Fibrosis News and Research

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Fibrosis is the growth of fibrous tissue.

The link between Covid-19 and Alzheimer's disease established

Renin-angiotensin system, or RAS, is a physiological mechanism essential to human body function. The SARS-CoV-2 virus causes overactivation and malfunction of this system.

21 Jun 2023

3D-printed vaginal ovules offer promising treatment for endometriosis

3D-printed vaginal ovules offer controlled release and targeted treatment, showing promise for conditions like endometriosis.

20 Jun 2023

Study reveals a link between short telomeres in ATII cells and lung fibrosis in post-COVID-19 patients

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 11, entitled, "Short telomeres in alveolar type II cells associate with lung fibrosis in post COVID-19 patients with cancer."

15 Jun 2023

Insilico announces new multimodal transformer-based aging clock for processing diverse data sets

Clinical stage generative artificial intelligence (AI)-driven drug discovery company Insilico Medicine ("Insilico") has announced a new multimodal transformer-based aging clock that is capable of processing diverse data sets and providing insights into biomarkers for aging, mapping them to genes relevant to both aging and disease, and discovering new therapeutic targets designed to slow or reverse both aging and aging-related diseases.

15 Jun 2023

Scientists identify major mechanism behind the transition between chronic and acute bacterial infections

People with weakened immune systems are at constant risk of infection. Pseudomonas aeruginosa, a common environmental bacterium, can colonize different body parts, such as the lungs, leading to persistent, chronic infections that can last a lifetime – a common occurrence in people with cystic fibrosis.

14 Jun 2023

ACMG publishes updated recommendations for CFTR carrier screening

The American College of Medical Genetics and Genomics (ACMG) has released updated recommendations for CFTR carrier screening –Updated recommendations for CFTR carrier screening: A position statement of the American College of Medical Genetics and Genomics.

13 Jun 2023

So-called “orphan” drugs earn pharmaceutical companies as much money as mainstream medicines

Drugs used to treat rare conditions are earning pharmaceutical companies almost as much as those marketed to the general public, according to a researcher at West Virginia University. Sean Tu, a College of Law professor found lucrative so-called "orphan" drugs earn manufacturing tax credits, have longer patent exclusivities and face easier Food and Drug Administration review.

12 Jun 2023

Researchers create first integrated single-cell atlas of the human lung

The largest and most comprehensive cell map of the human lung is announced in Nature Medicine today (8 June). Revealing the great diversity of cell types in the lung and key differences between health and disease, the Human Lung Cell Atlas will be a valuable resource for lung researchers.

10 Jun 2023

Insilico Medicine nominates pan-TEAD inhibitor as a potential solution for drug resistance in solid tumor patients

Insilico Medicine, a generative artificial intelligence (AI)-driven clinical-stage drug discovery company, today announced the nomination of ISM6331, a potential best-in-class pan-TEAD inhibitor, as a preclinical candidate compound (PCC) generated by Chemistry42, its proprietary generative chemistry-driven molecule design engine, targeting the Hippo pathway for the treatment of advanced solid tumors.

8 Jun 2023

Pneumothorax prevalence in COVID-19 and influenza patients

Researchers examined the occurrence and patient risk factors involved in pneumothorax.

8 Jun 2023

Unraveling the complexity of 'Long-COVID' and its impact on breathing

More than a third of COVID-19 patients experience long-lasting symptoms, known as post-COVID-19 condition or long COVID, with breathlessness being a commonly reported symptom. Pulmonary complications, such as fibrosis and thromboembolic disease, require careful assessment, and non-pharmacological interventions like pulmonary rehabilitation can help manage breathlessness.

5 Jun 2023

MFAP5, a microfibril-associated protein, unveiled as key player in scar formation and wound healing

MFAP5, a microfibril-associated protein, plays a significant role in wound healing by regulating fibroblast function, collagen deposition, and angiogenesis, suggesting its potential as a modulator of scar formation.

1 Jun 2023

Protein discovery could open up new treatment options for chronic kidney disease

Fresh insights into a protein that causes damage in kidneys and hearts could open up new treatment options for chronic kidney disease, research shows.

31 May 2023

Aggressive lung pathogen may not be prone to person-to-person transmission

A little-known bacterium - a distant cousin of the microbes that cause tuberculosis and leprosy - is emerging as a public health threat capable of causing severe lung infections among vulnerable populations, those with compromised immunity or reduced lung function.

30 May 2023

Mutated gene protects the kidney from hypertension-induced damage

A mutation that causes severe hypertension also protects the kidneys from being damaged, reports a team led by Enno Klußmann of the Max Delbrück Center and the DZHK in "Kidney International".

30 May 2023

Identifying risk biomarkers for a serious side effect of stem cell transplants

Doctors are one step closer to having a risk biomarker to alert them to which of their pediatric stem cell transplant patients are likely to experience a potentially deadly side effect called sinusoidal obstruction syndrome (SOS).

22 May 2023

Newly discovered molecule effectively destroys senescent cells

Over time, the body's cells stop working properly and begin to accumulate, which eventually leads to tissues aging.

22 May 2023

University Hospitals Birmingham partners with Qureight for lung disease research

University Hospitals Birmingham (UHB) has partnered with medical technology company, Qureight, to build more diverse artificial intelligence (AI) models that accurately reflect communities; a world-first lung disease research partnership.

22 May 2023

Combining generative AI and quantum computing to accelerate drug discovery

Insilico Medicine, a clinical stage generative artificial intelligence (AI)-driven drug discovery company, today announced that it combined two rapidly developing technologies, quantum computing and generative AI, to explore lead candidate discovery in drug development and successfully demonstrated the potential advantages of quantum generative adversarial networks in generative chemistry.

19 May 2023

Researchers identify a major stem cell variant in lungs of patients with idiopathic pulmonary fibrosis

A pair of internationally renowned stem cell cloning experts at the University of Houston is reporting their findings of variant cells in the lungs of patients with Idiopathic Pulmonary Fibrosis (IPF) which likely represent key targets in any future therapy for the condition.

17 May 2023

Fibrosis News and Research

Further Reading

The link between Covid-19 and Alzheimer's disease established

3D-printed vaginal ovules offer promising treatment for endometriosis

Study reveals a link between short telomeres in ATII cells and lung fibrosis in post-COVID-19 patients

Insilico announces new multimodal transformer-based aging clock for processing diverse data sets

Scientists identify major mechanism behind the transition between chronic and acute bacterial infections

ACMG publishes updated recommendations for CFTR carrier screening

So-called “orphan” drugs earn pharmaceutical companies as much money as mainstream medicines

Researchers create first integrated single-cell atlas of the human lung

Insilico Medicine nominates pan-TEAD inhibitor as a potential solution for drug resistance in solid tumor patients

Pneumothorax prevalence in COVID-19 and influenza patients

Unraveling the complexity of 'Long-COVID' and its impact on breathing

MFAP5, a microfibril-associated protein, unveiled as key player in scar formation and wound healing

Protein discovery could open up new treatment options for chronic kidney disease

Aggressive lung pathogen may not be prone to person-to-person transmission

Mutated gene protects the kidney from hypertension-induced damage

Identifying risk biomarkers for a serious side effect of stem cell transplants

Newly discovered molecule effectively destroys senescent cells

University Hospitals Birmingham partners with Qureight for lung disease research

Combining generative AI and quantum computing to accelerate drug discovery

Researchers identify a major stem cell variant in lungs of patients with idiopathic pulmonary fibrosis

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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