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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Development and assessment of NGS-based microsatellite instability assay

The assay has a clinically relevant five-day turnaround time and can be conducted on as little as 20 ng genomic DNA with a batch size of up to forty samples in a single run.

18 Oct 2019

Researchers develop new cheap method to identify aggressive tumors

Researchers at Karolinska Institutet in Sweden have developed a new cheap method that can identify highly heterogeneous tumors that tend to be very aggressive, and therefore need to be treated more aggressively. The technique is presented in the scientific journal Nature Communications.

18 Oct 2019

Researchers uncover novel molecular clues for tumor aggression in neurofibromatosis type 1

Researchers at the Johns Hopkins Kimmel Cancer Center report that their study of tumor samples from people with the rare genetic syndrome neurofibromatosis type 1 (NF1) has uncovered novel molecular clues about which tumors are most likely to be aggressive in those with NF1

From Johns Hopkins Medicine 18 Oct 2019

Yale scientists build powerful genomic research platform to study cervical cancer

Yale Cancer Center scientists have built a powerful genomic research platform to study cervical cancer, a disease that often is untreatable if it progresses after surgery or primary chemo-radiation treatment.

17 Oct 2019

Father’s nutritional pattern affects child’s cardiovascular health

While couples often change their lifestyle in order to conceive faster, including crash diets, a new study in mice throws up the possibility that this kind of extreme dietary modification by the father might result in adverse effects on the child conceived in this manner.

17 Oct 2019

Vaping helps 50,000 cigarette smokers quit in England each year

Thousands of cigarette smokers have been able to quit in the UK by switching to e-cigarettes, also known as vapes, claims a new study published in the journal Addiction.

17 Oct 2019

Leading children's hospitals to use multi-year federal grant to scale up genomics research collaboration

With a shared vision of accelerating genomic discovery and improving patient outcomes, leaders from Boston Children's Hospital, Children's Hospital of Philadelphia, and Cincinnati Children's Hospital came together in 2015 to form the Genomics Research and Innovation Network.

17 Oct 2019

Scientists successfully create age-resistant mice with hyper-long telomeres

Researchers have shown that it is possible to extend the life of mice by generating hyper-long telomeres, without using any gene modifying technologies.

17 Oct 2019

Genes remember having low social status in the past

A new study in monkeys, published on October 14, 2019, in the Proceedings of the National Academy of Sciences, shows that organisms at the bottom of the social hierarchy live shorter lives. Moreover, they experience more sickness, and may continue to experience health problems despite moving up later. Adverse experiences of social life continue to reflect in their genes much longer than the actual experience, in the form of changes in gene expression via altered gene regulation.

16 Oct 2019

Measuring development in young children: the DNA clock

Scientists have come up with a new discovery that could transform our understanding of how childhood growth and development are measured – the DNA clock. The study, published in the Proceedings of the National Academy of Science, is the first paper to...

16 Oct 2019

New blood self-collection device quickly estimates a person's exposure to radiation

A University of Arizona College of Medicine - Phoenix research team has developed a blood self-collection device to quickly estimate a person's exposure to radiation in the event of a nuclear accident or attack.

16 Oct 2019

Lab Innovations 2019 to host new product introductions at Birmingham’s NEC

Lab Innovations, the UK’s only trade show dedicated to the laboratory industry, will see a number of new product introductions at Birmingham’s NEC, 30 & 31 October.

From Lab Innovations 16 Oct 2019

Skin's circadian clock is independent of the eyes or brain, study finds

Squids, octopuses, cuttlefish, amphibians, and chameleon lizards are among the animals that can change the color of their skin in a blink of an eye. They have photoreceptors in their skin that operate independently of their brain. The photoreceptors are part of a family of proteins known as opsins.

16 Oct 2019

Epigenetic changes can lead to development of GISTs, other cancers

Most cases of gastrointestinal stromal tumor (GIST), a type of soft-tissue cancer (sarcoma), are caused by mutations in genes that can be effectively targeted with drugs that inhibit the activity of rogue cancer-promoting enzymes.

16 Oct 2019

Drug may improve the safety of cannabis use in early pregnancy

Cannabis use during pregnancy may increase the risk of psychosis in children. Scientists have now found a drug that can reduce the effects of THC on the fetus.

16 Oct 2019

Subtle changes in mitochondrial DNA can have profound consequences for patient's health

Subtle changes in the DNA of mitochondria, the tiny power plants within cells, can have profound consequences for a patient's health.

16 Oct 2019

Scientists discover how malaria switched host from African gorillas to humans

Researchers have revealed the series of events that probably led to the world’s deadliest form of malaria being able to jump from ancient great apes to humans.

16 Oct 2019

Oxford Genetics and Sphere Fluidics announce a multi-partner collaboration

Oxford Genetics and Sphere Fluidics announce a multi-partner collaboration to expedite the development of automated microfluidic systems.

From Fluidic Sciences and Sphere Bio 16 Oct 2019

Researcher explores biological processes that cause fertility problems in humans

With significant funding from the National Institutes of Health (NIH), a researcher at The University of Texas at Arlington is investigating fundamental biological processes that lead to fertility problems in humans.

16 Oct 2019

Study shows how electrostatic interactions can be regulated to control scroll-like cochleate structures

Northwestern Engineering materials science researchers have uncovered new insights into how electrostatic interactions can be regulated to attain and control scroll-like cochleate structures, which could inform how to capture and release macromolecules in a size-selective manner as part of future drug-delivery strategies.

16 Oct 2019