Oncology News and Research

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Oncology, meaning bulk, mass, or tumor, and the suffix ''-logy'', meaning "study of") is a branch of medicine that deals with tumors (cancer). A medical professional who practices oncology is an ''oncologist''.

Global Virus Network accelerates mpox diagnostic research

With global attention shifting away from mpox after recent declines in case counts, the Global Virus Network (GVN) is warning against complacency and urges accelerating efforts to strengthen outbreak readiness.

25 Sep 2025

Patient-derived organoids advance cancer therapy and vaccines

Tiny, three-dimensional organoid models are reshaping cancer research by recreating the intricate architecture and diversity of human tumors.

25 Sep 2025

Leading cancer organizations call for action to boost HPV vaccine coverage

VCU Massey Comprehensive Cancer Center, along with 61 other National Cancer Institute (NCI)-Designated Cancer Centers, several leading national cancer health organizations and the University of Puerto Rico Comprehensive Cancer Center, have endorsed a joint statement urging the nation's health care systems, health care providers, parents, caregivers and the public to choose the human papillomavirus (HPV) vaccination for cancer prevention.

25 Sep 2025

Colorectal cancer first presents with unexplained strokes and blood clots

A new case report was published in Volume 12 of Oncoscience on September 15, 2025, titled "When strokes reveal a hidden malignancy: An atypical case of metastatic colorectal cancer with extensive thromboembolism."

25 Sep 2025

Loss of Trp53 gene affects immune responses in ovarian cancer

A new research paper was published in Volume 16 of Oncotarget on September 22, 2025, titled "Loss of Trp53 results in a hypoactive T cell phenotype accompanied by reduced pro-inflammatory signaling in a syngeneic orthotopic mouse model of ovarian high-grade serous carcinoma."

24 Sep 2025

Global cancer cases and deaths expected to soar by 2050 despite advances in treatment

There has been a rapid increase in the global number of cancer cases and deaths between 1990 and 2023, despite advances in cancer treatment and efforts to tackle cancer risk factors over that same time period.

24 Sep 2025

Research shows different EML4-ALK variants drive lung cancer aggressiveness

About five percent of lung adenocarcinomas, one of the most common forms of lung cancer, are driven by a faulty fusion of two genes, EML4 and ALK.

23 Sep 2025

Groundbreaking tool could transform acute leukemia diagnosis and treatment

Researchers at Dana-Farber Cancer Institute have developed a groundbreaking diagnostic tool that could transform the way acute leukemia is identified and treated.

22 Sep 2025

Regular mammograms linked to longer survival in women over 80

For many older women, the question of whether to continue breast cancer screening has been uncertain. While most guidelines recommend mammograms up to age 74, advice for women 75 and older has been less clear.

22 Sep 2025

Magnetically-powered nanorobots enhance drug uptake in tumors

Spiky nanorobots powered by magnets have been developed to carry drugs and pierce tumor cell membranes, a key barrier to effective cancer treatment. By boosting drug entry, these "microscopic scalpels" improved chemotherapy results in laboratory and animal studies, suppressing tumor growth and extending survival.

22 Sep 2025

COST Actions drive innovation in cancer research across Europe

Cancer is a major challenge in the modern world, affecting millions of people across Europe. The prevalence of this disease requires the development of innovative and complementary treatment approaches.

19 Sep 2025

Genomic testing speeds patient accrual in high-risk prostate cancer trial

The NRG Oncology NRG-GU009 (PREDICT-RT) study evaluating intensified and de-intensified concurrent radiation regimens based on the genomic risk of patients with high-risk prostate cancer completed accrual and met its accrual milestone of 2,478 patients approximately two years earlier than the trial's anticipated accrual completion date.

19 Sep 2025

Study identifies immune biomarkers for personalized therapies in pediatric germ cell tumors

A study conducted by the Molecular Oncology Research Center (CPOM) at Hospital de Amor in Barretos (formerly Barretos Cancer Hospital) in the state of São Paulo, Brazil, has identified possible biomarkers that could guide the development of more personalized therapies for pediatric germ cell tumors (GCTs).

18 Sep 2025

PANoptosis emerges as a promising strategy against liver cancer

Liver cancer, particularly hepatocellular carcinoma (HCC), remains one of the deadliest cancers, driven by high recurrence and resistance to therapy.

18 Sep 2025

Oral microbiome linked to threefold higher pancreatic cancer risk

Twenty-seven species of bacteria and fungi among the hundreds that live in people's mouths have been collectively tied to a 3.5 times greater risk of developing pancreatic cancer, a study led by NYU Langone Health and its Perlmutter Cancer Center shows.

18 Sep 2025

New molecule offers a more targeted and potent immunotherapy

A newly developed molecule brings together two powerful immunotherapy strategies in one treatment. Researchers at the University of Basel and University Hospital Basel, Switzerland, have demonstrated that this fusion protein can both block the "do not attack" signal used by cancer cells and selectively activate tumor-fighting immune cells. This dual action could pave the way for more effective cancer therapies with fewer side effects.

18 Sep 2025

Targeted radiation shows promise for rare solitary fibrous tumors

A novel targeted radiation approach for a rare form of malignant tumor-the solitary fibrous tumor (SFT)-has shown significant success, achieving a near-complete response in three patients.

17 Sep 2025

Study highlights critical mental health risk for eczema patients

A new international study presented today at the European Academy of Dermatology and Venereology (EADV) Congress 2025 reveals that adults with atopic eczema (AE) are significantly more likely to experience suicidal thoughts, with researchers uncovering the key factors driving this elevated risk.

17 Sep 2025

New findings show lymph nodes educate T cells to combat disease

A team of researchers, led by the Peter Doherty Institute for Infection and Immunity (Doherty Institute), explored the cellular and molecular interactions revealing how lymph nodes play a crucial role in the fight against chronic infection and cancer.

17 Sep 2025

Uterine corpus malignancies with pregnancy-like features lead to poor survival outcomes

A new review was published in Volume 12 of Oncoscience on September 4, 2025, titled "Prognostic significance of trophoblastic differentiation and β-hCG secretion in somatic malignancies of uterine corpus: A systematic review with survival analysis."

16 Sep 2025