Nephrology News and Research

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Nephrology is a branch of internal medicine and pediatrics dealing with the study of the function and diseases of the kidney.

Discovery of two important molecules that underlie the pathology of lupus, particularly kidney disease

Kidney damage associated with the autoimmune disease lupus is linked to a malfunction of immune cells that causes them to congregate in and attack the organs, researchers at UT Southwestern Medical Center have discovered in a mouse study.

22 Apr 2009

Scientists combine USB-based ultrasound probe technology with a smartphone

Computer engineers at Washington University in St. Louis are bringing the minimalist approach to medical care and computing by coupling USB-based ultrasound probe technology with a smartphone, enabling a compact, mobile computational platform and a medical imaging device that fits in the palm of a hand.

22 Apr 2009

Retooled chemotherapy agents for drug delivery may increase effectiveness

Researchers may have found a way to combine imaging with chemotherapy in a single agent for the treatment of prostate cancer, according to data presented at the American Association for Cancer Research 100th Annual Meeting 2009

22 Apr 2009

Remote or rural residence not associated with increased time to kidney transplantation

Contrary to what may be a common perception, researchers found no evidence that the likelihood of kidney transplantation is lower among remote- or rural-dwelling patients treated for kidney failure in the United States, according to a study in the April 22/29 issue of JAMA, the Journal of the American Medical Association.

22 Apr 2009

How cells control the great divide

A scientist whose work is key to understanding how cancer cells divide and spread in the body is to present advances in his latest research at a public forum to be held at the University of Leicester.

22 Apr 2009

Grapefruit juice boosts efficacy of drug rapamycin

In a small, early clinical trial, researchers at the University of Chicago Medical Center have found that combining eight ounces of grapefruit juice with the drug rapamycin can increase drug levels, allowing lower doses of the drug to be given.

20 Apr 2009

Ardea Biosciences announces positive results from a phase 1 study of lead candidate for hyperuricemia and gout

Ardea Biosciences, Inc. has announced positive results from a Phase 1 study in normal, healthy volunteers of RDEA594, its lead product candidate for the treatment of hyperuricemia and gout, and a pilot Phase 2a proof-of-concept study in gout patients of RDEA594's prodrug, RDEA806 (RDEA806 is converted to RDEA594 in the body).

20 Apr 2009

Brain metastases hijack neuron-supporting cells to resist chemotherapy

Cancer that spreads to other organs finds a particularly inviting hideout in the brain, where these metastases are usually far harder to treat than they are in other locations.

20 Apr 2009

Why do blacks with advanced kidney disease live longer than whites?

Blacks in the United States are more likely to require dialysis and develop end stage renal disease (ESRD) than whites, but they also live longer than whites once they reach later stages of kidney disease.

15 Apr 2009

Hemodialysis patients who fall at greater risk of hospitalizations and mortality

Hemodialysis (HD) patients who fall once or more have a higher risk of hospitalizations and mortality than their sure-footed counterparts, researchers at the University of Virginia Health System have reported.

15 Apr 2009

Blood transfusions after cardiac surgery may be unnecessary

Blood transfusions carried out after cardiac surgery could be unnecessary and might cause health complications for patients.

15 Apr 2009

Genetic differences influence risk of developing proteinuria

Genetic differences can influence one's risk of developing proteinuria, a condition that increases the risk of cardiovascular disease and chronic kidney disease (CKD), according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN).

15 Apr 2009

Mycophenolate mofetil may be an alternative therapy for lupus nephritis

Lupus is a rare but serious disease that mainly affects women of child-bearing age and occurs when the body's immune system goes awry, damaging a variety of organs.

15 Apr 2009

Surgical gel used to stop bleeding could confuse mammograms

Dr. Kathleen Ward noticed something odd when she examined the mammogram of a patient who had recently undergone breast cancer surgery.

14 Apr 2009

New method to estimate bleeding risk in heart attack patients

With eight basic medical facts in hand, doctors can now estimate the risk of bleeding for a patient having a heart attack.

14 Apr 2009

Medicare payments for outpatient prescription medications jumped $38 billion between 2005 and 2006

Medicare payments for outpatient prescription medications increased by more than $38 billion when comparing 2005 and 2006 data, according to the latest News and Numbers from the Agency for Healthcare Research and Quality.

13 Apr 2009

Test predicts who will develop end-stage renal disease

Measuring kidney function by assessing two different factors-glomerular filtration rate (GFR) and urinary albumin levels-helps determine which patients with chronic kidney disease (CKD) will develop end-stage renal disease (ESRD), according to a study appearing in the May 2009 issue of the Journal of the American Society Nephrology (JASN).

9 Apr 2009