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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Chemicals produced by gut microbiome could help identify children at risk of organ failure

Chemicals produced by healthy bacteria could be used to assess the health of the gut microbiome and help identify critically-ill children at greatest risk of organ failure, a study published in Critical Care Medicine has found.

14 Jun 2019

Researchers identify effective drug combinations for malignant brain tumor in mice

Usually, scientists study the molecular biology of cancer to find new treatments, but sometimes, it is the other way round: when trying to find new treatments, scientists find key information on cancer biology.

14 Jun 2019

Mount Sinai researchers win a contract from DARPA to develop technology that measures threat exposures

Researchers at the Icahn School of Medicine at Mount Sinai have been awarded a contract from the Defense Advanced Research Projects Agency, a research agency within the U.S. Department of Defense, to find molecular signatures in blood that identify previous exposures and time of exposure to materials that could be associated with weapons of mass destruction (including infectious agents, chemicals, and radiation).

13 Jun 2019

UK government to consider fortifying flour with folic acid to combat neural tube defects

A 12-week consultation has been launched to discuss whether folic acid should be added to flour in the UK.

13 Jun 2019

Engineers crack the code to quickly diagnose anti-malarial drug resistance

One of the keys to quickly diagnosing anti-malarial drug resistance -- potentially saving lives -- lies in testing whole blood instead of extracting DNA, eliminating processing steps that can take hours or days.

13 Jun 2019

IDT unveils latest additions to NGS portfolio at European Human Genetics Conference

As part of its ongoing mission to advocate for researchers in the genomics age, Integrated DNA Technologies will unveil the latest additions to its NGS catalog to the European market at the European Human Genetics Conference in Gothenburg, Sweden on 15–18 June, 2019.

From Integrated DNA Technologies 13 Jun 2019

New assay uses a drop of blood to detect patients' resistance to antimalarial drugs

Antimalarial drugs appear to follow a typical pattern, with early effectiveness eventually limited by the emergence of drug resistance.

13 Jun 2019

Norovirus structures could help develop therapeutics to fight food-borne illness

Noroviruses are a leading cause of food-borne illness outbreaks, accounting for 58% of all outbreaks and cause 685 million cases worldwide each year. There is no effective therapeutic against them. Having knowledge of the intricate structure of the outer layer of noroviruses, the capsid, which allows the virus to attach to its human host, could help in vaccine development.

13 Jun 2019

More screening and new treatments needed for sickle cell disease

The promise of new treatments for sickle cell disease, a group of inherited red blood cell disorders, has never been so great, but it will only be realized if there is constant investment in health policies such as programs for screening newborns, especially in sub-Saharan Africa, where most cases occur.

13 Jun 2019

New technology harnesses bacterial jumping genes for precise DNA integration

A new discovery by researchers at Columbia University Vagelos College of Physicians and Surgeons could fix one of the major shortcomings of current gene-editing tools, including CRISPR, and offer a powerful new approach for genetic engineering and gene therapy.

13 Jun 2019

Researchers reveal underlying mechanism that protects genetic transcripts in cells

The cell contains transcripts of the genetic material, which migrate from the cell nucleus to another part of the cell. This movement protects the genetic transcripts from the recruitment of "spliceosomes".

13 Jun 2019

Identifying colorectal cancer subtypes in patients could help provide better care

Colorectal cancer is the second leading cause of cancer death in the U.S., expected to cause about 51,000 deaths in 2019. But until now, it was unclear which drugs were most effective for which patients.

12 Jun 2019

Russian researcher announces plans to create more CRISPR-edited babies

A researcher has announced controversial plans to create gene-edited babies, dividing the scientific community.

12 Jun 2019

Identifying subtype of colorectal cancer may help oncologists determine most effective treatment

12 Jun 2019

Researchers identify new sarcoma familial risk gene

A team of WA researchers has uncovered new genes that could play an important role in the development of sarcoma, a group of rare bone, muscle and connective tissue cancers.

12 Jun 2019

Genetic variations linked with persistence of immunity after routine childhood vaccination

A genome-wide search in thousands of children in the UK and Netherlands has revealed genetic variants associated with differing levels of protective antibodies produced after routine childhood immunizations.

12 Jun 2019

Chemists build rich collection of natural product-like macrocycles for drug discovery

Natural products, or their close derivatives, make some of our most potent medicines, among which macrocycles with their large carbon-rich ring systems are one class.

12 Jun 2019

A 'one-two punch' approach to destroy cancerous ovarian cells

Researchers from the University of Montreal Hospital Research Centre have developed a two-step combination therapy to destroy cancer cells.

11 Jun 2019

Study emphasizes the need for personalized dietary plans, as not even twins show the same responses

Researchers have found that many widely accepted dietary guidelines are not suitable for everyone, with even twins responding differently to the same foods.

11 Jun 2019

Polygenic risk scores based on entire genome sequence may reliably predict heart disease

Specialized risk scores derived from testing that calculates the cumulative effect of an individual's entire DNA sequence, the genome, may reliably predict heart disease in people who have not yet had a heart attack, according to new research in Circulation: Genomic and Precision Medicine, an American Heart Association journal.

11 Jun 2019

DNA News and Research

Further Reading

Chemicals produced by gut microbiome could help identify children at risk of organ failure

Researchers identify effective drug combinations for malignant brain tumor in mice

Mount Sinai researchers win a contract from DARPA to develop technology that measures threat exposures

UK government to consider fortifying flour with folic acid to combat neural tube defects

Engineers crack the code to quickly diagnose anti-malarial drug resistance

IDT unveils latest additions to NGS portfolio at European Human Genetics Conference

New assay uses a drop of blood to detect patients' resistance to antimalarial drugs

Norovirus structures could help develop therapeutics to fight food-borne illness

More screening and new treatments needed for sickle cell disease

New technology harnesses bacterial jumping genes for precise DNA integration

Researchers reveal underlying mechanism that protects genetic transcripts in cells

Identifying colorectal cancer subtypes in patients could help provide better care

Russian researcher announces plans to create more CRISPR-edited babies

Identifying subtype of colorectal cancer may help oncologists determine most effective treatment

Researchers identify new sarcoma familial risk gene

Genetic variations linked with persistence of immunity after routine childhood vaccination

Chemists build rich collection of natural product-like macrocycles for drug discovery

A 'one-two punch' approach to destroy cancerous ovarian cells

Study emphasizes the need for personalized dietary plans, as not even twins show the same responses

Polygenic risk scores based on entire genome sequence may reliably predict heart disease

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