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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Folic acid supplementation mitigates risk of neural tube defects linked to HIV drug

Dolutegravir is a preferred medication for treating HIV infection, but it recently has been linked to a 6- to 9-fold increase in the risk for neural tube defects among babies born to mothers receiving the drug during early gestation.

24 Jul 2019

Unexpected discovery could improve treatment of cancer, other diseases

EU-funded researchers have discovered an important new mechanism by which cells flag and repair damage to their DNA - an unexpected finding that could improve the treatment of diseases such as cancer.

23 Jul 2019

Molecular action that enables cilantro to effectively delay certain seizures uncovered

Herbs, including cilantro, have a long history of use as folk medicine anticonvulsants. Until now, many of the underlying mechanisms of how the herbs worked remained unknown.

23 Jul 2019

Scientists identify new way to target bottleneck for cancer cell growth

The enzyme ribonucleotide reductase is a bottleneck for cancer cell growth. Scientists at Winship Cancer Institute of Emory University have identified a way of targeting ribonucleotide reductase that may avoid the toxicity of previous approaches, informing focused drug discovery efforts.

23 Jul 2019

UV-DDB protein scouts DNA damage and oversees repair

In the time it takes you to read this sentence, every cell in your body suffers some form of DNA damage. Without vigilant repair, cancer would run rampant, and now scientists at the University of Pittsburgh have gotten a glimpse of how one protein in particular keeps DNA damage in check.

22 Jul 2019

New chip device offers superior detection of blood residues for forensic applications

Ben-Gurion University of the Negev researchers have developed a new chip device that offers superior identification of miniscule blood residues for forensic applications.

22 Jul 2019

BIA Separations selected to support AveXis’ gene therapy pipeline

BIA Separations, a leading biochromatography development and manufacturing company, today announced it is collaborating with AveXis, a Novartis company, to enhance the commercial purification process for its gene therapy pipeline, beginning with Zolgensma (onasemnogene abeparvovec-xioi), the first U.S. Food and Drug Administration-approved gene therapy indicated for the treatment of pediatric patients with spinal muscular atrophy (SMA) who are less than two years of age.

22 Jul 2019

Study provides 'strongest evidence' yet for autism being a genetic condition

A new study has found that approximately 80 percent of a person’s risk of developing autism stems from inherited genetic factors.

22 Jul 2019

Scientists confirm HIV theory by sequencing 53-year old tissue

Researchers have extracted a near-complete HIV-1 genome from the lymph node tissue of a man who has been embedded in wax since 1966.

22 Jul 2019

Study provides new insight into how changes in DNA methylation contribute to diseases

More than half of our genome consists of transposons, DNA sequences that are reminiscent of ancient, extinct viruses.

19 Jul 2019

NIH researchers report largest genomic study of type 2 diabetes in sub-Saharan Africans

National Institute of Health researchers have reported the largest genomic study of type 2 diabetes in sub-Saharan Africans, with data from more than 5,000 individuals from Nigeria, Ghana and Kenya.

19 Jul 2019

IDT partners with Washington University to increase access to new NGS technologies

As part of its commitment to advocate for the genomics age, Integrated DNA Technologies aims to lower the barriers to access the latest NGS technologies.

From Integrated DNA Technologies 19 Jul 2019

Key metabolic changes found in patients with chemotherapy-related heart toxicity

More and more patients are being treated successfully for cancer. However, some cancer treatments that are very effective for breast cancer – medications like anthracyclines and trastuzumab – can cause heart dysfunction and lead to heart failure.

19 Jul 2019

Researchers identify brain somatic mutations linked to Alzheimer's disease

Researchers have identified somatic mutations in the brain that could contribute to the development of Alzheimer's disease. Their findings were published in the journal Nature Communications last week.

18 Jul 2019

Researchers develop a more precise version of CRISPR-Cas9 gene-editing system

A gene defect in humans causes progressive hearing loss in humans, resulting in deafness by their mid-20s. The same genetic mutation causes deafness in the Beethoven-mouse model.

18 Jul 2019

Research team detects novel mechanism of inheritance

Non-Mendelian, oligogenic inheritance could bean unrecognized and important element for occurrence ofhereditary retinal degenerations (HRDs, comprising retinitis pigmentosa) which are caused by ultra-rare mutations and cause progressive blindness.

18 Jul 2019

Scientists discover how resistance to the chemotherapy drug 5-fluorouracil arises

Australian researchers have unlocked the mystery as to why the chemotherapy drug 5-Fluorouracil is not effective at treating certain cancers.

17 Jul 2019

Molecular switches may control lifespan and healthspan separately, genetic discovery suggests

Aging research indicates that better healthspan--the quality of life as we age--may be more important than lifespan.

17 Jul 2019

Slug serves as 'command central' for determining breast stem cell health

A new study published in Cell Reports found that a transcription factor called Slug serves as 'command central' for determining breast stem cell health, regulating both stem cell activity and repair of DNA damage.

17 Jul 2019

Four young scientists receives Damon Runyon-Sohn Pediatric Cancer Fellowship Award

The Damon Runyon Cancer Research Foundation has named four outstanding young scientists as recipients of the prestigious Damon Runyon-Sohn Pediatric Cancer Fellowship Award, committing nearly $1 million to help address a critical shortage of funding for pediatric cancer research.

17 Jul 2019

DNA News and Research

Further Reading

Folic acid supplementation mitigates risk of neural tube defects linked to HIV drug

Unexpected discovery could improve treatment of cancer, other diseases

Molecular action that enables cilantro to effectively delay certain seizures uncovered

Scientists identify new way to target bottleneck for cancer cell growth

UV-DDB protein scouts DNA damage and oversees repair

New chip device offers superior detection of blood residues for forensic applications

BIA Separations selected to support AveXis’ gene therapy pipeline

Study provides 'strongest evidence' yet for autism being a genetic condition

Scientists confirm HIV theory by sequencing 53-year old tissue

Study provides new insight into how changes in DNA methylation contribute to diseases

NIH researchers report largest genomic study of type 2 diabetes in sub-Saharan Africans

IDT partners with Washington University to increase access to new NGS technologies

Key metabolic changes found in patients with chemotherapy-related heart toxicity

Researchers identify brain somatic mutations linked to Alzheimer's disease

Researchers develop a more precise version of CRISPR-Cas9 gene-editing system

Research team detects novel mechanism of inheritance

Scientists discover how resistance to the chemotherapy drug 5-fluorouracil arises

Molecular switches may control lifespan and healthspan separately, genetic discovery suggests

Slug serves as 'command central' for determining breast stem cell health

Four young scientists receives Damon Runyon-Sohn Pediatric Cancer Fellowship Award

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