Immune System News and Research

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New circulating immune cell could help predict type 1 diabetes risk

A new Finnish study suggests that type 1 diabetes may in part be caused by a novel subset of immune cells. This is because these cells, called peripheral T helper cells, are found to circulate at a higher rate in children with type 1 diabetes of recent onset, as well as in healthy children who later develop the condition.

20 Aug 2019

Researchers develop new gene editing system that could be used for anticancer immunotherapy

Dr. Mihue Jang and her group at the Center for Theragnosis of the Korea Institute of Science and Technology announced that they have developed a new gene-editing system that could be used for anticancer immunotherapy through the simultaneous suppression of proteins that interfere with the immune system expressed on the surface of lymphoma cells and activation of cytotoxic T lymphocyte, based on the results of joint research conducted with Prof. Seokmann Hong and his group at Sejong University.

20 Aug 2019

Lipid signaling pathway may enhance T cell-mediated immunotherapy

The immune system surveils our body looking for things that don't belong, often bacteria and viruses. While cancer cells are abnormal cells that undergo unregulated cell growth, they are good at evading detection by the immune system.

19 Aug 2019

Sepsis digital alert system could save lives says NHS

According to the NHS, many lives across the country could be saved with the new and improved digital alert system for possible cases of sepsis at hospitals.

19 Aug 2019

Novel T-cell subset may have a role in development of type 1 diabetes

A study conducted at the University of Eastern Finland demonstrated that a recently described T-cell subset, so-called peripheral T helper cells, may have a role in the development of type 1 diabetes.

19 Aug 2019

UVA scientists reveal how E. coli knows to cause the worst possible infections

A pair of University of Virginia School of Medicine scientists have revealed how E. coli seeks out the most oxygen-free crevices of your colon to cause the worst infection possible.

19 Aug 2019

Study explores if fecal transplants can improve outcomes in melanoma patients

A multidisciplinary team at Lawson Health Research Institute is exploring whether fecal transplants can improve outcomes in melanoma patients treated with immunotherapy.

19 Aug 2019

Despite failed promises, stem cell advocates again want taxpayers to pony up billions

Californians voted in 2004 to shell out billions of dollars in taxpayer money to fund cutting-edge stem cell treatments.

16 Aug 2019

Researchers gain new insights into the mechanism of vaccine-induced T cell immunity

A team led by the Walter Reed Army Institute of Research has gained new insights into the mechanism of vaccine-induced T cell immunity utilizing single-cell RNA sequencing and metabolic profiling techniques.

16 Aug 2019

Removal of a critical enzyme may help cases of sepsis finds research

Scientists at the University of California San Diego School of Medicine have shown that removal of an enzyme called the PH domain Leucine-rich repeat Protein Phosphatase 1 (PHLPP1) could help laboratory mice with sepsis in a model they had created for their experiment. The study titled, “PHLPP1 counter-regulates STAT1-mediated inflammatory signalling,” was published this week in the journal eLife.

15 Aug 2019

Researchers develop new strategy to target metastases in lymph nodes

Metastasis, in which cancer cells break free from the primary tumor and form tumors at other sites, worsens the prognosis for many cancer patients.

14 Aug 2019

Mortality risk from yellow fever can be identified sooner

Approximately ten out of every 100 people who are bitten by mosquitos infected by the yellow fever virus develop symptoms of the disease. Although most infected people do not develop the disease, it is lethal to approximately 40% of those who do.

14 Aug 2019

Chlamydia vaccine shows promise after a successful clinical trial

A vaccine against the sexually transmitted infection (STI) chlamydia is now a substantial step closer to reality after successfully passing its Phase 1 clinical trial.

14 Aug 2019

Discovery of molecular mechanism behind spread of leishmania infection

Researchers from the Institut National de la Recherche Scientifique (INRS) have made a breakthrough in understanding the reason behind the virulence of leishmania parasite. The leishmania parasite is responsible for causing leishmaniasis which affects over 12 million people across the globe and is a chronic parasitic disease.

14 Aug 2019

UC San Diego researchers win $9 million funding to identify cellular cause of type 1 diabetes

University of California San Diego School of Medicine researchers have been awarded nearly $9 million to fund two multi-institutional research projects that use human pluripotent stem cells, CRISPR and human organoids to dissect beta cell defects and create a human cell model of type 1 diabetes aimed at identifying the elusive cellular actions leading to disease onset.

14 Aug 2019

Researchers identify molecular switch that impacts immune responses to viral infections

Walter and Eliza Hall Institute researchers have identified a molecular switch that impacts immune responses to viral infections, and whether or not protective antibodies are produced.

14 Aug 2019

Mice study suggests anti-cancer effect of ketogenic diet

It's well known that keeping blood glucose levels in check can help individuals avoid or manage diabetes, but new research led by biologists at The University of Texas at Dallas suggests that restricting blood glucose levels might also keep certain cancers at bay.

13 Aug 2019

Scientists step closer to an Ebola cure

The Ebola virus has killed thousands of people in Western Africa between 2014 and 2016. Recently, another outbreak in Congo emerged, killing roughly a thousand people. Now, scientists are a step closer to an Ebola cure, thanks to two new drugs that appear to be highly effective in treating people with the virus.

13 Aug 2019

Newborn mouse model yields clues to cause of devastating gut disease in anemic preemies

Physicians have long suspected that red blood cell transfusions given to premature infants with anemia may put them in danger of developing necrotizing enterocolitis, or NEC, a potentially lethal inflammatory disease of the intestines.

From Johns Hopkins Medicine 13 Aug 2019

Study provides evidence that enterovirus may be a factor in acute flaccid myelitis

A new study analyzing samples from patients with and without acute flaccid myelitis provides additional evidence for an association between the rare but often serious condition that causes muscle weakness and paralysis, and infection with non-polio enteroviruses.

13 Aug 2019

Immune System News and Research

New circulating immune cell could help predict type 1 diabetes risk

Researchers develop new gene editing system that could be used for anticancer immunotherapy

Lipid signaling pathway may enhance T cell-mediated immunotherapy

Sepsis digital alert system could save lives says NHS

Novel T-cell subset may have a role in development of type 1 diabetes

UVA scientists reveal how E. coli knows to cause the worst possible infections

Study explores if fecal transplants can improve outcomes in melanoma patients

Despite failed promises, stem cell advocates again want taxpayers to pony up billions

Researchers gain new insights into the mechanism of vaccine-induced T cell immunity

Removal of a critical enzyme may help cases of sepsis finds research

Researchers develop new strategy to target metastases in lymph nodes

Mortality risk from yellow fever can be identified sooner

Chlamydia vaccine shows promise after a successful clinical trial

Discovery of molecular mechanism behind spread of leishmania infection

UC San Diego researchers win $9 million funding to identify cellular cause of type 1 diabetes

Researchers identify molecular switch that impacts immune responses to viral infections

Mice study suggests anti-cancer effect of ketogenic diet

Scientists step closer to an Ebola cure

Newborn mouse model yields clues to cause of devastating gut disease in anemic preemies

Study provides evidence that enterovirus may be a factor in acute flaccid myelitis

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