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Nab-Paclitaxel drug combo reduces risk of breast cancer recurrence

A recent large German study has shown that a new combination therapy for breast cancer treatment leads to a lowered risk of the disease coming back. A commentary on this landmark clinical trial has been published in the latest issue of the Journal of Clinical Oncology by the researchers Masey Ross and Charles Geyer Jr. from the VCU Massey Cancer Center. The commentary was titled, “Nab-Paclitaxel: A New Standard of Care in Neoadjuvant Therapy of High-Risk Early Breast Cancer?”

27 Aug 2019

Researchers find diverse immune cell profiles, roles in breast cancer resistance to immunotherapy

In recent years it has been increasingly appreciated that immune cells within the tumor microenvironment contribute to tumor progression and, importantly, to the tumor's response to therapy.

27 Aug 2019

Gold nanoparticles shown to safely, effectively ablate low- to intermediate-grade prostate tumors

Biocompatible gold nanoparticles designed to convert near-infrared light to heat have been shown to safely and effectively ablate low- to intermediate-grade tumors within the prostate, according to a study conducted at the Icahn School of Medicine and published in the journal Proceedings of the National Academy of Sciences.

27 Aug 2019

New method maps surface protein complements on large numbers of individual exosomes

There is a growing demand for diagnostic markers for early disease detection and prognosis. Exosomes are potential biomarkers for cancer progression and neurodegenerative disease but it can be difficult to identify what tissue a specific exosome comes from.

27 Aug 2019

Genetically altering protein in colon cancer cells may enhance efficacy of chemotherapy

Colorectal cancer outcomes may improve by genetically altering an immune-regulatory protein in cancer cells, making the cells more vulnerable to chemotherapy. That's according to new Mayo Clinic research.

27 Aug 2019

Sea snail compound shows potential as new anti-cancer pharmaceutical

The remarkable ability of a small Australian sea snail to produce a colorful purple compound to protect its eggs is proving even more remarkable for its potential in a new anti-cancer pharmaceutical.

27 Aug 2019

Researchers gain new insights into types of germ cell tumors

Germ cell tumors constitute a diverse group of rare tumors, which occur in the testes, ovaries and also in other places. Some germ cell tumors exist prenatally, while others present during or after puberty. The majority is benign.

27 Aug 2019

Researchers demonstrate the effectiveness of new bladder cancer treatment

Researchers from the Molecular Cancer group at the Hospital del Mar Medical Research Institute and doctors from Hospital del Mar, have demonstrated the effectiveness of a drug for treating metastatic bladder cancer in patients who did not respond to the usual treatment.

27 Aug 2019

Ketogenic diet shown to support intestinal stem cells

Scientists have discovered that ketone bodies produced during the ketogenic diet trigger the proliferation of intestinal stem cells in adults.

26 Aug 2019

Removing tumor's protective wall could help boost the effects of cancer treatments

Scientists may have found a way to pull down the protective wall that surrounds tumors, potentially re-exposing them to the killing power of the immune system and immunotherapy treatments, according to a study part funded by Cancer Research UK and published in EBioMedicine today (Monday).

26 Aug 2019

Researchers target cancer's protective barrier

Cancer cells are notorious for their camouflage work, which enables them to escape immune targeting. Now scientists are learning how to strip away the disguise and allow the immune system to do its work, by targeting cells called myeloid-derived suppressor cells (MDSCs) that shield the tumor. This would also enhance the effectiveness of newer cancer immunotherapies like Chimeric-Antigen Receptor T cell (CAR-T).

26 Aug 2019

Researchers discover new way to stop inflammation in the lungs due to sepsis, injury

University of Calgary researchers at the Cumming School of Medicine (CSM) led by Drs. Donna Senger, PhD, Paul Kubes, PhD, and Stephen Robbins, PhD have discovered a new way to stop harmful inflammation in the lungs due to sepsis and injury.

25 Aug 2019

Frying oil consumption exaggerates colonic inflammation and colon tumor growth in mice

Foods fried in vegetable oil are popular worldwide, but research about the health effects of this cooking technique has been largely inconclusive and focused on healthy people.

25 Aug 2019

Researchers decode chain of molecules critical for growth and survival of pancreatic cancer

Researchers at Georgetown Lombardi Comprehensive Cancer Center have decoded a chain of molecules that are critical for the growth and survival of pancreatic ductal adenocarcinoma (PDAC) - the most common and also the most lethal form of pancreatic cancer.

23 Aug 2019

Head-to-head comparison of three breast cancer drugs reveals important differences

Every year, more than 250,000 women in the U.S. are diagnosed with breast cancer. When detected early, patients with the most common form--which tests positive for hormone receptors (HR+) and negative for the HER2 receptor--usually respond well to treatment.

23 Aug 2019

Sensing temperature inside cells using a fluorescent nano-thermometer

How do you know a cell has a fever? Take its temperature.

23 Aug 2019

Scientists identify unique way to treat incurable type of children's brain cancer

An international team of researchers led by Yale University, University of Iowa, and the Translational Genomics Research Institute, an affiliate of City of Hope, has discovered a new pathway that may improve success against an incurable type of children's brain cancer.

23 Aug 2019

Researchers take important step towards preventing cancer metastasis

Researchers at the Paul Scherrer Institute, together with colleagues from the pharmaceutical company F. Hoffmann-La Roche AG, have taken an important step towards the development of an agent against the metastasis of certain cancers.

23 Aug 2019

Combination therapy for rheumatoid arthritis may lead to higher remission rates

Researchers at the University of North Carolina Chapel Hill and RTI International, a nonprofit research institute, recently found that patients with early rheumatoid arthritis (RA) may see less disease activity and higher remission rates after biologic therapy plus methotrexate (MTX) rather than either treatment alone.

22 Aug 2019

Slow electrons to fight cancer

Ion beams are often used today in cancer treatment: this involves electrically charged atoms being fired at the tumor to destroy cancer cells.

22 Aug 2019

Tumor News and Research

Nab-Paclitaxel drug combo reduces risk of breast cancer recurrence

Researchers find diverse immune cell profiles, roles in breast cancer resistance to immunotherapy

Gold nanoparticles shown to safely, effectively ablate low- to intermediate-grade prostate tumors

New method maps surface protein complements on large numbers of individual exosomes

Genetically altering protein in colon cancer cells may enhance efficacy of chemotherapy

Sea snail compound shows potential as new anti-cancer pharmaceutical

Researchers gain new insights into types of germ cell tumors

Researchers demonstrate the effectiveness of new bladder cancer treatment

Ketogenic diet shown to support intestinal stem cells

Removing tumor's protective wall could help boost the effects of cancer treatments

Researchers target cancer's protective barrier

Researchers discover new way to stop inflammation in the lungs due to sepsis, injury

Frying oil consumption exaggerates colonic inflammation and colon tumor growth in mice

Researchers decode chain of molecules critical for growth and survival of pancreatic cancer

Head-to-head comparison of three breast cancer drugs reveals important differences

Sensing temperature inside cells using a fluorescent nano-thermometer

Scientists identify unique way to treat incurable type of children's brain cancer

Researchers take important step towards preventing cancer metastasis

Combination therapy for rheumatoid arthritis may lead to higher remission rates

Slow electrons to fight cancer

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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