Polymerase News and Research

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What is the effect of sex on the clinical characteristics and prognosis of COVID-19 patients?

Researchers evaluated COVID-19 management based on sex differences.

3 Feb 2023

Pfizer COVID-19 vaccine protects against reinfection in long-term care facility staff

Researchers examines the effectiveness of the Pfizer-BioNTech COVID-19 vaccine among long-term care facility staff members.

2 Feb 2023

Multispecies cluster of SARS-CoV-2 infections associated with an infected African lion

A recent paper described, for the first time, the transmission of this virus from an animal in a zoo to zoo employees.

2 Feb 2023

Establishment of a rapid and accurate SARS-CoV-2 antigen detection kit able to identify Omicron mutants

Researchers developed an antigen detection kit to identify the SARS-CoV-2 Omicron variant of concern.

2 Feb 2023

Researchers report a heterologous vaccination strategy against IBV in Chickens

Researchers reported on the immunogenicity of a heterologous vaccine regimen against IBV, comprising prime doses of QAC-encapsulated plasmid and a booster dose of MVA.

2 Feb 2023

The trajectory of long-COVID in the general population of Scotland

Researchers presented the findings of the Long-COVID in Scotland Study (Long-CISS) conducted nationwide among the general population of Scotland.

2 Feb 2023

Risk factors for Omicron reinfections among previously infected frontline workers in the United States

Researchers examined a prospective cohort of frontline workers in the United States (US) previously infected with SARS-CoV-2. They attempted to identify risk factors that made this highly vulnerable population prone to reinfection by SARS-CoV-2 new variant of concern (VOC), Omicron, known for its high immune evading potential.

1 Feb 2023

Effectiveness of exome and genome sequencing to detect undiagnosed syndromes

Scientists review existing literature to evaluate the advancements in genomic and exome sequencing for the accurate detection of undiagnosed syndromes.

1 Feb 2023

Transcriptomics analysis identifies thousands of viroid-like circular RNA molecules

Metatranscriptomics analysis reveals the existence of over ten thousand viroids and viroid-like RNAs.

1 Feb 2023

Adding veliparib to chemotherapy can extend progression-free survival in patients with “BRCA-like” breast cancer

Results from the SWOG S1416 clinical trial show that adding veliparib to chemotherapy can significantly extend progression-free survival (PFS) times in patients with triple-negative breast cancer (TNBC) that has a "BRCA-like" phenotype.

31 Jan 2023

COVID-19 might increase risk of autoimmune diseases

Researchers examined the associations between coronavirus disease 2019 (COVID-19) and incident autoimmune diseases.

31 Jan 2023

Study demonstrates intrahost MPXV variation within a single lesion

Researchers reported on the clinical and molecular characteristics of MPXV infections in Finland.

31 Jan 2023

Acute tubulointerstitial nephritis and uveitis in children post-COVID-19

A new study reported a novel form of post-acute coronavirus disease 2019 (COVID-19) syndrome in children.

31 Jan 2023

Researchers devise a novel potential IBD treatment strategy that eliminates pathogenic T cells and encourages the proliferation of regulatory T cells

Researchers investigated the CAMCI strategy as an immunotherapeutic option for inflammatory bowel disease.

31 Jan 2023

Study assesses the sensitivity, specificity of rapid antigen tests and PCR tests for Omicron variant of COVID-19

Testing plays a crucial role in humanity's strategy to mitigate the effects of widespread COVID-19 infection. However, given multiple options for testing and the emergence of the highly contagious Omicron variant, how do we choose which test to use?

30 Jan 2023

Repression of endothelial TLR3 is a potential mechanism of SARS-CoV-2 infection-associated lung vascular remodeling

Researchers investigated whether endothelial TLR3 insufficiency contributes to lung vascular remodeling induced by SARS-CoV-2.

30 Jan 2023

Study shows COVID-19 induces body fat and other metabolic changes

In a recent study published in the journal Cureus, researchers explored the relationship between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and levels of serum insulin, body fat distribution, and insulin resistance (IR) estimated by homeostasis model assessment (HOMA).

29 Jan 2023

Polymerase News and Research

What is the effect of sex on the clinical characteristics and prognosis of COVID-19 patients?

Pfizer COVID-19 vaccine protects against reinfection in long-term care facility staff

Multispecies cluster of SARS-CoV-2 infections associated with an infected African lion

Establishment of a rapid and accurate SARS-CoV-2 antigen detection kit able to identify Omicron mutants

Researchers report a heterologous vaccination strategy against IBV in Chickens

The trajectory of long-COVID in the general population of Scotland

Risk factors for Omicron reinfections among previously infected frontline workers in the United States

Effectiveness of exome and genome sequencing to detect undiagnosed syndromes

Transcriptomics analysis identifies thousands of viroid-like circular RNA molecules

Adding veliparib to chemotherapy can extend progression-free survival in patients with “BRCA-like” breast cancer

COVID-19 might increase risk of autoimmune diseases

Study demonstrates intrahost MPXV variation within a single lesion

Acute tubulointerstitial nephritis and uveitis in children post-COVID-19

Researchers devise a novel potential IBD treatment strategy that eliminates pathogenic T cells and encourages the proliferation of regulatory T cells

Study assesses the sensitivity, specificity of rapid antigen tests and PCR tests for Omicron variant of COVID-19

Repression of endothelial TLR3 is a potential mechanism of SARS-CoV-2 infection-associated lung vascular remodeling

Study shows COVID-19 induces body fat and other metabolic changes

Children's tonsils are major sites of prolonged SARS-CoV-2 infection

Antiviral activity of natural flavonoids against various coronaviruses

Prenatal MRI helps visualize SARS-CoV-2 infection-induced abnormalities in the placenta and fetuses

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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