Genome News and Research

RSS

Understanding molecular mechanisms and metabolic pathways of yeast for drug discovery

My research uses budding yeast as a tool for synthetic biology, and also in chemical and functional genomic applications. We are interested in understanding molecular mechanisms and metabolic pathways of yeast for drug discovery.

From Tecan 27 Sep 2017

MIT study sheds light on flu viruses' rapid evolution

Influenza viruses mutate rapidly, which is why flu vaccines have to be redesigned every year. A new study from MIT sheds light on just how these viruses evolve so quickly and offers a potential way to slow them down.

26 Sep 2017

Pediatric researchers discover gene variants related to aggressive form of neuroblastoma

Pediatric researchers investigating the childhood cancer neuroblastoma have identified common gene variants that raise the risk of an aggressive form of that disease. The discovery may assist doctors in better diagnosing subtypes of neuroblastoma.

25 Sep 2017

Study identifies two genes involved in invasive group A Streptococcus infections

Group A Streptococcus bacteria cause a variety of illnesses that range from mild nuisances like strep throat to life-threatening conditions including pneumonia, toxic shock syndrome and the flesh-eating disease formally known as necrotizing fasciitis.

22 Sep 2017

Genome-wide study reveals how transposons get prepared for jumping

The genome of a typical organism consists of many genes that are stringed like beads. This alignment has been surprisingly stable even over very long evolutionary periods. In addition to these genes, there are also many mobile elements, referred to as parasitic, that are spread across the whole genome and aggregated into different families according to their relatedness.

22 Sep 2017

Study may contribute to genetic understanding of high-altitude adaptation

Many research groups have recently explored human adaptation and successfully identified candidate genes to high altitude living among three major far-flung global populations: Tibetans, Ethiopians and Peruvians.

22 Sep 2017

Alternative splicing may also trigger cancer, study shows

Cancer, which is one of the leading causes of death worldwide, arises from the disruption of essential mechanisms of the normal cell life cycle, such as replication control, DNA repair and cell death.

22 Sep 2017

Global resurgence of whooping cough can be attributed to immunological failures of vaccines

The startling global resurgence of pertussis, or whooping cough, in recent years can largely be attributed to the immunological failures of acellular vaccines, Boston University School of Public Health researchers argue in a new journal article.

21 Sep 2017

Forgotten strands of DNA induce 'big bang' of immune cell development

Intricate human physiological features such as the immune system require exquisite formation and timing to develop properly. Genetic elements must be activated at just the right moment, across vast distances of genomic space.

21 Sep 2017

Scientists use genome editing to understand role of a gene key to human embryonic development

Researchers have used a genome-editing technique to elucidate the role of a gene that is key to human embryonic development.

21 Sep 2017

Study uncovers millions of previously unknown genes in human microbiome

A new study of the human microbiome- the trillions of microbial organisms that live on and within our bodies- has uncovered millions of previously unknown genes from microbial communities in the human gut, skin, mouth, and vaginal microbiome, allowing for new insights into the role these microbes play in human health and disease.

20 Sep 2017

Alcohol use may induce changes to cholesterol-regulating gene

In an analysis of the epigenomes of people and mice, researchers at Johns Hopkins Medicine and the National Institutes of Health report that drinking alcohol may induce changes to a cholesterol-regulating gene.

20 Sep 2017

Researchers identify potential gonorrhea vaccine candidates

Researchers at Oregon State University have identified a pair of proteins that show promise as the basis for a gonorrhea vaccine.

19 Sep 2017

Online toolkit helps health professionals to integrate genomics into patient care

Nurses and other health professionals looking to integrate genomics into patient care now have access to an online toolkit with more than 100 resources, part of a new website launched by the National Human Genome Research Institute.

19 Sep 2017

Houston Methodist researchers find pathway for treating diseases caused by flesh-eating bacteria

Researchers at Houston Methodist have solved a 100-year-old mystery, providing them a possible key to unlock a pathway for treating diseases caused by flesh-eating bacteria. This is timely news, given the current dangers lurking in the debris and destruction left behind by Hurricane Harvey's floodwaters that destroyed tens of thousands of homes in Texas.

19 Sep 2017

Research could lead to improvements in treating diseases caused by mutations in genes

Research carried out by academics at Northumbria University, Newcastle could lead to improvements in treating patients with diseases caused by mutations in genes, such as cancer, cystic fibrosis and potentially up to 6,000 other inherited conditions.

19 Sep 2017

Researchers discover ‘recycled’ genes in mammalian genome

One often hears about the multitude of genes we have in common with chimps, birds or other living creatures, but such comparisons are sometimes misleading. The shared percentage usually refers only to genes that encode instructions for making proteins -- while overlooking regulatory genes, which nonetheless make up a large part of the genome.

18 Sep 2017

UI scientists discover gene linked to fatal renal agenesis in children

A team led by University of Iowa researchers has identified a gene linked to rare, often fatal kidney-related birth defects.

18 Sep 2017

Scientists genetically engineer mice that display behavioral hallmarks of human bipolar disorder

Johns Hopkins researchers report they have genetically engineered mice that display many of the behavioral hallmarks of human bipolar disorder, and that the abnormal behaviors the rodents show can be reversed using well-established drug treatments for bipolar disorder, such as lithium.

18 Sep 2017

Research provides insight into how imbalance in neural precursor cells may contribute to brain diseases

Salk Institute scientists have discovered that an interaction between two key proteins helps regulate and maintain the cells that produce neurons.

15 Sep 2017

Genome News and Research

Understanding molecular mechanisms and metabolic pathways of yeast for drug discovery

MIT study sheds light on flu viruses' rapid evolution

Pediatric researchers discover gene variants related to aggressive form of neuroblastoma

Study identifies two genes involved in invasive group A Streptococcus infections

Genome-wide study reveals how transposons get prepared for jumping

Study may contribute to genetic understanding of high-altitude adaptation

Alternative splicing may also trigger cancer, study shows

Global resurgence of whooping cough can be attributed to immunological failures of vaccines

Forgotten strands of DNA induce 'big bang' of immune cell development

Scientists use genome editing to understand role of a gene key to human embryonic development

Study uncovers millions of previously unknown genes in human microbiome

Alcohol use may induce changes to cholesterol-regulating gene

Researchers identify potential gonorrhea vaccine candidates

Online toolkit helps health professionals to integrate genomics into patient care

Houston Methodist researchers find pathway for treating diseases caused by flesh-eating bacteria

Research could lead to improvements in treating diseases caused by mutations in genes

Researchers discover ‘recycled’ genes in mammalian genome

UI scientists discover gene linked to fatal renal agenesis in children

Scientists genetically engineer mice that display behavioral hallmarks of human bipolar disorder

Research provides insight into how imbalance in neural precursor cells may contribute to brain diseases

Genetics & Genomics - Second Edition eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

Latest News