?

Can prior human seasonal coronavirus antibody response patterns predict SARS-CoV-2 inhibition?

Pfizer vaccine and isolation independently associated with reduced household transmission of SARS-CoV-2

Finding most promising targets for pan-coronavirus drugs

Wildfire smoke drives people in low-vaccinated areas indoors, raising outbreak fears

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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