Antidepressant News and Research

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Antidepressants are medicines that treat depression. Your doctor can prescribe them for you. They can improve your mood, sleep, appetite and concentration. It may take several weeks for them to help. There are several types of antidepressants. You and your doctor may have to try several before finding what works best for you.

Anti-depressants could slow onset of Alzheimer's disease

A University of Pennsylvania researcher has discovered that the common selective serotonin reuptake inhibitor (SSRI) citalopram arrested the growth of amyloid beta, a peptide in the brain that clusters in plaques that are thought to trigger the development of Alzheimer's disease (AD).

15 May 2014

Antidepressant stops growth of plaques in mouse model of Alzheimer's disease

A commonly prescribed antidepressant can reduce production of the main ingredient in Alzheimer's brain plaques, according to new research at Washington University School of Medicine in St. Louis and the University of Pennsylvania.

15 May 2014

Naurex's two lead antidepressant programs achieve major milestones

Naurex Inc., a privately held biopharmaceutical company leveraging its unique platform to develop novel drugs for diseases of the central nervous system (CNS), today announced that its two lead antidepressant programs achieved major milestones.

6 May 2014

Eye movement disorder increases as we age, study finds

Abnormal binocular vision, which involves the way eyes work together as a team, increases dramatically as we age, according to research from the University of Waterloo. The study also found a correlation between this condition, general health and antidepressant use.

2 May 2014

Researchers demonstrate possibility of using blood test to detect depression

Researchers at the MedUni Vienna have demonstrated the possibility of using a blood test to detect depression. While blood tests for mental illnesses have until recently been regarded as impossible, a recent study clearly indicates that, in principle, depression can in fact be diagnosed in this way and this could become reality in the not too distant future.

30 Apr 2014

Study: Depression affects more than one out of three critical care survivors

Depression affects more than one out of three survivors of critical illness, according to a Vanderbilt study released in The Lancet Respiratory Medicine, and the majority of patients experience their symptoms physically rather than mentally.

26 Apr 2014

Study points to new therapeutic strategy for treating depression

A new study points to a conceptually novel therapeutic strategy for treating depression. Instead of dampening neuron firing found with stress-induced depression, researchers demonstrated for the first time that further activating these neurons opens a new avenue to mimic and promote natural resilience.

21 Apr 2014

New antidepressants open promising perspective for management of treatment-resistant depression

Notwithstanding numerous advances in the pharmacological treatment of depression, approximately 70% of patients do not remit after first-line antidepressant treatment.

15 Apr 2014

Women on antidepressant medication are more successful at breastfeeding

University of Adelaide researchers have found that women on antidepressant medication are more successful at breastfeeding their babies if they keep taking the medication, compared with women who quit antidepressants because of concerns about their babies' health.

11 Apr 2014

Viewpoints: A 'misguided' debate; trying to figure out who's uninsured; the safety net for the middle class

Supporters of Obamacare are celebrating that the law is not an unmitigated disaster, just a mitigated one. As enrollment closed (for most) on March 31, the system passed 7 million exchange sign-ups.

9 Apr 2014

Intranasal ketamine spray confers rapid antidepressant effect in patients with depressive disorder

A research team from the Icahn School of Medicine at Mount Sinai published the first controlled evidence showing that an intranasal ketamine spray conferred an unusually rapid antidepressant effect -within 24 hours-and was well tolerated in patients with treatment-resistant major depressive disorder.

9 Apr 2014

Depression linked to poor self-management in patients with diabetes

Adult patients with diabetes who trust their medical provider and feel included in treatment decisions are significantly more likely to take and maintain a newly prescribed antidepressant medication, according to a new study in the Journal of General Internal Medicine.

9 Apr 2014

1/3 of ICU patients develop depression that typically manifests as physical symptoms

A third of intensive care patients develop depression that typically manifests as physical, or somatic, symptoms such as weakness, appetite change, and fatigue, rather than psychological symptoms, according to one of the largest studies to investigate the mental health and functional outcomes of survivors of critical care, published in The Lancet Respiratory Medicine.

7 Apr 2014

BDSI enrolls first patient in Clonidine Topical Gel Phase 3 trial for treatment of painful diabetic neuropathy

BioDelivery Sciences International, Inc. announced today the enrollment of the first patient in the RHAPSODY Study, a Phase 3 clinical trial of Clonidine Topical Gel for the treatment of painful diabetic neuropathy.

3 Apr 2014

Ketamine offers novel treatment for patients with severe depression

New data show ketamine (a drug widely used for anaesthesia and pain relief) has a rapid antidepressant effect in some patients with severe depression. The first UK study of ketamine intravenous infusions in people with treatment-resistant depression was conducted by the Oxford Health NHS Foundation Trust and the University of Oxford.

3 Apr 2014

Seroxat in combination with acupuncture produces significant effect in patients with unipolar depression

Acupuncture is more effective than oral antidepressants in improving depressive symptoms, and produces fewer side effects than tricyclic antidepressants.

28 Mar 2014

Antidepressant medications during pregnancy linked with increased rates of preterm birth

Antidepressant medications taken by pregnant women are associated with increased rates of preterm birth. This finding reinforces the notion that antidepressants should not be used by pregnant women in the absence of a clear need that cannot be met through alternative approaches, say researchers from Brigham and Women's Hospital, Vanderbilt University, MetroWest Medical Center, and Tufts Medical Center.

28 Mar 2014

Antidepressant News and Research

Further Reading

Anti-depressants could slow onset of Alzheimer's disease

Antidepressant stops growth of plaques in mouse model of Alzheimer's disease

Naurex's two lead antidepressant programs achieve major milestones

Eye movement disorder increases as we age, study finds

Researchers demonstrate possibility of using blood test to detect depression

Study: Depression affects more than one out of three critical care survivors

Study points to new therapeutic strategy for treating depression

New antidepressants open promising perspective for management of treatment-resistant depression

Women on antidepressant medication are more successful at breastfeeding

Viewpoints: A 'misguided' debate; trying to figure out who's uninsured; the safety net for the middle class

Intranasal ketamine spray confers rapid antidepressant effect in patients with depressive disorder

Depression linked to poor self-management in patients with diabetes

1/3 of ICU patients develop depression that typically manifests as physical symptoms

BDSI enrolls first patient in Clonidine Topical Gel Phase 3 trial for treatment of painful diabetic neuropathy

Ketamine offers novel treatment for patients with severe depression

Seroxat in combination with acupuncture produces significant effect in patients with unipolar depression

Antidepressant medications during pregnancy linked with increased rates of preterm birth

Research points strong reason to develop new class of antidepressant drug

Nasal spray holds promise as potential alternative therapeutic approach for depression

Ventilator patients have considerable risk of developing psychological problems

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