Nephrology News and Research

RSS

Nephrology is a branch of internal medicine and pediatrics dealing with the study of the function and diseases of the kidney.

Scientists create synthetic Heparin in more varieties

Scientists at the University of North Carolina at Chapel Hill have learned to customize a key human enzyme responsible for producing heparin, opening the door to a more effective synthetic anticoagulant as well as treatments for other conditions.

25 Nov 2008

Study examines medical cost increases for individuals living with diabetes

People diagnosed with diabetes spend over $4,100 more each year on medical costs than people who don't have diabetes, a gap that increases substantially each year following the initial diagnosis, according to a study published online today in the journal Diabetes Care.

25 Nov 2008

Follow up results from first case of pulmonary hypertension treated with stem cells

Dr. Leonel Fernandez Liriano, Professor of Medicine at Pontifical Catholic University School of Medicine (PCUSM), announced nine month follow up results for the first patient treated with engineered stem cells in a clinical study of primary pulmonary hypertension.

25 Nov 2008

Declines in cancer incidence and death rates across U.S.

A new report from the nation's leading cancer organizations shows that, for the first time since the report was first issued in 1998, both incidence and death rates for all cancers combined are decreasing for both men and women, driven largely by declines in some of the most common types of cancer.

25 Nov 2008

Potassium loss from blood pressure drugs increases diabetes risk by 50%

According to researchers in the U.S. the loss of potassium experienced from taking blood pressure drugs may explain higher risk of adult diabetes.

25 Nov 2008

Pancreatic duct cells identified as new source of insulin-producing cells

Researchers at the Joslin Diabetes Center have shown that insulin-producing pancreatic beta cells can form after birth or after injury from progenitor cells within the pancreas that were not beta cells, a finding that contradicts a widely-cited earlier study that had concluded this is not possible.

24 Nov 2008

Potassium loss caused by diuretics may explain higher risk of adult diabetes

Johns Hopkins researchers have discovered that a drop in blood potassium levels caused by diuretics commonly prescribed for high blood pressure could be the reason why people on those drugs are at risk for developing type 2 diabetes.

24 Nov 2008

Humoral immunity in kidney transplantation

There are more than 76,000 end-stage renal disease patients waiting for one of the 17,000 kidneys transplanted each year, making a host rejection an unacceptable waste.

24 Nov 2008

Understanding lipid storage

Magazine articles describing ways to burn fat, lose weight, etc. are omnipresent in Western culture, but science's understanding of the way fat is stored in the cells of the human body is rather slimmer.

24 Nov 2008

World's first pediatric robotic bladder reconstruction performed

A 10-year-old Chicago girl born with an abnormally small bladder that made her incontinent has become the first patient to benefit from a new robotic-assisted bladder-reconstruction method developed by surgeons at the University of Chicago Medical Center.

20 Nov 2008

Helping diabetics through the holiday season

November ushers in American Diabetes Month - not only a time to be thankful for bustling basic and clinical research underway on the disease, but also the unofficial start of the holiday season.

20 Nov 2008

Ortho Biotech submits NDA for Trabectedin in relapsed ovarian cancer

Ortho Biotech Products, L.P. has announced the submission of a new drug application (NDA) to the U.S. Food and Drug Administration (FDA) for trabectedin when administered in combination with DOXIL (doxorubicin HCI liposome injection) for the treatment of women with relapsed ovarian cancer (ROC).

20 Nov 2008

Scientists trick immune system of mice into believing transplanted islets are its own cells

The body's immune system hates strangers. When its security patrol spots a foreign cell, it annihilates it.

20 Nov 2008

Low birth weight a risk factor for focal segmental glomerulosclerosis

Individuals who were underweight at birth are at increased risk of developing a condition called secondary focal segmental glomerulosclerosis, according to a study appearing in the January 2009 issue of the Clinical Journal of the American Society Nephrology ( CJASN ).

19 Nov 2008

Phosphaplatins kill ovarian, testicular, head and neck cancer cells

A new class of compounds called phosphaplatins can effectively kill ovarian, testicular, head and neck cancer cells with potentially less toxicity than conventional drugs, according to a new study published this week in the journal Proceedings of the National Academy of Sciences.

19 Nov 2008

Acute kidney injury predisposes elderly to serious kidney disease

Acute kidney injury (AKI) - which is often caused by trauma, illness, or surgery - predisposes elderly individuals to the most serious form of chronic kidney disease (CKD), known as end stage renal disease (ESRD), according to a study appearing in the January 2009 issue of the Journal of the American Society Nephrology (JASN).

19 Nov 2008

Diabetes cost U.S. estimated $217.5 billion in 2007

According to findings from a National Diabetes Economic Barometer study, undiagnosed, pre-diabetes and diabetes cost the United States an estimated $217.5 billion in 2007 due to higher medical expenditures and lost productivity.

18 Nov 2008

Researchers find deadly protein that acts as a cancer master switch

Two critical properties of cancer cells are their ability to divide without restraint and to spread away from the primary tumor to establish new tumor sites.

17 Nov 2008

Scientists identify dangerous 'two-faced' protein crucial to breast cancer spread and growth

Two critical properties of cancer cells are their ability to divide without restraint and to spread away from the primary tumor to establish new tumor sites.

17 Nov 2008

Hypertension may develop undetected in young African-American men

Young and healthy African-American men have higher central blood pressure and their blood vessels are stiffer compared to their white counterparts, signs that the African American men are developing hypertension early and with little outward sign, according to a new study.

17 Nov 2008