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Study reveals a complexity to how the body "regulates the regulators" of the immune system

Checkpoint inhibitors have become important tools in the cancer-fighting arsenal. By blocking proteins that normally restrain the immune response, these drugs can help the immune system destroy cancer cells.

20 Apr 2022

Inhaled nanoparticles can cross a protective barrier that protects fetuses, finds study

Inhaled nanoparticles – human-made specks so minuscule they can't be seen in conventional microscopes, found in thousands of common products – can cross a natural, protective barrier that normally protects fetuses, according to Rutgers University scientists studying factors that produce low-birth-weight babies.

20 Apr 2022

New findings reveal the long-standing underrepresentation of women in cardiology leadership roles

In a trio of studies analyzing trends in cardiology research funding, clinical trials and leadership, Johns Hopkins Medicine researchers say some progress has been made in the gender gap that has long favored men, but inequalities persist and are likely linked to ongoing disparities in outcomes for women with heart disease.

20 Apr 2022

Mutated gene found in breast cancer recurrences may help tumors to become more aggressive

A mutated gene found in more than 20% to 30% of breast cancer recurrences may help tumors become more aggressive and promote metastasis, according to a pair of new studies that uncover mechanisms behind these processes and point to new therapy targets.

20 Apr 2022

Lifelong excess weight almost doubles the risk of developing womb cancer, shows study

New research shows that lifelong excess weight almost doubles a woman's risk of developing womb cancer, according to a Cancer Research UK-funded study published today in BMC Medicine.

19 Apr 2022

Scientists identify a way to reverse drug resistance by rewiring the inner workings of leukemia cells

Researchers from Barts Cancer Institute at Queen Mary University of London have identified a way to reverse resistance to a group of cancer drugs, known as kinase inhibitors, in leukemia cells.

19 Apr 2022

Scientists create a bioengineered 3D model that mimics the biology of two rare neuromuscular diseases

A scientific team supported by the National Institutes of Health has created a tiny, bioengineered 3-D model that mimics the biology of chronic inflammatory demyelinating polyneuropathy and multifocal motor neuropathy, a pair of rare, devastating neuromuscular diseases.

19 Apr 2022

Using customized 'mini-antibodies' to mitigate chronic inflammation

Researchers at the Universities of Bonn and Sao Paulo have succeeded in mitigating chronic inflammation in mice using customized "mini-antibodies."

19 Apr 2022

New therapeutic option for HPV-positive head and neck carcinoma discovered

The various manifestations of head and neck carcinomas rank sixth in frequency worldwide and are fatal for about half a million people every year. In a quarter of cases, head and neck squamous cell carcinoma (HNSCC) is caused by human papillomavirus (HPV) and, currently, is not always treatable.

19 Apr 2022

Why cheap, older drugs that might treat covid never get out of the lab

In March 2020, Dr. Joseph Vinetz left the contemplative world of his Yale University infectious-disease laboratory and plunged into the covid ward at Yale New Haven Hospital, joining an army of health care workers who struggled to treat the deadly viral disease.

19 Apr 2022

New study pinpoints how immune checkpoint protein LAG3 modulates T cell activity

Fighting cancer and chronic disease is tiring work for the immune system. When T cells are engaged in this kind of lengthy battle, they can become exhausted, or unable to function properly.

18 Apr 2022

Study examines how race and sex influence tacrolimus pharmacokinetics in kidney transplant recipients

Kidney transplant survival is shorter, on average, in Black recipients compared to white recipients receiving similar treatment.

18 Apr 2022

Legalization of recreational marijuana lessens demand for costly prescription drugs

Legalization of recreational marijuana reduces demand for costly prescription drugs through state Medicaid programs, according to an analysis by a Cornell researcher and a collaborator.

18 Apr 2022

Researchers identify 16 distinct cell populations in a key brain region for substance use disorders

In a work of systematic biology that advances the field, University of Alabama at Birmingham researchers have identified 16 distinct cell populations in a complex area of the midbrain called the ventral tegmental area, or VTA.

18 Apr 2022

The involvement of the skeletal muscles in long COVID-19

Researchers reviewed the mechanisms of muscle tissue injury, aggravating conditions, and associated sequelae in long COVID‐19.

18 Apr 2022

Study identifies Etravirine and Dolutegravir as effective entry inhibitors of wild-type and predominant variants of SARS-CoV-2

Researchers identified drugs inhibiting the entry of SARS-CoV-2.

18 Apr 2022

Drugs News and Research

Study reveals a complexity to how the body "regulates the regulators" of the immune system

Inhaled nanoparticles can cross a protective barrier that protects fetuses, finds study

New findings reveal the long-standing underrepresentation of women in cardiology leadership roles

Mutated gene found in breast cancer recurrences may help tumors to become more aggressive

Lifelong excess weight almost doubles the risk of developing womb cancer, shows study

Scientists identify a way to reverse drug resistance by rewiring the inner workings of leukemia cells

Scientists create a bioengineered 3D model that mimics the biology of two rare neuromuscular diseases

Using customized 'mini-antibodies' to mitigate chronic inflammation

New therapeutic option for HPV-positive head and neck carcinoma discovered

Why cheap, older drugs that might treat covid never get out of the lab

New study pinpoints how immune checkpoint protein LAG3 modulates T cell activity

Study examines how race and sex influence tacrolimus pharmacokinetics in kidney transplant recipients

Legalization of recreational marijuana lessens demand for costly prescription drugs

Researchers identify 16 distinct cell populations in a key brain region for substance use disorders

The involvement of the skeletal muscles in long COVID-19

Study identifies Etravirine and Dolutegravir as effective entry inhibitors of wild-type and predominant variants of SARS-CoV-2

Study predicts that different statins exhibit divergent effects on host response to SARS-CoV-2 infection

Manipulating a specific gene from yeast could lead a new approach to combatting drug resistance

New insight into lymphoid cell maturity could pave the way for more effective IBD treatments

New chemical reaction creates a faster, simpler way of making tertiary amines for medicines

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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