Insulin News and Research

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Insulin is a hormone that is needed to convert glucose, starches and other food into energy needed for daily life. Insulin allows cells to use glucose for fuel and is secreted by beta cells in the islets of Langerhans. The release of insulin from the pancreas is stimulated by increased blood glucose, vagal nerve stimulation, and other factors. Insulin is obtained from various animals and available in a variety of preparations. Commercial insulin preparations differ in a number of ways, including differences in the animal species from which they are obtained; their purity, concentration, and solubility; and the time of onset and duration of their biologic action. An oral hypoglycemic agent is not a form of insulin therapy.

Extended bed rest leads to substantial muscle deterioration in older adults

Extended bed rest – often necessary during hospitalization – leads to a substantial amount of muscle deterioration in older adults, researchers at the University of Arkansas for Medical Sciences (UAMS) report in the April 25 issue of the Journal of the American Medical Association .

25 Apr 2007

Chronically ill prisoners can face great healthcare problems, but others inmates enjoy improved health

People with chronic illnesses can experience great difficulties in prison, but people such as drug addicts and the homeless may find their healthcare improves, according to a study in the latest Journal of Advanced Nursing.

25 Apr 2007

Swedish Big Brother behind lobotomies in the 1940s and 1950s

Sweden was more accepting than the U.S. in its attitude toward lobotomy in the 1940s and 1950s. A possible explanation for this may be the strength of paternalism in Sweden, that is, a greater tendency to make decisions on behalf of the patient in Swedish medical culture than in its American counterpart. This is according to Kenneth Ogren from Umea University in Sweden.

25 Apr 2007

Baxter Healthcare presents phase I inhaled insulin study results

Baxter Healthcare Corporation announced results of a Phase I study that evaluated pulmonary insulin produced with Baxter's PROMAXX microsphere technology and administered using a small, standard dry powder inhaler.

24 Apr 2007

Chronic depression or depression that worsens over time may cause diabetes in older adults

This is the first national study to suggest that depression alone -- and not lifestyle factors like being overweight ,can trigger Type 2 diabetes in adults 65 and older, a population with a high prevalence of diabetes and depression. The report will be published April 23 in Archives of Internal Medicine.

24 Apr 2007

Klotho proteins important players in future therapies for diabetes, obesity and kidney disease

A relative of the anti-aging gene Klotho helps activate a hormone that can lower blood glucose levels in fat cells of mice, making it a novel target for developing drugs to treat human obesity and diabetes, UT Southwestern Medical Center researchers have found.

24 Apr 2007

Standard long-acting insulin as good as newer medications

An older type of long-acting insulin is as effective in treating type 2 diabetes as newer and more expensive kinds, according to the results of a recent systematic review.

19 Apr 2007

Twin studies identify genes that influence human health in unexpected ways

Daniel O'Connor, M.D., Professor of Medicine and Pharmacology at the University of California, San Diego (UCSD) School of Medicine has studied about 265 twin pairs over the past few years, which has led him to some surprising discoveries.

18 Apr 2007

Treatment costs fall and quality improves when patients use self-treatment tools

Encouraging patients to become involved in providing their own care can reduce the cost and improve the quality of long-term medical treatment, say researchers from Massachusetts General Hospital and Massachusetts Institute of Technology in PLoS Medicine this week.

18 Apr 2007

Bioluminescence part of new imaging technique

CNRS scientists in collaboration have developed a new technique for the in vivo imaging of neuronal function using bioluminescence, based on a GFP-aequorin fusion protein.

18 Apr 2007

American Diabetes Association lauds Senate for passage of Stem Cell Research Enhancement Act

The American Diabetes Association today issued the following statement in response to the passage by the Senate of the "Stem Cell Research Enhancement Act" (S.5), which will accelerate stem cell research by easing existing funding restrictions and supporting research that uses embryonic stem cells, while maintaining strict ethical guidelines.

12 Apr 2007

Stem cell transplantation beneficial treatment for type 1 diabetes

A therapy that includes stem cell transplantation induced extended insulin independence in patients with type 1 diabetes mellitus, according to a preliminary study in the April 11 issue of JAMA.

11 Apr 2007

Rep. Dave Weldon comments on stem therapy and type I diabetes

In yet another advance in adult stem cell therapy, the Journal of the American Medical Association (JAMA) today released a study in which 14 of 15 Juvenile Diabetes patients demonstrated significant improvement as a result of an adult stem cell treatment.

11 Apr 2007

Most promising drugs in development for metabolic syndrome

Decision Resources, one of the world's leading research and advisory firms for pharmaceutical and healthcare issues, finds that emerging agents from Metabolex/Johnson & Johnson, Merck, Novartis, and Amylin/Eli Lilly are among the most promising drugs in development for metabolic syndrome.

11 Apr 2007

CAMR calls on U.S. Senate to pass stem cell research act

At an event on Capitol Hill today with Senators Specter (R-PA), Harkin (D-IA), Hatch (R-UT), Kennedy (D-MA) and Feinstein (D-CA), the Coalition for the Advancement of Medical Research (CAMR) called on the U.S. Senate to pass the Stem Cell Research Enhancement Act.

11 Apr 2007

Stem cells re-set the immune systems of diabetes patients

Researchers in Brazil and the U.S. have conducted an experiment which shows that stem cells can "re-set" the immune systems of diabetes patients.

10 Apr 2007

Calorie-restricted diets differing substantially in glycemic load can result in long-term weight loss

The first phase of a caloric restriction study in human subjects at the Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging (USDA HNRCA) at Tufts University found evidence suggesting that calorie-restricted diets differing substantially in glycemic load can result in comparable long-term weight loss.

10 Apr 2007

Researchers discover enzyme that is a natural tumor suppressor

Building on their 2005 discovery of an enzyme that is a natural tumor suppressor, researchers at the University of California, San Diego (UCSD) School of Medicine have now identified two variants of that enzyme which could provide new targets for therapies to treat diabetes, heart and neurological disease.

10 Apr 2007

India is poised to revolutionize biotechnology

India's health biotech firms are emerging as a major global player, with growing means and know-how to produce innovative as well as generic drugs and vaccines at costs small relative to those of giant Western firms, according to ground-breaking Canadian research.

10 Apr 2007

Weight-lifting exercises during dialysis improves muscle mass, strength, quality of life

Performing high-intensity weight-lifting exercise during dialysis sessions brings meaningful improvements in muscle mass, strength, quality of life, and other important health outcomes in patients with end-stage renal disease (ESRD), reports a study in the May Journal of the American Society of Nephrology.

5 Apr 2007

Insulin News and Research

Further Reading

Extended bed rest leads to substantial muscle deterioration in older adults

Chronically ill prisoners can face great healthcare problems, but others inmates enjoy improved health

Swedish Big Brother behind lobotomies in the 1940s and 1950s

Baxter Healthcare presents phase I inhaled insulin study results

Chronic depression or depression that worsens over time may cause diabetes in older adults

Klotho proteins important players in future therapies for diabetes, obesity and kidney disease

Standard long-acting insulin as good as newer medications

Twin studies identify genes that influence human health in unexpected ways

Treatment costs fall and quality improves when patients use self-treatment tools

Bioluminescence part of new imaging technique

American Diabetes Association lauds Senate for passage of Stem Cell Research Enhancement Act

Stem cell transplantation beneficial treatment for type 1 diabetes

Rep. Dave Weldon comments on stem therapy and type I diabetes

Most promising drugs in development for metabolic syndrome

CAMR calls on U.S. Senate to pass stem cell research act

Stem cells re-set the immune systems of diabetes patients

Calorie-restricted diets differing substantially in glycemic load can result in long-term weight loss

Researchers discover enzyme that is a natural tumor suppressor

India is poised to revolutionize biotechnology

Weight-lifting exercises during dialysis improves muscle mass, strength, quality of life

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