Lymph Node News and Research

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Lymph is clear or white fluid that travels through vessels, moves within tissues and work to keep all the parts of the body clean. After passing through the channels of the lymphatic system they drain into the lymph nodes. The lymph nodes act as filters along the lymphatic system. These nodes trap germs like bacteria, viruses, toxins as well as cancer cells and ensure that these are removed from the body.

Neoprobe's Lymphoseek Phase 2 study data published in Annals of Surgical Oncology

Neoprobe Corporation (NEOP), a diversified developer of innovative oncology surgical and diagnostic products, today announced that results from a Phase II study of Lymphoseek® (Tilmanocept) have been published online in the Annals of Surgical Oncology and demonstrate the tracing agent's ability to identify tumor-draining lymph nodes in breast cancer and melanoma patients.

25 Feb 2011

Study investigates risk of dysphagia after radiotherapy treatment for head & neck cancer

At the 3rd International Conference on innovative approaches in Head and Neck Oncology (ICHNO), Dr Hanna Rahbek Mortensen and colleagues at hospitals and institutes in Denmark presented results from a large prospective trial, the DAHANCA 6 & 7 study. The study, conducted across the country, investigated risk factors for developing dysphagia (swallowing dysfunction), after undergoing radiotherapy treatment for a head & neck cancer.

25 Feb 2011

Radioactive tracing agent can identify tumor-draining sentinel nodes in breast cancer, melanoma patients

Researchers say a new kind of tracing agent is more accurate than current methods in helping identify tumor-draining sentinel lymph nodes in breast cancer and melanoma patients. That's the finding in a new study that appears in the online version of the Annals of Surgical Oncology.

25 Feb 2011

Nonsurgical methods to identify critical lymph nodes in patients with breast cancer

Researchers at the University of California, San Diego are developing nonsurgical methods for identifying critical lymph nodes to help doctors determine courses of treatment for breast cancer patients.

24 Feb 2011

Advancell announces positive results from Acadra clinical study in Chronic Lymphocytic Leukemia

ADVANCELL, an emerging biopharmaceutical company, today announced positive results from a clinical study conducted with Acadra (Acadesine) in Chronic Lymphocytic Leukemia patients resistant to current therapies. The company also announced promising non-clinical results in Multiple Myeloma (MM), Mantle Cell Lymphoma (MCL) and other lymphoproliferative disorders. Synergism of Acadra in combination with current treatment in these indications has been demonstrated.

21 Feb 2011

Viewpoints: Arizona's waiver; next gen's 'different' Medicare?; individual mandate's constitutionality

There may be no federal obstacles to cutting 250,000 people out of AHCCCS, part of Gov. Jan Brewer's budget proposal. But there are compelling reasons to avoid such a drastic step if at all possible. And it's possible.

17 Feb 2011

1000th clinical trial added to Cancer Research UK's patient information website

Cancer Research UK has added the 1000th clinical trial to its award winning patient information website, CancerHelp UK, on the 10th anniversary of the launch of its clinical trials database today.

17 Feb 2011

Two researchers receive Brupbacher Prize for Cancer Research 2011

Today, the Charles Rodolphe Brupbacher Prize for Cancer Research 2011 goes to two researchers who have contributed to better understanding of the genetics underlying the growth of tumors.

17 Feb 2011

Cook Medical launches new histology needle for endoscopic ultrasound

A new histology needle for endoscopic ultrasound (EUS) from Cook Medical is now on the market, giving physicians the ability to retrieve tissue samples from hard-to-reach regions within or adjacent to the GI tract with a minimally invasive procedure.

17 Feb 2011

Novel molecular approach using biomarker can predict colorectal cancer staging, recurrence

A quantitative, molecular analysis of lymph nodes in patients deemed colorectal cancer-free was found to be an effective predictor of recurrence, according to a study from researchers at the Kimmel Cancer Center at Jefferson and published online Feb 9. in Clinical Cancer Research.

16 Feb 2011

State Roundup: Calif. adult day care; S.C.'s budget cuts; Minn. 'boomer bust'

As Gov. Jerry Brown has proposed slashing government aid for poor people, he argues that California still provides more generous benefits than many other states. … State-by-state comparisons are complicated. ... While California pays health costs for a larger share of its population, it spends less per person. It reimburses health care providers less and covers a younger, healthier group of people (Yamamura, 2/14).

14 Feb 2011

Neoprobe achieves accrual goal in Lymphoseek Phase 3 study in breast cancer/melanoma

Neoprobe Corporation, a diversified developer of innovative oncology surgical and diagnostic products, today announced that a multi-center Phase 3 study of Lymphoseek® has enrolled clinical subjects to achieve the minimum analysis goal of 196 lymph nodes, the study's primary accrual objective.

14 Feb 2011

Vaccinating through salivary glands may provide protection against wide range of diseases

If you don't like shots or needles, you're in luck. New research published online in The FASEB Journal gives the development of new oral vaccinations a shot in the arm thanks to discoveries involving the salivary glands of mice. In addition, this research report also offers a tantalizing glimpse of vaccines that could prevent infection at mucosal surfaces, even if direct injections into the body fail to cause immunity. This technique may be effective for a wide range of diseases from influenza to cholera.

11 Feb 2011

Photodynamic therapy could be useful in eradicating tumor-associated lymphatic vessels

Tumor cells have several routes that enable them to move from the primary tumor to distant tissues, a process called metastasis. It is metastasis of the primary tumor that kills most cancer patients. One of the least studied routes of metastasis is the lymphatic system. Many tumors produce factors that promote the formation of new lymphatic vessels (lymphangiogenesis).

10 Feb 2011

Study finds breast cancer patients do not benefit from axillary lymph node dissection

Among patients with early-stage breast cancer that had spread to a nearby lymph node and who received treatment that included lumpectomy and radiation therapy, women who just had the sentinel lymph node removed did not have worse survival than women who had more extensive axillary lymph node dissection, according to a study in the February 9 issue of JAMA.

9 Feb 2011

Four-gene/protein signature more accurately predicts metastatic prostate cancer

Prostate tumors that carry a "signature" of four molecular markers have the potential to become dangerously metastatic if not treated aggressively, researchers at Dana-Farber Cancer Institute report in a study published online today by the journal Nature. The discovery lays the groundwork for the first gene-based test for determining whether a man's prostate cancer is likely to remain dormant within the prostate gland, or spread lethally to other parts of the body.

3 Feb 2011

Microbubble contrast- enhanced ultrasound improves identification of sentinel lymph node in breast biopsies

Using "microbubbles" and ultrasound can mean more targeted breast biopsies for patients with early breast cancer, helping to determine treatment and possibly saving those patients from undergoing a second breast cancer surgery, a new study in shows.

2 Feb 2011

Surge of mosquito borne disease in South Australia following wet weather

Rising water in the Murray River has caused a surge in mosquito-borne infections in South Australia. The water is rising in the Murray in SA as floodwaters move downstream from the eastern states.

2 Feb 2011

FDA approves 'Cornell Dots' for first clinical trial in humans to diagnose cancer

"Cornell Dots" - brightly glowing nanoparticles - may soon be used to light up cancer cells to aid in diagnosing and treating cancer. The U.S. Food and Drug Administration has approved the first clinical trial in humans of the new technology.

1 Feb 2011

FDA approves ultrasmall silica inorganic nanoparticle INDA for targeted molecular imaging of cancer

Researchers at Memorial Sloan-Kettering Cancer Center's Nanotechnology Center, along with collaborators at Cornell University and Hybrid Silica Technologies, have received approval for their first Investigational New Drug Application from the US Food and Drug Administration for an ultrasmall silica inorganic nanoparticle platform for targeted molecular imaging of cancer, which may be useful for cancer treatment in the future.

31 Jan 2011

Lymph Node News and Research

Further Reading

Neoprobe's Lymphoseek Phase 2 study data published in Annals of Surgical Oncology

Study investigates risk of dysphagia after radiotherapy treatment for head & neck cancer

Radioactive tracing agent can identify tumor-draining sentinel nodes in breast cancer, melanoma patients

Nonsurgical methods to identify critical lymph nodes in patients with breast cancer

Advancell announces positive results from Acadra clinical study in Chronic Lymphocytic Leukemia

Viewpoints: Arizona's waiver; next gen's 'different' Medicare?; individual mandate's constitutionality

1000th clinical trial added to Cancer Research UK's patient information website

Two researchers receive Brupbacher Prize for Cancer Research 2011

Cook Medical launches new histology needle for endoscopic ultrasound

Novel molecular approach using biomarker can predict colorectal cancer staging, recurrence

State Roundup: Calif. adult day care; S.C.'s budget cuts; Minn. 'boomer bust'

Neoprobe achieves accrual goal in Lymphoseek Phase 3 study in breast cancer/melanoma

Vaccinating through salivary glands may provide protection against wide range of diseases

Photodynamic therapy could be useful in eradicating tumor-associated lymphatic vessels

Study finds breast cancer patients do not benefit from axillary lymph node dissection

Four-gene/protein signature more accurately predicts metastatic prostate cancer

Microbubble contrast- enhanced ultrasound improves identification of sentinel lymph node in breast biopsies

Surge of mosquito borne disease in South Australia following wet weather

FDA approves 'Cornell Dots' for first clinical trial in humans to diagnose cancer

FDA approves ultrasmall silica inorganic nanoparticle INDA for targeted molecular imaging of cancer

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