Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

Study finds LC damage and reduction in noradrenaline levels in brain are linked with MS

Researchers at the University of Illinois at Chicago have shown for the first time that damage to a particular area of the brain and a consequent reduction in noradrenaline are associated with multiple sclerosis.

13 Feb 2011

First 7 stem cell lines grown at UMMS Human Stem Cell Bank ready for global distribution

The first seven stem cell lines grown and banked at the University of Massachusetts Medical School's Human Stem Cell Bank are ready for worldwide distribution to researchers working on discovering new therapeutic treatments for diseases such as cancer, juvenile diabetes, Alzheimer's and Parkinson's, among others.

11 Feb 2011

Neuralstem updates progress of ongoing clinical trial of spinal cord stem cells in treatment of ALS

Neuralstem, Inc. updated the progress of its ongoing Phase I human clinical trial of the company's spinal cord stem cells in the treatment of ALS (amyotrophic lateral sclerosis, or Lou Gehrig's disease) at Emory University in Atlanta, Georgia.

11 Feb 2011

Scientists discover new method for early diagnosis, treatment of plaque-related diseases

UC Santa Barbara scientists have made a discovery that has the potential for use in the early diagnosis and eventual treatment of plaque-related diseases such as Alzheimer's disease and Type 2 diabetes. Their work is published in a recent issue of Nature Chemistry.

10 Feb 2011

New model of dementia care reduces emergency department visits, hospitalizations

An innovative model of dementia care developed by researchers at the Indiana University School of Medicine and the Regenstrief Institute significantly reduces emergency department visits and hospitalizations, and encourages use of medications that are not harmful to older brains. The result is improved health for older adults and their family caregivers and lower healthcare costs, according to a paper evaluating the model in real world use.

10 Feb 2011

Study finds high prevalence of HS-AGING in individuals older than 95

The population of aged persons worldwide is expanding rapidly, and it is becoming increasingly clear that there are many different diseases that affect the minds of these individuals. Researchers at the University of Kentucky are breaking new ground in the ongoing project of identifying and defining those diseases most likely to affect an aged population.

10 Feb 2011

Human-worm connection research provides insight into brain development, diseases

"Man is but a worm" was the title of a famous caricature of Darwin's ideas in Victorian England. Now, 120 years later, a molecular analysis of mysterious marine creatures unexpectedly reveals our cousins as worms, indeed.

10 Feb 2011

FDA grants Neuralstem orphan drug designation for treatment of ALS with spinal cord stem cells

Neuralstem, Inc. announced that the U.S. Food and Drug Administration's Office of Orphan Products Development has granted it orphan drug designation for the treatment of Amyotrophic Lateral Sclerosis (ALS) with its human spinal cord derived neural stem cells (NSI-566RSC), currently in a Phase I safety study to evaluate the safety of the product and the surgical route of administration in a wide range of ALS patients.

10 Feb 2011

People with memory problems may face high risk of stroke

People who have memory problems or other declines in their mental abilities may be at higher risk for stroke, according to a study released today that will be presented at the American Academy of Neurology's 63rd Annual Meeting in Honolulu April 9 to April 16, 2011.

9 Feb 2011

Johns Hopkins funds 12 research groups to launch new BSi program on cognitive disorders

The Johns Hopkins Brain Sciences Institute has funded a total of $5 million to 12 different research groups at Hopkins to launch the new Synapses, Circuits and Cognitive Disorders Program. The new BSi program aims to understand the fundamentals of brain function by focusing on the synapse — the point of contact between two nerve cells — to better understand cognitive disorders.

9 Feb 2011

Repligen third quarter total revenue increases 26% to $7,068,000

Repligen Corporation today reported results for the third quarter of fiscal year 2011, ended December 31, 2010. Total revenue for the quarter was $7,068,000 compared to total revenue of $5,617,000 for the third quarter of fiscal year 2010 ended December 31, 2009, an increase of $1,451,000 or 26%.

9 Feb 2011

CeNeRx announces FDA approval of CXB909 IND for neuroprotection and neurodegenerative disorders

CeNeRx BioPharma, Inc., a clinical-stage company developing and commercializing innovative treatments for diseases of the central nervous system (CNS), today announced FDA approval of its IND and reported the first clinical results in humans for CXB909, a novel agent that has demonstrated utility in preclinical models of neuroprotection and neurodegenerative disorders.

9 Feb 2011

Rapid detection of transiently folded single-molecule structures from 'intrinsically disordered proteins'

A team of scientists from The Scripps Research Institute and the University of California, San Diego (UCSD) have developed a novel technique to observe previously unknown details of how folded structures are formed from an intrinsically disordered protein. The insights could help scientists to better understand the mechanism of plaque formation in neurodegenerative disorders such as Parkinson's and Alzheimer's diseases.

9 Feb 2011

Two new studies report GOT may improve health outcomes of stroke patients

Much of the devastation of stroke and head trauma is due to damage caused the overproduction of a substance in the brain called glutamate. Preventing this damage has been impossible, until now, as many drugs don't cross the so-called blood-brain barrier, and those that do often don't work as intended. But a method originally devised at the Weizmann Institute of Science may, in the future, offer a way to avert such glutamate-induced harm.

9 Feb 2011

Curaxis listed on Frankfurt Stock Exchange

Patrick S. Smith, President and Chief Executive Officer of Curaxis Pharmaceutical Corp., today announced Curaxis' new listing on the Frankfurt Stock Exchange (FSE). Curaxis was at the FSE for its opening on February 8, 2011, and will trade under the symbol 8CX:GR.

9 Feb 2011

Specific gene variation linked to late-onset Alzheimer's

A new study from the Centre for Addiction and Mental Health (CAMH) has found evidence suggesting that a variation of a specific gene may play a role in late-onset Alzheimer's, the disease which accounts for over 90% of Alzheimer's cases. This innovative study has combined genetics and brain imaging to determine who may be at risk for developing late-onset Alzheimer's disease long before symptoms appear.

9 Feb 2011

Specific gene variation may play a role in late-onset Alzheimer's disease: New study

A new study from the Centre for Addiction and Mental Health has found evidence suggesting that a variation of a specific gene may play a role in late-onset Alzheimer's, the disease which accounts for over 90% of Alzheimer's cases. This innovative study has combined genetics and brain imaging to determine who may be at risk for developing late-onset Alzheimer's disease long before symptoms appear.

9 Feb 2011

Scientists develop novel technique to detect disordered protein folding

A team of scientists from The Scripps Research Institute and the University of California, San Diego have developed a novel technique to observe previously unknown details of how folded structures are formed from an intrinsically disordered protein.

9 Feb 2011

Positron anticipates expanded market opportunity for Attrius PET scanner

Positron Corporation a molecular imaging solutions company focused on nuclear cardiology, announced today that with the conditional U.S. Food and Drug Administration (FDA) approval of Eli Lilly's PET imaging agent Amyvid (florbetapir), it expects to see an expanded market opportunity for its Attrius® PET scanner.

8 Feb 2011

USPTO issues patent for Metabolon's UHPLC/MSn-based analytical platform

Metabolon, the leader in metabolomics, biomarker discovery and analysis, announced today the grant of US Patent No. 7,884,318 entitled "Systems, Methods, and Computer-Readable Medium for Determining Composition of Chemical Constituents in a Complex Mixture".

8 Feb 2011

Alzheimer's Disease News and Research

Further Reading

Study finds LC damage and reduction in noradrenaline levels in brain are linked with MS

First 7 stem cell lines grown at UMMS Human Stem Cell Bank ready for global distribution

Neuralstem updates progress of ongoing clinical trial of spinal cord stem cells in treatment of ALS

Scientists discover new method for early diagnosis, treatment of plaque-related diseases

New model of dementia care reduces emergency department visits, hospitalizations

Study finds high prevalence of HS-AGING in individuals older than 95

Human-worm connection research provides insight into brain development, diseases

FDA grants Neuralstem orphan drug designation for treatment of ALS with spinal cord stem cells

People with memory problems may face high risk of stroke

Johns Hopkins funds 12 research groups to launch new BSi program on cognitive disorders

Repligen third quarter total revenue increases 26% to $7,068,000

CeNeRx announces FDA approval of CXB909 IND for neuroprotection and neurodegenerative disorders

Rapid detection of transiently folded single-molecule structures from 'intrinsically disordered proteins'

Two new studies report GOT may improve health outcomes of stroke patients

Curaxis listed on Frankfurt Stock Exchange

Specific gene variation linked to late-onset Alzheimer's

Specific gene variation may play a role in late-onset Alzheimer's disease: New study

Scientists develop novel technique to detect disordered protein folding

Positron anticipates expanded market opportunity for Attrius PET scanner

USPTO issues patent for Metabolon's UHPLC/MSn-based analytical platform

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

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