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Researchers develop new cocktail of drugs that shrink pancreatic tumors

Cancer is relentless and resilient. When a drug blocks a cancer cell's main survival pathway, the cell avoids the obstacle by taking different pathways or detours to save itself. This tactic is called "developing resistance," and it's one of the key challenges researchers face when seeking effective therapeutics to combat pancreatic ductal adenocarcinoma (PDA).

9 Sep 2019

Nanoparticles activated by X rays used to target deep tumours

A team of researchers from University of Texas at Arlington, University of Rhode Island and Brown University have collaborated to come up with use of nanoparticles in targeted therapy for deep seated cancers. Their success with the nanoparticples was published in a study titled, “X-ray induced photodynamic therapy with copper-cysteamine nanoparticles in mice tumors,” was published in the latest issue of the journal Proceedings of the National Academy of Sciences.

8 Sep 2019

Age affects efficacy of immunotherapy treatment for breast cancer, preclinical study reveals

Recent clinical trials have indicated that immune checkpoint blockade (ICB) therapy, which is designed to unleash a patient's immune system to attack cancer, has been revolutionary in its implications for breast cancer treatment, especially for its potential to treat patients with triple negative breast cancer.

8 Sep 2019

Researchers discover potential of antihistamines that cause death of leukemic stem cells

Ruth M. Risueño leads the Leukaemic Stem Cell group of the Josep Carreras Leukaemia Research Institute. This group investigates Acute Myeloid Leukemia and the cell population responsible for the disease spreading, persisting, and if it has been treated and overcome, reappear.

6 Sep 2019

New gold-based molecules more effective at killing cancer cells with fewer toxic side effects

Researchers have engineered gold-based molecules that target cancer cells and leave healthy cells unharmed, in a critical step towards precision cancer drugs with fewer toxic side effects.

6 Sep 2019

Groupons for medical treatment? Welcome to today’s U.S. health care

Emory University medical fellow Dr. Nicole Herbst was shocked when she saw three patients who came in with abnormal results from chest CT scans they had bought on Groupon.

6 Sep 2019

Small-cell clones in epithelial tissues organize differently than their normal-sized counterparts

Small-cell clones in proliferating epithelia – tissues that line all body surfaces – organize very differently than their normal-sized counterparts, according to a recent study from the Stowers Institute for Medical Research.

6 Sep 2019

Study confirms effectiveness of a combination therapy for advanced liver cancer

Liver cancer affects hundreds of thousands of people annually, and there are few viable therapies for the advanced stages of its most common form--hepatocellular carcinoma.

6 Sep 2019

Researchers receive $2.5 million NIH grant to study role of artemin in oral cancer pain

Researchers at New York University Oral Cancer Center were awarded a $2.5 million grant (R01CA228525) from the National Cancer Institute, part of the National Institutes of Health, to study the role of artemin in oral cancer pain and growth.

5 Sep 2019

Researchers discover a molecule that regulates tumor development in different types of cancers

Researchers from the Josep Carreras Leukemia Research Institute, discover that a non-coding region of the genome originates a key molecule for the proliferation of tumors in breast cancer and some types of sarcoma.

5 Sep 2019

New drug may enhance efficacy of chemotherapy in pancreatic cancer

One of the major obstacles in the treatment of pancreatic cancer is the 'defense wall' that is formed around the tumor.

5 Sep 2019

Common IBD drugs not linked to increased risk of serious infections in children

In a new register-based study, Swedish and Danish researchers show that common drugs for Inflammatory Bowel Disease, so-called TNF-α inhibitors, are not linked to increased risk of serious infections in children. Previous studies have shown an increased risk in corresponding adult patients.

5 Sep 2019

ASTRO guideline provides recommendations on use of radiation therapy to treat pancreatic cancer

A new clinical guideline from the American Society for Radiation Oncology provides recommendations on the use of radiation therapy to treat patients diagnosed with pancreatic cancer, including when radiation treatments are appropriate, as well as the optimal dosing, timing and fractionation for these treatments.

4 Sep 2019

Researchers develop new model to optimize radiation therapy of brain tumors

Researchers have developed a new model to optimize radiation therapy and significantly increase the number of tumour cells killed during treatment.

4 Sep 2019

Drug developed to treat metastatic pancreatic cancer may help prolong life

A drug developed by researchers at the Renaissance School of Medicine at Stony Brook University that targets enzymes involved in the development of pancreatic cancer cells is showing promise for improved treatment of metastatic pancreatic cancer.

4 Sep 2019

Breast cancer gene could be key to developing targeted therapy for hepatoblastoma

Hepatoblastoma is a rare form of liver cancer affecting just a few individuals per million. However, it is the leading cause of liver cancer in infants and young children, with most patients diagnosed before their third birthday.

4 Sep 2019

Study links FAK protein to chemotherapy resistance in ovarian cancer

Although the number of women being diagnosed and dying of ovarian cancer is declining, recurrence, drug resistance and mortality remain high for women with high-grade serous ovarian carcinoma, the most common form of epithelial ovarian cancer.

3 Sep 2019

A factor that predicts prolonged survival in brain tumor uncovered

The discoveries in the cellular and molecular biology of cancer, the development of drugs against specific genetic mutations, and the emergence of immunotherapy are allowing the cure or improvement of the quality of life and life expectancy of patients with tumors.

3 Sep 2019

Breast cancer cells can go into sleep mode and relapse in the future

Breast cancer is one of the most aggressive types of cancers in the world. It is the commonest cause of cancer death in women worldwide, and it represented about 12 percent of all new cancer cases in 2012. Current predictions and statistics suggest that both worldwide incidence of breast cancer and related mortality are on the rise. Globally, breast cancer now represents one in four of all cancers in women.

3 Sep 2019

Study reshapes the understanding of telomerase's function in normal cells

New research from the University of Maryland and the National Institutes of Health reveals a new role for the enzyme telomerase.

3 Sep 2019

Tumor News and Research

Researchers develop new cocktail of drugs that shrink pancreatic tumors

Nanoparticles activated by X rays used to target deep tumours

Age affects efficacy of immunotherapy treatment for breast cancer, preclinical study reveals

Researchers discover potential of antihistamines that cause death of leukemic stem cells

New gold-based molecules more effective at killing cancer cells with fewer toxic side effects

Groupons for medical treatment? Welcome to today’s U.S. health care

Small-cell clones in epithelial tissues organize differently than their normal-sized counterparts

Study confirms effectiveness of a combination therapy for advanced liver cancer

Researchers receive $2.5 million NIH grant to study role of artemin in oral cancer pain

Researchers discover a molecule that regulates tumor development in different types of cancers

New drug may enhance efficacy of chemotherapy in pancreatic cancer

Common IBD drugs not linked to increased risk of serious infections in children

ASTRO guideline provides recommendations on use of radiation therapy to treat pancreatic cancer

Researchers develop new model to optimize radiation therapy of brain tumors

Drug developed to treat metastatic pancreatic cancer may help prolong life

Breast cancer gene could be key to developing targeted therapy for hepatoblastoma

Study links FAK protein to chemotherapy resistance in ovarian cancer

A factor that predicts prolonged survival in brain tumor uncovered

Breast cancer cells can go into sleep mode and relapse in the future

Study reshapes the understanding of telomerase's function in normal cells

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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