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SARS-CoV-2 infection less severe in children and youth during first part of the pandemic

New research has found that children and youth may be at low risk of severe acute COVID-19, according to a study conducted during the first half of the pandemic and published in CMAJ (Canadian Medical Association Journal) https://www.cmaj.ca/lookup/doi/10.1503/cmaj.210053.

27 Sep 2021

mRNA COVID vaccines prove effective in the elderly

Coronavirus disease 2019 (COVID-19) proved extremely difficult to control once it entered a country – while there were a few success stories such as New Zealand, most countries ended up resorting to lengthy and economically painful lockdowns, among other restriction measures.

27 Sep 2021

New WHO Global Air Quality Guidelines recommend new air quality levels to protect human health

New WHO Global Air Quality Guidelines (AQGs) provide clear evidence of the damage air pollution inflicts on human health, at even lower concentrations than previously understood.

27 Sep 2021

Study shows prior COVID-19 and vaccination protects elderly against variants

In order to qualify the risk posed to the elderly, researchers from MUSE University in France began to investigate data from nursing homes that had faced outbreaks from variants of concern. Their work can be found on the medRxiv* preprint server while awaiting peer review.

27 Sep 2021

COVID-19 vaccine effectiveness barely affected by Delta variant, research suggests

Has the Delta (B.1.617.2) variant reduced vaccine effectiveness? If you ask Ian Foster of Argonne National Laboratory and colleagues, the answer is not really. New research published in the preprint medRxiv* server suggests vaccines approved in the United States are stable and well-performing.

27 Sep 2021

Study reveals surfaces of SARS-CoV-2 spike most resistant to antibody escape

A team of international scientists has formed a consortium to map the epitope landscape of a range of therapeutic monoclonal antibodies on the spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Moreover, the scientists characterized the neutralization potency of these antibodies and have investigated how emerging viral variants with spike mutations can impact antibody-mediated neutralization. They have recently published the consortium findings in the journal Science.

27 Sep 2021

A review of drugs harmful in COVID-19

In a new study, researchers investigate a number of drugs that are believed to potentially worsen outcomes in patients with COVID-19.

26 Sep 2021

Study shows SARS-CoV-2 breakthrough infections 18-fold lower than rate of infections among unvaccinated

In a recent study, researchers conducted a pilot study to assess the prevalence and features of VBTs through the use of sequencing and case data.

26 Sep 2021

Study to determine the characteristics and outcome of patients hospitalized with COVID-19

The study summarized the clinical presentation and demographic features of patients who were hospitalized with COVID-19.

26 Sep 2021

Factors predicting vaccine hesitancy in India

A recent study discusses vaccine hesitancy in India, which is one of the most populous countries in the world.

26 Sep 2021

Vaccine hesitancy and vaccination passports – a Japanese study

A new study from Keio University, Japan, provides an evaluation of the effectiveness of relaxing public interactions following vaccination against COVID-19.

26 Sep 2021

Childhood asthma is not a risk factor for COVID-19

A new study provides new insights on the association of childhood asthma and COVID-19.

26 Sep 2021

Novel antibody candidate shows potent binding to diverse SARS-CoV-2 variant mutations

Twist Bioscience Corporation (Nasdaq: TWST) today reported that its internally-discovered antibody candidate TB202-3 (CoVIC-094), demonstrated potent binding to diverse SARS-CoV-2 variant mutations, including strains with the E484K, N501Y, D614G, Y453F and K417N mutations in pseudovirus assays, indicating this therapeutic antibody may be effective in treating many strains of COVID-19.

25 Sep 2021

Further evidence of safety and efficacy of mRNA-1273 vaccine in preventing symptomatic COVID-19 and SARS-CoV-2 infection

A recent study supports the efficacy of the mRNA-1273 vaccine in preventing COVID-19 illness and disease severity.

24 Sep 2021

Inactivated egg-based Newcastle disease virus vaccine expressing SARS-CoV-2 spike protein

A new study presents initial results from a randomized, placebo-controlled phase 1/2 trial in Thailand.

24 Sep 2021

COVID-19 vaccination status among US college students

A new study has been published to study the correlations of COVID-19 vaccination status among college students.

24 Sep 2021

Presumed immunity in US remains below the threshold sufficient to disrupt SARS-CoV-2 transmission

Researchers have investigated publicly available data published to investigate the proportion of the US population that has become immune to SARS-CoV-2.

24 Sep 2021

No excess mortality during the Delta variant era in US state with high vaccination rates

Researchers have investigated the number of excess deaths during the initial spread of the Delta variant.

24 Sep 2021

A daily pill to treat covid could be just months away, scientists say

Within a day of testing positive for covid-19 in June, Miranda Kelly was sick enough to be scared. At 44, with diabetes and high blood pressure, Kelly, a certified nursing assistant, was having trouble breathing, symptoms serious enough to send her to the emergency room.

24 Sep 2021

Human milk antibodies elicited by vaccination show reduced activity against SARS-CoV-2 VoCs

In a study recently published on the medRxiv* preprint server, scientists from Singapore have assessed the levels of IgA-specific anti-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies in the breast milk of women recently immunized with the second dose of an mRNA-based coronavirus disease 2019 (COVID-19) vaccine.

24 Sep 2021

Respiratory News and Research

SARS-CoV-2 infection less severe in children and youth during first part of the pandemic

mRNA COVID vaccines prove effective in the elderly

New WHO Global Air Quality Guidelines recommend new air quality levels to protect human health

Study shows prior COVID-19 and vaccination protects elderly against variants

COVID-19 vaccine effectiveness barely affected by Delta variant, research suggests

Study reveals surfaces of SARS-CoV-2 spike most resistant to antibody escape

A review of drugs harmful in COVID-19

Study shows SARS-CoV-2 breakthrough infections 18-fold lower than rate of infections among unvaccinated

Study to determine the characteristics and outcome of patients hospitalized with COVID-19

Factors predicting vaccine hesitancy in India

Vaccine hesitancy and vaccination passports – a Japanese study

Childhood asthma is not a risk factor for COVID-19

Novel antibody candidate shows potent binding to diverse SARS-CoV-2 variant mutations

Further evidence of safety and efficacy of mRNA-1273 vaccine in preventing symptomatic COVID-19 and SARS-CoV-2 infection

Inactivated egg-based Newcastle disease virus vaccine expressing SARS-CoV-2 spike protein

COVID-19 vaccination status among US college students

Presumed immunity in US remains below the threshold sufficient to disrupt SARS-CoV-2 transmission

No excess mortality during the Delta variant era in US state with high vaccination rates

A daily pill to treat covid could be just months away, scientists say

Human milk antibodies elicited by vaccination show reduced activity against SARS-CoV-2 VoCs

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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