Immune System News and Research

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Study receives NCI grant to explore better treatment for brain tumors in children

Children with recurrent brain tumors or newly diagnosed, particularly aggressive tumors called diffuse intrinsic pontine gliomas are being enrolled in the first study to examine the efficacy of a drug that inhibits an enzyme these tumors use to protect themselves from the child's natural immune response.

8 Oct 2019

Scientists show how protein Ikaros orchestrates fine balance to control autoimmunity

The immune system relies on B cells and their ability to make antibodies against an extremely broad range of pathogens. This broad responsiveness bears some risk, as B cells can also turn against healthy tissue - a phenomenon called autoimmunity.

8 Oct 2019

Patients' blood samples and biopsies reveal secrets of lung cancer spread

Early signs that a patient’s lung cancer may spread and become untreatable can be picked up in samples of their blood and tumor, according to a trio of papers published in Nature Medicine today (Monday).

8 Oct 2019

New protein painting technology could transform drug discovery process

George Mason University researchers have discovered the exact location where two proteins responsible for hiding cancer cells from the immune system bind.

8 Oct 2019

UVA researchers uncover key contributor to multiple sclerosis

Cells that scientists have largely ignored when studying multiple sclerosis are actually key contributors to MS development, new research from the University of Virginia School of Medicine shows.

8 Oct 2019

Cincinnati Children's receives NIH grant renewal for collaborative research into eosinophilic disorders

Cincinnati Children's Hospital Medical Center has received a 5-year, $7.57 million grant renewal from the National Institutes of Health to continue leading a consortium of organizations from around the country that will conduct clinical research into eosinophilic gastrointestinal disorders.

7 Oct 2019

Researchers study how allergens get on our nerves to drive inflammation in atopic dermatitis

Dry skin, pain, and itching... Atopic dermatitis affects the everyday lives of nearly 20% of children, and up to 5% of adults. The condition can have a significant impact on the quality of life of these patients.

7 Oct 2019

Study identifies genetic marker which could personalize treatment for Crohn's disease

The largest study ever to look at why an expensive and commonly used group of drugs fails some patients with Crohn's disease has identified a genetic marker which could individualize drug treatment.

7 Oct 2019

New device can accelerate bone regeneration in difficult cases

Within minutes of breaking a bone, the body begins to repair itself.

7 Oct 2019

Common genetic variant explains why immunotherapy often fails in Crohn's disease

The reason why a commonly used range of immunotherapy drugs is not effective in some patients with Crohn’s disease has so far not been identified, until now.

7 Oct 2019

Researchers identify an immune cell that helps keep time in the gut

As people go through their daily and nightly routines, their digestive tracts follow a routine, too: digesting food and absorbing nutrients during waking hours, and replenishing worn-out cells during sleep. Shift work and jet lag can knock sleep schedules and digestive rhythms out of whack.

4 Oct 2019

"Goldilocks" balance holds key to awakening the body's immune response to combat brain cancer

In the story of Goldilocks, a little girl tastes three different bowls of porridge to find which is not too hot, not too cold, but just the right temperature. In a study published in Advanced Therapeutics, University of Minnesota Medical School researchers report on a "Goldilocks" balance which holds the key to awakening the body's immune response to fight off brain cancer.

4 Oct 2019

New defensive mechanism against bacterial wound infections discovered

Wound inflammation which results in impaired wound healing can have serious consequences for patients. Researchers from Charité - Universitätsmedizin Berlin have discovered a new defensive mechanism which enables our skin to actively kill bacteria.

4 Oct 2019

NIH grants boost rare diseases research efforts

Of an estimated 6,500 to 7,000 known rare diseases, only a fraction - maybe 5% - have U.S. Food and Drug Administration-approved treatments.

4 Oct 2019

Australians traveling overseas urged to make sure their measles vaccinations are up to date

Measles outbreaks are happening across the globe and are reaching Australia. In the past month, there have been confirmed cases in Perth, Sydney, the Gold Coast and Cairns.

4 Oct 2019

Study explores how macrophage specialization gets disrupted by liver disease

Every tissue in the human body has an immune cell in it called a macrophage. Macrophages play important roles in the immune system's initial response to bacteria, viruses and wounds.

4 Oct 2019

New $4.5 million federal grant to make more HIV testing available in the Chicago area

More HIV testing will be available in the Chicago area, thanks to a five-year, $4.5 million federal public health grant recently awarded to the University of Chicago Medicine.

3 Oct 2019

Parkinson's disease also connected with the immune system, confirms new study

The behaviour of immune cells in the blood is so different in patients with Parkinson's disease that it advocates for a new type of supplementary medicine, which can regulate the immune system and thus inhibit the deterioration of the brain.

3 Oct 2019

Severe vomiting in early pregnancy linked to increased autism risk

A new study published in the American Journal of Perinatology shows a 53% increased risk of autism spectrum disorder in children born to women who had excessively severe nausea and vomiting in pregnancy.

3 Oct 2019

Chemical-sensing cells in the gums protect the mouth from infections

Newly discovered chemical-sensing cells in the gums protect the mouth by standing guard against infections that damage soft tissue and destroy the bone that supports the teeth, report researchers from the Monell Chemical Senses Center in an animal study published this week in Nature Communications.

3 Oct 2019

Immune System News and Research

Study receives NCI grant to explore better treatment for brain tumors in children

Scientists show how protein Ikaros orchestrates fine balance to control autoimmunity

Patients' blood samples and biopsies reveal secrets of lung cancer spread

New protein painting technology could transform drug discovery process

UVA researchers uncover key contributor to multiple sclerosis

Cincinnati Children's receives NIH grant renewal for collaborative research into eosinophilic disorders

Researchers study how allergens get on our nerves to drive inflammation in atopic dermatitis

Study identifies genetic marker which could personalize treatment for Crohn's disease

New device can accelerate bone regeneration in difficult cases

Common genetic variant explains why immunotherapy often fails in Crohn's disease

Researchers identify an immune cell that helps keep time in the gut

"Goldilocks" balance holds key to awakening the body's immune response to combat brain cancer

New defensive mechanism against bacterial wound infections discovered

NIH grants boost rare diseases research efforts

Australians traveling overseas urged to make sure their measles vaccinations are up to date

Study explores how macrophage specialization gets disrupted by liver disease

New $4.5 million federal grant to make more HIV testing available in the Chicago area

Parkinson's disease also connected with the immune system, confirms new study

Severe vomiting in early pregnancy linked to increased autism risk

Chemical-sensing cells in the gums protect the mouth from infections

Understanding the DNA Damage Response in Innate Immunity eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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