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UC Santa Cruz teams up to launch a web portal for people at risk of heritable stomach cancers

Coinciding with Stomach Cancer Awareness Month in November, the UC Santa Cruz Genomics Institute is teaming up with the patient advocacy nonprofit No Stomach For Cancer to release a web portal designed to help researchers identify individuals at risk of heritable stomach cancers.

24 Nov 2020

Researchers use single-cell RNA sequence analysis to address the cornea's healing process

The insulation around nerve cell components in our corneas have unique properties, and little is known about them.

24 Nov 2020

SARS-CoV-2 RNA best preserved in wastewater under freezing conditions

Wastewater surveillance has been reported to be a feasible and efficient way to monitor the prevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the current COVID-19 pandemic. A recent study draws attention to the need to freeze wastewater samples if the analysis is carried out later rather than immediately.

24 Nov 2020

COVID-19: HLA class I genotypes and mortality

The study, published on the preprint server medRxiv, explores the ability of HLA class I molecules to mediate the outcome in COVID-19 patients.

24 Nov 2020

Inherited DNA defects cause squamous cell carcinoma in kids with Fanconi anemia

Physicians and scientists at Cincinnati Children's Hospital Medical Center used new stem cell technology to regenerate and study living patient-specific skin in the lab.

24 Nov 2020

Study shows BICRA gene functions in neural development in humans, flies

Physicians and scientists are constantly on the lookout for new disease genes that can help them understand why patients have undiagnosed medical problems.

23 Nov 2020

Unique training program is bolstering Canada’s capacity to manufacture novel biotherapeutics

As COVID-19 highlights the urgent need to increase vaccine manufacturing around the world, a unique training program is bolstering Canada's capacity to manufacture vaccines, as well as viral immunotherapies for cancer and other emerging biotherapeutics.

23 Nov 2020

New link found between Alzheimer's dementia and Dlgap2 gene

A gene known for helping facilitate communication between neurons in the nervous system has been discovered to be connected with Alzheimer's dementia and cognitive decline, according to a national research team led by The Jackson Laboratory and University of Maine.

23 Nov 2020

Antimicrobial found in soaps worsens fatty liver disease in mice

University of California San Diego School of Medicine researchers found evidence that triclosan -- an antimicrobial found in many soaps and other household items -- worsens fatty liver disease in mice fed a high-fat diet.

23 Nov 2020

Early, late stages of neurodegeneration are distinct, finds study

Rice University biochemists Michael Stern and James McNew have studied how neurodegeneration kills cells.

23 Nov 2020

Novel targeted therapy blocks metabolic pathways in cancer cells with specific genetic defects

Researchers at The University of Texas MD Anderson Cancer Center have developed a novel targeted therapy, called POMHEX, which blocks critical metabolic pathways in cancer cells with specific genetic defects.

23 Nov 2020

Researchers develop recombinant SARS-CoV-2 model to aid vaccine and antiviral research

Researchers have developed a fluorescent reporter gene-bearing recombinant form of SARS-CoV-2, which is capable of replication.

23 Nov 2020

Compounds in traditional Chinese medicine herbs may inhibit SARS-CoV-2 infection

Using computational methods, a team of researchers identified three compounds in traditional Chinese medicine that could be used against SARS-CoV-2.

23 Nov 2020

Signaling pathway promotes cancer growth by blocking pro-growth signals from second major cancer pathway

Sometimes, too much of a good thing can turn out to be bad. This is certainly the case for the excessive cell growth found in cancer. But when cancers try to grow too fast, this excessive speed can cause a type of cellular ageing that actually results in arrested growth.

23 Nov 2020

Researchers discover mechanism by which abnormal proteins unleash toxicity in neurodegenerative diseases

Thanks to modern medicine, humans tend to live much longer than before. Unfortunately, this also opens a wider window to develop chronic diseases with late onset, such as neurodegenerative diseases.

23 Nov 2020

New findings could pave the way for more effective, safer and cheaper gene therapy

In a promising advance for affordable, personalized medicine, researchers have used metal-organic frameworks to successfully deliver the genetic snipping tool CRISPR/Cas9 into human cancer cells.

20 Nov 2020

UVA researchers discover gene responsible for the metastasis of triple-negative breast cancer

University of Virginia Cancer Center researchers have identified a gene responsible for the spread of triple-negative breast cancer to other parts of the body - a process called metastasis - and developed a potential way to stop it.

20 Nov 2020

SARS-CoV-2 suppresses ACE2 activity in COVID-19 patients

A recent study conducted by a team of international scientists has revealed that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative pathogen of coronavirus disease 2019 (COVID-19), suppresses the expression and function of human angiotensin-converting enzyme 2 (ACE2) and induces the expression of interferon-stimulated genes at the initial phase of infection. The study is currently available on the bioRxiv* preprint server.

20 Nov 2020

Scientists exploit 'trojan horse' feature in SARS-CoV-2 virus to create antivirals against COVID-19

Scientific analysis of a protein enzyme found in COVID-19 could lead to the development of new drugs to treat the virus, research led by Oxford Brookes University scientists has found.

20 Nov 2020

Scientists develop a new vaccine approach for HIV

Unlike so many other deadly viruses, HIV still lacks a vaccine. The virus--which continues to infect millions around the world--has proven especially tricky to prevent with conventional antibodies, in part because it evolves so rapidly in the body.

20 Nov 2020

Genes News and Research

UC Santa Cruz teams up to launch a web portal for people at risk of heritable stomach cancers

Researchers use single-cell RNA sequence analysis to address the cornea's healing process

SARS-CoV-2 RNA best preserved in wastewater under freezing conditions

COVID-19: HLA class I genotypes and mortality

Inherited DNA defects cause squamous cell carcinoma in kids with Fanconi anemia

Study shows BICRA gene functions in neural development in humans, flies

Unique training program is bolstering Canada’s capacity to manufacture novel biotherapeutics

New link found between Alzheimer's dementia and Dlgap2 gene

Antimicrobial found in soaps worsens fatty liver disease in mice

Early, late stages of neurodegeneration are distinct, finds study

Novel targeted therapy blocks metabolic pathways in cancer cells with specific genetic defects

Researchers develop recombinant SARS-CoV-2 model to aid vaccine and antiviral research

Compounds in traditional Chinese medicine herbs may inhibit SARS-CoV-2 infection

Signaling pathway promotes cancer growth by blocking pro-growth signals from second major cancer pathway

Researchers discover mechanism by which abnormal proteins unleash toxicity in neurodegenerative diseases

New findings could pave the way for more effective, safer and cheaper gene therapy

UVA researchers discover gene responsible for the metastasis of triple-negative breast cancer

SARS-CoV-2 suppresses ACE2 activity in COVID-19 patients

Scientists exploit 'trojan horse' feature in SARS-CoV-2 virus to create antivirals against COVID-19

Scientists develop a new vaccine approach for HIV

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