Heart Attack (Myocardial Infarction) News and Research

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A Heart Attack (Myocardial Infarction) occurs when blood flow to a section of heart muscle becomes blocked. If the flow of blood isn’t restored quickly, the section of heart muscle becomes damaged from lack of oxygen and begins to die.

Heart attack is a leading killer of both men and women in the United States. But fortunately, today there are excellent treatments for heart attack that can save lives and prevent disabilities. Treatment is most effective when started within 1 hour of the beginning of symptoms. Heart attacks occur most often as a result of a condition called coronary artery disease (CAD). In CAD, a fatty material called plaque (plak) builds up over many years on the inside walls of the coronary arteries (the arteries that supply blood and oxygen to your heart). Eventually, an area of plaque can rupture, causing a blood clot to form on the surface of the plaque. If the clot becomes large enough, it can mostly or completely block the flow of oxygen-rich blood to the part of the heart muscle fed by the artery.

Takeda responds to FDA recommendation on Actos

Following a joint meeting today of the U.S. Food and Drug Administration (FDA) Endocrinologic and Metabolic Drugs Advisory Committee and the Drug Safety and Risk Management Advisory Committee, Takeda Global Research & Development (TGRD) underscores its position that ACTOS(R) (pioglitazone HCl) offers a proven safety profile regarding the risk of cardiovascular disease.

30 Jul 2007

Avandia too risky says expert

One of the members of the advisory panel set up to discuss the future of the diabetes pill Avandia says it should be removed from the market because it is too risky and offers no advantage over other alternatives.

30 Jul 2007

Polypill cure-for-all could become a killer

Doctors in Britain are warning that offering all men over 50 and all women over 60 a pill to protect them against heart disease and stroke, will only serve to encourage an unhealthy lifestyle.

30 Jul 2007

Thiazolinediones increase risk of heart failure

A class of drugs commonly used to treat type 2 diabetes may double the risk of heart failure, according to a new analysis by researchers at Wake Forest University School of Medicine and colleagues.

27 Jul 2007

Air pollution has a role to play in atherosclerosis

Should we be watching our exposure to airborne pollution as well as our cholesterol levels?

26 Jul 2007

Metformin gets top grade for diabetes

A type 2 diabetes drug taken orally and in widespread use for more than a decade has been found to have distinct advantages over nine other, mostly newer medications used to control the chronic disease, according to a study by researchers at Johns Hopkins.

26 Jul 2007

PA catheterization uses decreases substantially in U.S.

Use of the pulmonary artery catheter decreased by 65 percent in the U.S. between 1993 and 2004, possibly due to growing evidence that this invasive procedure does not reduce the risk of death for hospitalized patients, according to a study in the July 25 issue of JAMA .

25 Jul 2007

When it comes to medical care - skin color matters

The study found there is a racial bias in patient treatment and doctors are more likely to give better health care to whites than African Americans.

22 Jul 2007

Schering-Plough announces licensing of Acadesine

Schering-Plough Corporation has announced the worldwide licensing of acadesine, an investigational, potentially first-in-class adenosine regulating agent (ARA), from PeriCor Therapeutics, Inc., a privately held, specialty biopharmaceutical company.

20 Jul 2007

Web site puts physicians and hospitals under microscope

As health consumers across the country demand better and more detailed information about their physicians and hospitals, Beth Israel Deaconess Medical Center (BIDMC) is stepping up to detail its own performance efforts ranging from the percentage of clinicians who clean their hands to the number of times physicians take the proper steps in treating heart attack patients.

19 Jul 2007

Wearable cardiac telemedicine system

A Bluetooth heart monitor could text your local hospital if you are about to have a heart attack, according to research published today in Inderscience's International Journal of Electronic Healthcare.

18 Jul 2007

Review of Rosiglitazone for type 2 diabetes mellitus

Little evidence supports using rosiglitazone (Avandia) to improve the quality or length of life among adults with diabetes, according to a systematic review of data by German researchers.

18 Jul 2007

Elevated nonfasting triglyceride levels associated with heart attack

Results from two studies indicate that elevated nonfasting triglyceride levels are associated with cardiovascular events such as a heart attack, with one study finding that triglyceride levels measured after fasting does not show this association, according to studies in the July 18 issue of JAMA .

18 Jul 2007

Heart patches that stimulate regeneration

When human hearts are injured, as during a heart attack, healthy tissue normally can't regrow.

18 Jul 2007

Special patch improves heart function after heart attacks

Researchers in the U.S. have developed a special patch which regenerates cardiac cells after a heart attack; when the patch is placed on the damaged area of the heart it improves heart function.

17 Jul 2007

Nasal insufflation for sufferers of sleep apnea

Researchers at Johns Hopkins University have found that symptoms in patients with obstructive sleep apnea and hypopnea can be significantly reduced through treatment with nasal insufflation (TNI), using a nasal cannula to deliver warm, humidified air at a high flow rate.

17 Jul 2007

Analysis of diabetes drugs

Most oral medications prescribed for type 2 diabetes are similarly effective for reducing blood glucose, but the drug metformin is less likely to cause weight gain and may be more likely than other treatments to decrease so-called bad cholesterol, according to a report funded by HHS Agency for Healthcare Research and Quality.

17 Jul 2007

Insulin resistance in skeletal muscle can be countered through exercise

Abdominal fat, the spare tire that many of us carry, has long been implicated as a primary suspect in causing the metabolic syndrome, a cluster of conditions that includes the most dangerous heart attack risk factors: prediabetes, diabetes, high blood pressure, and changes in cholesterol.

17 Jul 2007

Diabetics experience more complications during hospitalization for trauma

Individuals with diabetes appear to spend more days in the intensive care unit, use more ventilator support and have more complications during hospitalization for trauma than non-diabetics, according to a report in the July issue of Archives of Surgery.

17 Jul 2007

Women who have suffered heart attacks have higher rates of depression compared to men

Women who have suffered heart attacks have higher rates of lingering depressive symptoms compared to their male counterparts, a University of Alberta and McGill University study shows.

16 Jul 2007