Fibrosis News and Research

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Fibrosis is the growth of fibrous tissue.

Children's Colorado announces launch of the Precision Medicine Institute

Children's Hospital Colorado (Children's Colorado) today announced the launch of the Precision Medicine Institute, which will allow experts to more efficiently integrate precision medicine into care provided to patients throughout the hospital.

26 Jul 2023

Meclofenamate shows promise in treating abnormal respiratory mucus

Our respiratory system is lined with a thin fluid layer called mucus on the inside. The mucus protects us from inhaling harmful and unwanted airborne agents from germs to pollutants; it achieves this feat due to its unique gel-like texture imparted by proteins called mucins.

25 Jul 2023

Brazilian researchers identify new way to stop excessive inflammation in COVID-19

Researchers at the University of São Paulo (USP) in Brazil have identified a new class of molecules capable of stopping the excessive inflammation typical of the severe form of COVID-19 without impairing the immune response to SARS-CoV-2, the virus that causes the disease.

25 Jul 2023

Addressing research gaps: The UK's efforts to study lung cancer in never smokers

Study aimed to understand the specific needs of lung cancer in never smokers (LCINS) patients.

25 Jul 2023

New campaign aims to reduce missed or delayed diagnosis of cystic fibrosis after newborn screening

Ann & Robert H. Lurie Children's Hospital of Chicago is leading an awareness campaign that aims to reduce missed or delayed diagnosis of cystic fibrosis after newborn screening, especially in non-White infants.

24 Jul 2023

Extracellular vesicles may drive fibrosis in scleroderma

Extracellular vesicles, responsible for cell-to-cell communication, might be a driver of fibrosis in systemic sclerosis, according to a recent paper in Arthritis and Rheumatology.

21 Jul 2023

SARS-CoV-2 spike protein's role in lung injury unraveled: promising new approach uncovered

Researchers investigated the effect of SARS-CoV-2 spike (S) protein subunit 1 (S1) on the pulmonary endothelium.

19 Jul 2023

Machine learning's potential for rapid LRTI diagnosis

A team of researchers evaluated the use of prediction models in LRTI diagnosis.

17 Jul 2023

Insilico Medicine and MIKADO team up to find new treatments for cystinosis

A team led by researchers at the Mechanisms of Inherited Kidney Disorders (MIKADO) group at the University of Zurich (Zurich, Switzerland) has used Insilico Medicine's generative artificial intelligence (AI) target discovery engine, PandaOmics, to identify actionable drug targets for the lysosomal storage disease cystinosis and to validate them in preclinical models of the disease.

14 Jul 2023

The hidden factors of resistance: how pathogen diversity drives antibiotic response

Researchers aimed to understand the role of within-host microbial diversity on antimicrobial resistance.

14 Jul 2023

Macrophages may play a major role in the development of atrial fibrillation

Current treatments for atrial fibrillation (AFib), a common heart condition characterized by fast and irregular beats that can lead to stroke and heart failure, have multiple side effects and are ineffective for preventing AFib recurrence.

13 Jul 2023

Older age and certain health conditions increase risk of COVID-19 death in boosted individuals

Researchers identify patient groups at a higher risk of death due to COVID-19 among adults who received a second booster dose in England.

12 Jul 2023

New DNA repair test could revolutionize treatment for genetic disorders and cancers

A personalised test that tells how well chemotherapy, radiotherapy or gene therapy will work on individual patients is now approved for UK, US, EU and Japanese patents.

10 Jul 2023

Triple combination therapy shows promise in long-term treatment of cystic fibrosis

The mucus in the airways is not as sticky, inflammation in the lungs significantly reduced: Triple combination therapy can achieve these positive, lasting effects in patients with cystic fibrosis (CF).

7 Jul 2023

CRISPR/Cas9-based screening identifies potential therapies for non-alcoholic fatty liver disease

Activation of the NRF2 transcription factor shows promise as a potential treatment approach for non-alcoholic fatty liver disease (NAFLD), a condition associated with oxidative stress and liver damage. By screening FDA-approved drugs, researchers identified six compounds that enhanced NRF2 activity and demonstrated protective effects against oxidative stress and lipid accumulation.

3 Jul 2023

SickKids researchers discover new way to attack treatment-resistant TB infections

In the face of growing antibiotic resistance among bacterial infections, scientists at The Hospital for Sick Children (SickKids) have delved into the molecular science behind treatment-resistant tuberculosis.

28 Jun 2023

Novel biomaterials approach reveals how mechanical forces shape T cell fate

The successful campaign of adoptive T cell therapies, a type of immunotherapy in which immune T cells are collected from a patient, enhanced outside of the body, and reinfused back into the same patient, especially against blood cancers is well under way.

26 Jun 2023

Researchers identify a potential new drug for NASH-related fibrosis

Researchers at the University of California San Diego School of Medicine have led a study to examine a potential new treatment option for patients with nonalcoholic steatohepatitis (NASH)-related fibrosis.

26 Jun 2023

New hope for cystic fibrosis patients as groundbreaking treatment enters clinical trial

Clinical testing is underway for a potentially groundbreaking new treatment for cystic fibrosis. Pioneered by scientists at Carle Illinois College of Medicine at the University of Illinois Urbana-Champaign and the Carver College of Medicine at the University of Iowa in partnership with the spin-out biotechnology company, cystetic Medicines, this promising inhalable molecular prosthetic is intended to improve lung function in people with CF who cannot benefit from current therapies.

26 Jun 2023

New study warns of dangers of gene editing in human embryos

Scientists have discovered that the cells of early human embryos are often unable to repair damage to their DNA.

26 Jun 2023

Fibrosis News and Research

Further Reading

Children's Colorado announces launch of the Precision Medicine Institute

Meclofenamate shows promise in treating abnormal respiratory mucus

Brazilian researchers identify new way to stop excessive inflammation in COVID-19

Addressing research gaps: The UK's efforts to study lung cancer in never smokers

New campaign aims to reduce missed or delayed diagnosis of cystic fibrosis after newborn screening

Extracellular vesicles may drive fibrosis in scleroderma

SARS-CoV-2 spike protein's role in lung injury unraveled: promising new approach uncovered

Machine learning's potential for rapid LRTI diagnosis

Insilico Medicine and MIKADO team up to find new treatments for cystinosis

The hidden factors of resistance: how pathogen diversity drives antibiotic response

Macrophages may play a major role in the development of atrial fibrillation

Older age and certain health conditions increase risk of COVID-19 death in boosted individuals

New DNA repair test could revolutionize treatment for genetic disorders and cancers

Triple combination therapy shows promise in long-term treatment of cystic fibrosis

CRISPR/Cas9-based screening identifies potential therapies for non-alcoholic fatty liver disease

SickKids researchers discover new way to attack treatment-resistant TB infections

Novel biomaterials approach reveals how mechanical forces shape T cell fate

Researchers identify a potential new drug for NASH-related fibrosis

New hope for cystic fibrosis patients as groundbreaking treatment enters clinical trial

New study warns of dangers of gene editing in human embryos

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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