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A microbiota-driven mechanism underlies severity of leishmaniasis infection

In a recent study posed to the medRxiv* preprint server, researchers in Brazil and the United States investigated the probable impact of the skin microbiome microbiota on the outcomes of cutaneous leishmaniasis.

8 Feb 2023

Detection of wild poliovirus type 3 in the Netherlands

Researchers detect wild poliovirus type 3 during the environmental surveillance of poliovirus essential facilities in the Netherlands.

8 Feb 2023

Macrophages suppress Escherichia coli LF82 Gally prophage lytic cycle

Researchers analyze prophages of the LF82 strain of adherent-invasive Escherichia coli to better understand their behavior in vitro and within macrophages.

8 Feb 2023

COVID-19 vaccination increases saliva antibody levels after asymptomatic infection

Researchers correlate SARS-CoV-2 load and neutralizing capacity of all saliva immunoglobulins isotypes in asymptomatic individuals.

8 Feb 2023

Recent findings on T-cell immunity induced by SARS-CoV-2 infection and vaccination in immunocompromised individuals

Researchers discussed studies that explored T-cell immunity induced by SARS-CoV-2 infection and COVID-19 vaccination in cancer patients, individuals with HIV, and recipients of solid organ transplants.

8 Feb 2023

Study shows activation of pulmonary macrophages by SARS-CoV-2 spike glycoprotein

In a recent study published in the International Journal of Molecular Sciences, researchers investigated the effects of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) glycoprotein on human lung macrophage (HLM) activation and angiotensin-converting enzyme 2 (ACE2) and transmembrane serine protease 2 (TMPRSS2) expression in human lung macrophages.

7 Feb 2023

Bivalent boosters provide additional protection from BA.5, XBB, and XBB.1.5

In a recent Morbidity and Mortality Weekly Report (MMWR) published on the United States Center for Disease Control and Prevention (US-CDC) website, researchers analyzed data from the Increasing Community Access to Testing (ICATT), a nationwide pharmacy program run in the US for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) testing.

7 Feb 2023

Mucoactive drugs block SARS-CoV-2 infection

Researchers evaluate the effects of mucociliary active molecules on SARS-CoV-2 infection in vitro.

7 Feb 2023

Study reports two cases of ocular MPox in HIV-infected patients

Researchers review the symptoms, diagnosis, and treatment of ocular Mpox syndrome in men living with HIV infection.

7 Feb 2023

Study characterizes mutations in neuraminidase of human-like H5N1 influenza viruses

A study published in PLOS PATHOGENS describes the prevalence and functions of mutations in neuraminidase enzyme of avian H5N1 influenza viruses that are preferentially selected in human H5N1 influenza viruses.

7 Feb 2023

Study highlights the emergence of S. cerevisiae as an opportunistic fungal pathogen in immunosuppressed patients presenting several severe comorbidities

Researchers from Brazil presented a fatal case of a patient developing Saccharomyces cerevisiae infection and succumbing to septic shock after contracting and recovering from a SARS-CoV-2 infection.

7 Feb 2023

A novel multiplexed assay to diagnose Mpox and other viruses

Researchers evaluate the performance of novel assay to identify Mpox viral infection.

6 Feb 2023

Detecting novel SARS-CoV-2 variants via rapid RT-PCR assays

A new study on the medRxiv* preprint server assessed whether a novel assay could detect VOCs without substantial reductions in sensitivity.

6 Feb 2023

Study suggests that both mother and infant can contribute to the human milk microbiome

Researchers examined associations between the bacterial composition of human milk and maternal and infant factors.

6 Feb 2023

Molnupiravir-related mutational signatures among COVID-19 patients

Researchers explore a mutational signature related to molnupiravir in SARS-CoV-2 sequencing datasets.

3 Feb 2023

What is the effect of sex on the clinical characteristics and prognosis of COVID-19 patients?

Researchers evaluated COVID-19 management based on sex differences.

3 Feb 2023

Pfizer COVID-19 vaccine protects against reinfection in long-term care facility staff

Researchers examines the effectiveness of the Pfizer-BioNTech COVID-19 vaccine among long-term care facility staff members.

2 Feb 2023

Multispecies cluster of SARS-CoV-2 infections associated with an infected African lion

A recent paper described, for the first time, the transmission of this virus from an animal in a zoo to zoo employees.

2 Feb 2023

Establishment of a rapid and accurate SARS-CoV-2 antigen detection kit able to identify Omicron mutants

Researchers developed an antigen detection kit to identify the SARS-CoV-2 Omicron variant of concern.

2 Feb 2023

Researchers report a heterologous vaccination strategy against IBV in Chickens

Researchers reported on the immunogenicity of a heterologous vaccine regimen against IBV, comprising prime doses of QAC-encapsulated plasmid and a booster dose of MVA.

2 Feb 2023

Polymerase News and Research

A microbiota-driven mechanism underlies severity of leishmaniasis infection

Detection of wild poliovirus type 3 in the Netherlands

Macrophages suppress Escherichia coli LF82 Gally prophage lytic cycle

COVID-19 vaccination increases saliva antibody levels after asymptomatic infection

Recent findings on T-cell immunity induced by SARS-CoV-2 infection and vaccination in immunocompromised individuals

Study shows activation of pulmonary macrophages by SARS-CoV-2 spike glycoprotein

Bivalent boosters provide additional protection from BA.5, XBB, and XBB.1.5

Mucoactive drugs block SARS-CoV-2 infection

Study reports two cases of ocular MPox in HIV-infected patients

Study characterizes mutations in neuraminidase of human-like H5N1 influenza viruses

Study highlights the emergence of S. cerevisiae as an opportunistic fungal pathogen in immunosuppressed patients presenting several severe comorbidities

A novel multiplexed assay to diagnose Mpox and other viruses

Detecting novel SARS-CoV-2 variants via rapid RT-PCR assays

Study suggests that both mother and infant can contribute to the human milk microbiome

Molnupiravir-related mutational signatures among COVID-19 patients

What is the effect of sex on the clinical characteristics and prognosis of COVID-19 patients?

Pfizer COVID-19 vaccine protects against reinfection in long-term care facility staff

Multispecies cluster of SARS-CoV-2 infections associated with an infected African lion

Establishment of a rapid and accurate SARS-CoV-2 antigen detection kit able to identify Omicron mutants

Researchers report a heterologous vaccination strategy against IBV in Chickens

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