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IMB researchers make breakthrough in understanding origin of aging process

Researchers at the Institute of Molecular Biology in Mainz, Germany, have made a breakthrough in understanding the origin of the aging process. They have identified that genes belonging to a process called autophagy - one of the cells most critical survival processes - promote health and fitness in young worms but drive the process of aging later in life.

15 Sep 2017

KU Leuven researchers find that humans have lost ancient defense mechanism to combat viruses

Insects and plants have an important ancient defense mechanism that helps them to fight viruses. This is encoded in their DNA. Scientists have long assumed that vertebrates - including humans - also had this same mechanism. But researchers at KU Leuven, Belgium, have found that vertebrates lost this particular asset in the course of their evolution.

15 Sep 2017

Lesser-known gene appears to play greater role in Alzheimer's and dementia-related memory decline

The notorious genetic marker of Alzheimer's disease and other forms of dementia, ApoE4, may not be a lone wolf.

15 Sep 2017

Boise State professor wins federal grant to explore basic functions of the genome

It's rare for a faculty member in any physics department to earn a federal grant administered by the National Institutes of Health, but that is exactly what Boise State assistant professor and biophysicist Matt Ferguson has done.

14 Sep 2017

Mother’s breast milk may provide metabolic boost to premature babies

The breast milk of mothers with premature babies has different amounts of microRNA than that of mothers with babies born at term, which may help premature babies catch up in growth and development, according to researchers.

14 Sep 2017

Large genetic study uncovers new risk factors for DCM, other heart conditions

With participation of the Helmholtz Zentrum München, an international research team has discovered a number of new risk factors for dilated cardiomyopathy and other heart conditions. In the largest transcriptome study to date, the researchers analyzed the RNA of transplanted hearts.

14 Sep 2017

BC Platforms introduces new resource that enables integrated analytics of genomic and clinical data

BC Platforms, a world leader in genomic data management and analysis solutions, today announces it has launched BC|RQUEST, a unique resource that enables integrated analytics of genomic and clinical data.

14 Sep 2017

Researchers find unique genetic mutation in 74-year-old man with Parkinson's disease

Mutations in the human genome may be responsible for many diseases. In the case of Parkinson's disease (PD), five locations have been the subject of recent attention. Variants of one of these locations, ACMSD (aminocarboxymuconate semialdehyde decarboxylase), may be implicated in PD, but until now, no mutations in ACMSD have been found in any PD patients.

14 Sep 2017

Researchers identify connections between toxoplasmosis and several brain disorders

More than 2 billion people – nearly one out of every three humans on earth, including about 60 million people in the United States – have a lifelong infection with the brain-dwelling parasite Toxoplasma gondii.

14 Sep 2017

Immunotherapy could help some breast cancer patients based on genetic changes in their tumors

Immunotherapy drugs could help some breast cancer patients based on the genetic changes in their tumors, researchers at the Wellcome Trust Sanger Institute and their collaborators find.

13 Sep 2017

Epigenetic changes triggered by cigarette smoke may be earliest step in lung cancer development

Scientists at the Johns Hopkins Kimmel Cancer Center say they have preliminary evidence in laboratory-grown, human airway cells that a condensed form of cigarette smoke triggers so-called "epigenetic" changes in the cells consistent with the earliest steps toward lung cancer development.

12 Sep 2017

Old lab technique helps researchers better understand circular DNA

A 50-year-old lab technique is helping researchers better understand circular DNA, a lesser-known and poorly understood cousin of the linear version commonly associated with life's genetic blueprint.

12 Sep 2017

Genome sequence cannot predict radiation resistance, say researchers

For the last two decades, researchers worldwide have been using whole genome sequencing to understand what makes cells radiation-resistant, hoping to solve an old biological mystery: why is it that one of the most radiation-resistant organisms, Deinococcus radiodurans, aka "Conan the bacterium," can survive hundreds of times more DNA damage caused by gamma rays than most other organisms? According to a study published recently in Standards of Genomic Sciences by researchers at the Uniformed Services University (USU), the amount of radiation a Deinococcus cell can survive in fact has little to do with the number and types of its DNA repair proteins.

11 Sep 2017

Researchers develop model to explore hard-to-study mutations in human genome

A team of researchers led by a bioinformatician at the University of California San Diego has developed a method to help determine whether certain hard-to-study mutations in the human genome, called short tandem repeats or microsatellites, are likely to be involved in harmful conditions.

11 Sep 2017

Study provides new insights into biologic networks involved in IBD

Scientists at the Icahn School of Medicine at Mount Sinai, Sema4, and collaborating institutions today published results of an in-depth, multi-omics approach to characterizing the immune component of inflammatory bowel disease (IBD).

11 Sep 2017

Generation Genome: the UK’s genetics revolution?

The report set out the NHS’ intentions of routinizing whole genome sequencing. It is particularly focused towards rare diseases and cancers, although conditions such as obesity, bacterial and other infections are also included.

11 Sep 2017

Machine learning and whole-genomic sequence data could predict physical traits including the face for identification study reveals

A study conducted by a team of researchers from Human Longevity, Inc. (HLI) found that whole-genome sequencing data and machine learning can be used in the prediction of individual faces and other physical traits.

8 Sep 2017

Generic drug used to increase blood flow may improve effectiveness of cancer immunotherapy

Cancer immunotherapy drugs only work for a minority of patients, but a generic drug now used to increase blood flow may be able to improve those odds, a study by Columbia University Medical Center researchers suggests.

7 Sep 2017

Myriad Genetics introduces new precision medicine tool to enhance myRisk Hereditary Cancer test

Myriad Genetics, Inc., a leader in molecular diagnostics and personalized medicine, announced today that it has launched riskScore, a new clinically validated precision medicine tool to enhance its myRisk Hereditary Cancer test. riskScore quantifies a woman's risk of developing breast cancer by combining genetic markers throughout the genome with her family and clinical history.

7 Sep 2017

New DNA sequencing technology measures effects of thousands of sequences on gene activity

When a gene is switched on, various stretches of DNA nearby act as 'control dials', influencing the level of activity and the amount of gene product that is made.

7 Sep 2017

Genome News and Research

IMB researchers make breakthrough in understanding origin of aging process

KU Leuven researchers find that humans have lost ancient defense mechanism to combat viruses

Lesser-known gene appears to play greater role in Alzheimer's and dementia-related memory decline

Boise State professor wins federal grant to explore basic functions of the genome

Mother’s breast milk may provide metabolic boost to premature babies

Large genetic study uncovers new risk factors for DCM, other heart conditions

BC Platforms introduces new resource that enables integrated analytics of genomic and clinical data

Researchers find unique genetic mutation in 74-year-old man with Parkinson's disease

Researchers identify connections between toxoplasmosis and several brain disorders

Immunotherapy could help some breast cancer patients based on genetic changes in their tumors

Epigenetic changes triggered by cigarette smoke may be earliest step in lung cancer development

Old lab technique helps researchers better understand circular DNA

Genome sequence cannot predict radiation resistance, say researchers

Researchers develop model to explore hard-to-study mutations in human genome

Study provides new insights into biologic networks involved in IBD

Generation Genome: the UK’s genetics revolution?

Machine learning and whole-genomic sequence data could predict physical traits including the face for identification study reveals

Generic drug used to increase blood flow may improve effectiveness of cancer immunotherapy

Myriad Genetics introduces new precision medicine tool to enhance myRisk Hereditary Cancer test

New DNA sequencing technology measures effects of thousands of sequences on gene activity

Genetics & Genomics - Second Edition eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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