Genome News and Research

RSS

Dynamic mapping exposes hidden dynamics of gut microbiome

This study reveals how gut microbiome interactions influence E. coli colonization, using Dynamic Covariance Mapping to analyze community dynamics and stability.

14 Jul 2025

New insights into how cells silence dangerous genomic elements

An international research team led by Freiburg biologists Dr. Wenjing Qi and Prof. Ralf Baumeister has discovered how the LINE1 retrotransposon exploits a cell protein to become active itself, as occurs in tumors.

12 Jul 2025

Uncovering the hidden architecture of the genome in three dimensions

In biology textbooks and beyond, the human genome and DNA therein typically are taught in only one dimension. While it can be helpful for learners to begin with the linear presentation of how stretches of DNA form genes, this oversimplification undersells the significance of the genome's 3D structure.

12 Jul 2025

Genetic links between type 2 diabetes and subcortical brain structure revealed

Recently, the team led by Chief Physician Quan Zhang and Associate Professor Feng Liu at Tianjin Medical University General Hospital systematically evaluated the genetic associations between type 2 diabetes mellitus and subcortical brain structures using large-scale genome-wide association summary statistics and advanced statistical genetic methods.

11 Jul 2025

Natural compounds from turmeric and rhubarb show promise against superbugs in wastewater

When we're taking antibiotics, some of the dose is excreted with urine and feces and ends up in our wastewater. The presence of this low dose of antibiotic creates an opportunity for resistant bacteria to evolve.

10 Jul 2025

Breakthrough research uncovers multiple autism subtypes with unique traits

Researchers at Princeton University and the Simons Foundation have identified four clinically and biologically distinct subtypes of autism, marking a transformative step in understanding the condition's genetic underpinnings and potential for personalized care.

10 Jul 2025

The Proteoform Puzzle: Unlocking the Next Frontier

In the interview, Lloyd M. Smith discusses proteoforms, an area of research worthy of the next Human Genome Project.

From Pittcon 10 Jul 2025

Innovative genome editing approach could be the key to lifelong effective weight management

Weight-loss drugs have surged in popularity, promising rapid results with regular injections. Now, researchers from Japan report a way for the body to make its own weight-loss drugs, doing away with injections in favor of a one-time treatment.

9 Jul 2025

New study identifies four distinct autism subtypes with unique genetic signatures

Autism is classified as a 'spectrum' for a reason: Each case is different. Scientists have struggled to parse through the many ways autism can manifest, much less to link these varying observable traits (called phenotypes) to underlying genetics.

9 Jul 2025

Why vitamin B6 could raise the risk of hypoglycemia for people with diabetes

A large-scale Mendelian randomization study found no genetic evidence that vitamins A, C, or D reduce the risk of major diabetic complications. However, higher genetically predicted vitamin B6 levels were strongly associated with increased risk of diabetic hypoglycemia, warranting caution with supplementation.

8 Jul 2025

New small molecule shows promise against cutaneous HPV infections

Human papillomaviruses, or HPVs, can cause dangerous infections in the skin and mucous membranes and may lead to cancer.

8 Jul 2025

Shaping the future of psychiatry with precision medicine

In a comprehensive Genomic Press Interview published today in Genomic Psychiatry, Dr. Mirko Manchia opens up about his transformative journey from a small Sardinian city to becoming a leading voice in psychiatric pharmacogenomics, revealing how personal family experiences with mental illness sparked a lifelong quest to understand why psychiatric medications work brilliantly for some patients while failing others.

8 Jul 2025

Understanding the human brain architecture through gene coexpression analysis

In a comprehensive Genomic Press Interview published in Brain Medicine, Dr. Michael C. Oldham shares his unconventional journey from advertising executive to computational neuroscientist and his groundbreaking contributions to understanding the human brain's cellular and molecular architecture through gene coexpression analysis.

8 Jul 2025

New funding brings personalized CRISPR cures closer to children with rare diseases

Personalized CRISPR cures for children born with rare genetic diseases are now a step closer to being more widely available.

8 Jul 2025

Salivary enzyme levels rise with gene variation in diabetics

This research highlights the association between AMY1 gene copy number and salivary enzyme activity, with implications for glucose homeostasis in diabetes.

8 Jul 2025

KAIST scientists develop tool to fight drug resistance in cancer

One of the biggest obstacles in cancer treatment is drug resistance in cancer cells. Conventional efforts have focused on identifying new drug targets to eliminate these resistant cells, but such approaches can often lead to even stronger resistance.

8 Jul 2025

Synthetic Biology and the Pursuit of Living Diagnostics and Therapeutics

In this interview, Professor James J. Collins, founder of the field of Synthetic Biology, discusses his journey to founding the field of synthetic biology and the potential of living diagnostics.

From Pittcon 7 Jul 2025

Mitochondria depletion in stem cells offers insights into cellular energy and evolution

By using a genetic technique developed at UT Southwestern Medical Center that forces cells to rid themselves of mitochondria, researchers are gaining new insights into the function of these critical organelles.

7 Jul 2025

First large-scale stem cell bank created to investigate Alzheimer’s genetic risk factors

Alzheimer's disease (AD) is a common, debilitating neurodegenerative disease affecting about 10 percent of people over the age of 65 and one third of people aged 85 and above. Besides environmental factors, the genes have a strong influence on whether or not a person develops AD during their lifetime.

4 Jul 2025

New lab model brings hope for aggressive blood cancer research

Researchers working on an incurable blood cancer can now use a new lab model which could make testing potential new treatments and diagnostics easier and quicker, new research has found.

3 Jul 2025