Organoids News and Research

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Organoids are three-dimensional cell cultures from embryonic stem cells or induced pluripotent stem cells that model important features of whole organs.

Gut disease and gene analysis networks

Gut diseases are difficult to diagnose in many cases, and their underlying dysfunction is hard to understand in many cases. Now, a new study published in the journal Molecular Omics promises to uncover a better insight into how these conditions occur and their mechanisms, by providing a deeper look at how genes interact in complex ways in health and fail to do so in disease.

11 Dec 2019

Bruker launches Luxendo TruLive3D Imager light-sheet imaging system

At the 2019 joint meeting of the American Society for Cell Biology and European Molecular Biology Organization, Bruker today announced the launch of the Luxendo TruLive3D Imager light-sheet imaging system.

From Bruker Nano Surfaces and Metrology 11 Dec 2019

A network approach to explore the causes of IBD

Diseases of the gut are often notoriously difficult to diagnose, nevermind understand, which is where a network-based approach comes in.

10 Dec 2019

New technique holds promise in cancer research and science studies

A new technique reported this week in Science overcomes several limitations of typical high-throughput chemical screens conducted on cell samples. Such screens are commonly used to try to discover new cancer drugs, and in many other biomedical applications.

8 Dec 2019

FDA-approved drug repairs gut leakiness associated with ulcerative colitis

A research team led by biomedical scientists at the University of California, Riverside, has found that a drug approved by the FDA to treat rheumatoid arthritis and ulcerative colitis can repair permeability defects in the gut's epithelium.

4 Dec 2019

New human colon-on-a-chip enables in vitro study of mucus physiology

We have a mutualistic but complicated relationship with the collection of microbes in our gut known as the intestinal microbiome.

3 Dec 2019

LACV-infected cerebral organoids reveal how to protect neurons from virus-induced death

Scientists have determined that La Crosse virus, which can cause inflammation of the brain, or encephalitis, in children, affects brain cells differently depending on their developmental stage.

26 Nov 2019

Scientists grow complex organoids in the lab

Scientists at the University of Würzburg have successfully produced human tissues from stem cells. They have a complexity similar to that of normal tissue and are far superior to previous structures.

19 Nov 2019

The Achilles heel of APC-mutated colon tumors identified

In almost all cases of colon cancer, a specific gene is mutated – this offers opportunities to develop broadly effective therapeutic approaches. Research teams in Würzburg have taken this a step further.

5 Nov 2019

MSU research team wins NIH grant to explore new way to study the gut's immune system

One day, instead of requiring a painful needle injection, vaccinating against a host of formerly fatal diseases could be as simple as swallowing a pill. But getting to that point means first gaining a better understanding of how the immune system works in the complex human gut, according to Montana State University researcher Diane Bimczok.

30 Oct 2019

Study seeks participants with VCFS-related psychosis to help create biobank of cerebral organoids

A landmark study is calling for at least 50 people in the U.S. with Velo-Cardio-Facial Syndrome (VCFS)-related psychosis to provide blood samples to create the world’s largest VCFS biobank to date of tiny spheres of neural tissue called "cerebral organoids."

24 Oct 2019

New NPO formed to accelerate development of therapies for Shankopathies

Parents of children affected by Phelan-McDermid syndrome (PMS) announce the formation of CureSHANK, a nonprofit organization on a mission to accelerate drug development in PMS and other diseases related to the SHANK genes for which there are currently no FDA approved treatments.

23 Oct 2019

Binghamton biomedical professor receives $1.2 million in grants toward diabetes cure

A biomedical engineering professor at Binghamton University, State University of New York is trying to find a cure for diabetes from several different angles, and three federal grants totaling nearly $1.2 million will aid her and her research team in that quest.

21 Oct 2019

Highly sensitive method can 'track' fat metabolism

Without fat, nothing works in the body: These substances serve as energy suppliers and important building blocks - including for the envelopes of living cells.

14 Oct 2019

Scientists demonstrate potential method for treating advanced liver cancers

Liver cancer is the second leading cause of cancer-related deaths worldwide. The most common primary liver cancer in adults is known as hepatocellular carcinoma (HCC), and accounts for approximately 780,000 deaths every year.

9 Oct 2019

Scientists use organoid technology to achieve stable long-term cultures of mouse urothelial cells

Investigation of biological mechanisms in urothelial tissue -one of the three types of tissue that make up the urinary system- has always been very limited due to the lack of technologies that allow working with stable and long-term populations of the cells that compose it.

4 Oct 2019