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Antiviral drugs and shingles vaccines tied to lower dementia risk

New evidence links viral infections to dementia risk, suggesting vaccines and antiviral therapies may offer preventive pathways against cognitive decline.

8 Apr 2026

Xuebijing injection reduces inflammation and ferroptosis in acute lung injury

Using an LPS-induced ALI mouse model and LPS-stimulated alveolar macrophages, they found XBJ reduced inflammatory cytokine surges, preserved alveolar barrier integrity, and limited tissue injury, while probing the molecular pathways and intracellular targets underlying these benefits.

7 Apr 2026

Metformin boosts an exercise-linked metabolite and may help control weight in prostate cancer patients

Metformin raised the exercise-linked metabolite Lac-Phe in prostate cancer patients across disease stages and treatment settings, while Lac-Phe itself did not predict anticancer response. Patients in the BIMET-1 metformin arm also showed better weight management during anti-androgen therapy, highlighting a possible metabolic benefit relevant to prostate cancer care.

7 Apr 2026

What happens in the brain on psychedelics? Scientists identify a common circuit pattern

Researchers combined 11 international resting-state fMRI datasets to map how psychedelic drugs reshape brain connectivity across cortical and subcortical circuits. The mega-analysis found a shared signature of stronger coupling between transmodal association networks and unimodal or sensorimotor systems, alongside selective and variable reductions in within-network connectivity.

7 Apr 2026

Pol theta enzyme identified as key driver of cancer resilience

A cancer drug target already being investigated in clinical trials turns out to be doing something even more consequential than researchers realized.

7 Apr 2026

Newly developed smart molecules offer a safer and more precise approach to cancer care

Researchers at NYU Abu Dhabi have developed smart molecules that can both detect and treat cancer, offering a safer and more precise approach to care.

7 Apr 2026

OYE Therapeutics doses first subject in bridging study of intravenous caffeine formulation

OYE Therapeutics Inc., a clinical-stage biotechnology company developing therapies for perioperative and emergency medicine, announced that the first subject has been dosed in its scientific bridging study evaluating OYE-101.

7 Apr 2026

Smoking shrinks key brain regions while cannabis shows weaker effects

The study highlights brain changes from tobacco use and calls for more research on cannabis, as its effects on brain structure remain inadequately understood.

7 Apr 2026

New 3D printing method delivers cancer drugs directly to tumors

University of Mississippi research offers hope that cancer drug therapies packaged in 3D-printed carriers could deliver medication directly to tumors while reducing many of the side effects that cancer patients endure.

6 Apr 2026

New compounds reduce inflammation without weakening immune defense

Scripps Research scientists have developed a new class of drug compounds that reduce harmful inflammation while leaving the body's ability to fight infections intact-a long-sought goal in treating autoimmune diseases.

6 Apr 2026

How gut microbes may shape heart attack damage and recovery

This review argues that gut microbes and the metabolites they produce, especially SCFAs and TMAO, may shape how the heart responds to myocardial infarction through epigenetic pathways such as DNA methylation, histone modification, and non-coding RNAs. It also outlines potential intervention routes, including diet, probiotics, postbiotics, and metabolite-targeted therapies, while noting that much of the evidence remains translational and not yet clinically definitive.

6 Apr 2026

Mayo Clinic researchers develop experimental nanotherapy to treat aggressive brain tumors

Mayo Clinic researchers developed an experimental nanotherapy that delivers two cancer drugs directly to brain tumors, according to a study published in Communications Medicine.

6 Apr 2026

JMIR Publications' new article showcases the transformative potential of precision oncology

JMIR Publications today announced the release of a timely new article in its News and Perspectives section, showcasing the transformative potential of precision oncology.

6 Apr 2026

Organ-on-chip model advances study of sexually transmitted infections

Sexually transmitted infections (STIs) not only impact an individual's health but also result in multibillion-dollar economic losses worldwide.

3 Apr 2026

Study reveals how bacterial collagenase efficiently breaks down collagen

Collagen is an important protein that helps build the tissues of humans and animals. It is very strong because it is made of three protein strands twisted tightly together like a rope. Because of this sturdy structure, ordinary protein-cutting enzymes usually cannot break it down.

3 Apr 2026

Researchers uncover a chain of molecular events behind early brain changes in Alzheimer's

For the millions of people who carry the gene APOE4, the strongest known genetic risk factor for Alzheimer's disease, their brain activity may begin changing long before any memory problems appear.

3 Apr 2026

Semaglutide for weight loss was linked to a sharp drop in alcohol use in this case report

A 2026 case report describes a 34-year-old man with obesity and alcohol use disorder whose semaglutide treatment for weight loss was associated with a marked drop in drinking over 10 months, with his AUDIT score falling from 27 to 7 and alcohol use dropping from about 15 drinks per week to half a beer per month. The authors frame this as a promising but preliminary finding that adds to growing evidence on GLP-1 drugs and alcohol use, while also stressing that this was a single case and that better AUD screening in family medicine remains important.

2 Apr 2026

Innovative technologies transform ocular drug delivery and therapeutic outcomes

Announcing a new article publication in BIO Integration. Ocular drug delivery systems are essential for treating various eye conditions. Ocular conventional drug delivery techniques, such as eye drops (topical administration), often face challenges, like rapid drainage and low bioavailability.

2 Apr 2026

Ultrasound enables real-time monitoring and treatment of tumor vasculature

Announcing a new article publication in BIO Integration. The tumor vasculature, characterized by pathological angiogenesis and structural abnormalities, drives the progression of solid tumors by inducing hypoxia-acidosis microenvironments and therapeutic resistance.

2 Apr 2026

New drying technique stabilizes vital vaccines at room temperature

A significant challenge in global healthcare and biotechnology is the "cold chain"-the network of refrigerated storage and transport required to keep protein-based drugs, vaccines, and diagnostic tests from degrading.

2 Apr 2026

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Drugs News and Research

Antiviral drugs and shingles vaccines tied to lower dementia risk

Xuebijing injection reduces inflammation and ferroptosis in acute lung injury

Metformin boosts an exercise-linked metabolite and may help control weight in prostate cancer patients

What happens in the brain on psychedelics? Scientists identify a common circuit pattern

Pol theta enzyme identified as key driver of cancer resilience

Newly developed smart molecules offer a safer and more precise approach to cancer care

OYE Therapeutics doses first subject in bridging study of intravenous caffeine formulation

Smoking shrinks key brain regions while cannabis shows weaker effects

New 3D printing method delivers cancer drugs directly to tumors

New compounds reduce inflammation without weakening immune defense

How gut microbes may shape heart attack damage and recovery

Mayo Clinic researchers develop experimental nanotherapy to treat aggressive brain tumors

JMIR Publications' new article showcases the transformative potential of precision oncology

Organ-on-chip model advances study of sexually transmitted infections

Study reveals how bacterial collagenase efficiently breaks down collagen

Researchers uncover a chain of molecular events behind early brain changes in Alzheimer's

Semaglutide for weight loss was linked to a sharp drop in alcohol use in this case report

Innovative technologies transform ocular drug delivery and therapeutic outcomes

Ultrasound enables real-time monitoring and treatment of tumor vasculature

New drying technique stabilizes vital vaccines at room temperature

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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