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Insilico Medicine doses first patient in Phase I Trial of ISM6331 for mesothelioma

Insilico Medcine( "Insilico") , a clinical stage generative artificial intelligence (AI)-driven biotechnology company today announced the first patient has been dosed in the global multicenter Phase I Trial of ISM6331, a novel pan-TEAD inhibitor developed from Insilico's generative chemistry engine Chemistry42, for the treatment of mesothelioma and other solid tumors.

22 Jan 2025

Genomic insights and new treatment paradigms related to HER2-low breast cancer

A new review was published in Oncotarget's Volume 16 on January 20, 2025, titled "Evolving concepts in HER2-low breast cancer: Genomic insights, definitions, and treatment paradigms."

22 Jan 2025

New air-liquid interface method enhances hair follicle formation in skin organoids

For decades, creating human skin models with physiological relevance has been a persistent challenge in dermatological research.

22 Jan 2025

Diagnostic guidelines released for limbic-predominant age-related TDP-43 encephalopathy

New guidelines will help doctors identify patients with a common memory-loss syndrome that is often misdiagnosed as Alzheimer's disease in older adults.

22 Jan 2025

AI model predicts blood transfusion needs in ICU patients

Researchers at Emory University have developed a groundbreaking artificial intelligence (AI) model capable of accurately predicting the likelihood of blood transfusion in non-traumatic intensive care unit (ICU) patients.

22 Jan 2025

Study uncovers blood signatures linked to Sudden Infant Death Syndrome

New University of Virginia School of Medicine research revealing the fingerprints of Sudden Infant Death Syndrome within blood samples could open the door to simple tests to identify babies at risk.

22 Jan 2025

$2.5 Million Grant Awarded to Indiana University School of Medicine, Beckman Coulter Life Sciences to Expand Leukemia and Lymphoma Testing in Africa

Beckman Coulter and Indiana University receive a $2.5 million grant to expand leukemia and lymphoma testing in Western Kenya, boosting early diagnosis efforts.

From Beckman Coulter Life Sciences - Flow Cytometry 22 Jan 2025

Study offers insight into how senescent cells survive after cancer treatment

After treating a tumor with chemotherapy and radiotherapy, cells known as senescent cells can appear.

22 Jan 2025

Study reveals how the brain differentiates hot and cold sensations

When we touch something hot or cold, the temperature is consciously sensed. Previous studies have shown that the cortex, the outermost layer of the brain, is responsible for thermal sensations.

22 Jan 2025

Turmeric and curcumin may reduce muscle damage, inflammation after exercise

The turmeric plant, a member of the ginger family, has been used as a spice or food dye in cooking for thousands of years.

22 Jan 2025

Innovative research links biometric data to mood prediction in shift workers

The CORONA virus pandemic also brought about a pandemic of mental illness. Approximately one billion people worldwide suffer from various psychiatric conditions. Korea is one of more serious cases, with approximately 1.8 million patients exhibiting depression and anxiety disorders, and the total number of patients with clinical mental diseases has increased by 37% in five years to approximately 4.65 million.

22 Jan 2025

Breakthrough study links genetic mutations to epigenetic changes in aging

Researchers at University of California San Diego School of Medicine have published results that shed new light on an old question: what causes aging at the molecular level? Their findings, published in Nature Aging, describe a never-before-seen link between the two most accepted explanations: random genetic mutations and predictable epigenetic modifications.

21 Jan 2025