Nucleic Acid News and Research

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Proof-of-concept data for NanoString's Hyb & Seq chemistry presented at AGBT Meeting

NanoString Technologies, Inc., a provider of life science tools for translational research and molecular diagnostic products, today presented the first proof-of-concept data for its novel massively parallel single molecule sequencing chemistry, Hyb & Seq™, at the Advances in Genome Biology and Technology Meeting being held in Orlando, Florida.

From NanoString Technologies 16 Feb 2016

Wake Forest Baptist researchers develop new nanotechnology to detect disease biomarkers

Researchers at Wake Forest Baptist Medical Center have developed a new technology to detect disease biomarkers in the form of nucleic acids, the building blocks of all living organisms.

15 Feb 2016

Unlocking intrinsically disordered proteins: an interview with Peter Wright

I'm a professor in the Department of Integrative Structural and Computational Biology at The Scripps Research Institute. I have been performing NMR research on proteins for nearly 40 years.

From Bruker BioSpin - NMR, EPR and Imaging 11 Feb 2016

Novel drug shows promise against metastatic breast cancer in mouse models

12 Jan 2016

World's largest database for cancer drug discovery revolutionised by 3D techniques

THE world's largest database for cancer drug discovery has been revolutionised by adding 3D structures of faulty proteins and maps of cancer's communication networks, according to Cancer Research UK-funded research published in Nucleic Acid Research today (Monday).

4 Jan 2016

Novel drug shows promise in mouse models of human metastatic breast cancer

A doctor treating a patient with a potentially fatal metastatic breast tumor would be very pleased to find, after administering a round of treatment, that the primary tumor had undergone a change in character - from aggressive to static, and no longer shedding cells that can colonize distant organs of the body. Indeed, most patients with breast and other forms of cancer who succumb to the illness do so because of the cancer's unstoppable spread.

23 Dec 2015

Researchers report development of rapid, low-cost test for detecting TB in resource-limited areas

Tuberculosis (TB) is a highly infectious disease and a major global health problem, especially in countries with developing health care systems. Because there is no fast, easy way to detect TB, the deadly infection can spread quickly through communities. Now, a team reports in ACS Sensors the development of a rapid, sensitive and low-cost method for detecting the disease in resource-limited areas.

17 Dec 2015

The Importance of Flexibility in Spectrophotometry

News-Medical speaks to Jessica Geisler about the need for flexible spectrophotometers that can handle a range of measurement types.

From Eppendorf 1 Dec 2015

Researchers aiming to improve accuracy of current diagnostics for Leishmania infantum kinetoplast

In an article published in Small, researchers successfully applied a new qualitative and quantitative method for the detection of a DNA sequence characteristic of Leishmania infantum kinetoplast, a frequent parasite in veterinary that affects humans too.

26 Nov 2015

Researchers suggest new way to target cancer protein

For years, scientists have struggled to find a way to block a protein known to play an important role in many cancers. The protein, STAT3, acts as a transcription factor -- it performs the crucial task of helping convert DNA into the RNA instructions used to make new proteins.

19 Nov 2015

Researchers reveal how charged gold nanoparticles influence structure of DNA and RNA

Researchers at North Carolina State University have used computational modelling to shed light on precisely how charged gold nanoparticles influence the structure of DNA and RNA - which may lead to new techniques for manipulating these genetic materials.

12 Nov 2015

Bioengineers develop continuously tunable method to find and quantify DNA, RNA biomarkers

A Rice University laboratory has developed a continuously tunable method to find and quantify DNA and RNA biomarkers.

20 Oct 2015

UNITAID report examines new technologies, key market challenges to improved access to better TB diagnostics

More than 50 companies are actively developing new products to diagnose tuberculosis (TB), a disease that killed 1.5 million people in 2013, but many countries still rely on older sputum-based methods, according to a report published by UNITAID.

20 Oct 2015

Sense oligonucleotide antidote reverses actions of antisense antithrombotic drug, prevents bleeding

Researchers from Isis Pharmaceuticals (Carlsbad, CA) and Prysis Biotechnologies (Pudong, Shanghai, China) have demonstrated proof-of-concept for using a sense oligonucleotide to undo the effects of an antisense drug, an antithrombotic agent in this novel study.

14 Oct 2015

FDA permits marketing of first CSF nucleic acid-based test for detection of multiple pathogens

The U.S. Food and Drug Administration today allowed marketing of the first cerebrospinal fluid (CSF) nucleic acid-based test for simultaneous detection of multiple pathogens that can cause central nervous system infections.

12 Oct 2015

New UV-Vis spectrophotometer simplifies sample quality decisions

Life scientists who work with DNA, RNA and proteins can make educated decisions about sample suitability in experiments using a standalone, microvolume spectrophotometer for accurate quantitation and purity measurements to ensure downstream application success.

From Thermo Fisher Scientific Inc. 6 Oct 2015

Research posters support utility of EKF’s PointMan DNA enrichment technology for rapid detection of lung cancer mutations

EKF, announces two research posters supporting application of PointMan™ DNA enrichment technology, for rapid and sensitive detection of lung cancer mutations.

From EKF Diagnostics 29 Sep 2015

NYU's Jin Kim Montclare develops dual-delivery system to potentially treat multi-drug resistant cancer cells

The National Science Foundation recently funded research aimed at developing an engineered protein-lipid system that simultaneously delivers genes and drugs for the potential treatment of multi-drug resistant cancer cells. The dual-delivery system could also apply to diabetes and other conditions requiring a variety of therapeutic approaches.

11 Sep 2015

Northwestern University nanoscientist wins Raymond and Beverly Sackler Prize in Convergence Research

Northwestern University scientist Chad A. Mirkin, one of the world's leaders in nanotechnology research and its application, has been awarded the inaugural $400,000 Raymond and Beverly Sackler Prize in Convergence Research from the National Academy of Sciences.

10 Sep 2015

Quest Diagnostics receives FDA 510(k) clearance for Simplexa HSV 1 & 2 Direct molecular test

Quest Diagnostics, the world’s leading provider of diagnostic information services, today announced that its Focus Diagnostics products business has received FDA 510(k) clearance to add the genital swab claim to its Simplexa HSV 1 & 2 Direct molecular test on the Integrated Cycler.

From Quest Diagnostics 4 Sep 2015