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Bayesian viral allele selection for SARS-CoV-2 genomic surveillance

In a recent study posted to the bioRxiv* preprint server, researchers assessed the selection effects in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) using Bayesian viral allele selection.

12 May 2022

Penn study finds low uptake of first mutation-targeted bladder cancer drug

The first bladder cancer drug targeting a cancer-driving gene mutation has been used relatively little despite its clear efficacy in a clinical trial, suggests a study from researchers at the Perelman School of Medicine at the University of Pennsylvania.

12 May 2022

Worldwide study of diverse populations sheds new light on how genes contribute to type 2 diabetes

Ongoing worldwide research of diverse populations by an international team of scientists, including a University of Massachusetts Amherst genetic epidemiologist, has shed important new light on how genes contribute to type 2 diabetes.

12 May 2022

Discovery of new structure in the egg cells of zebrafish could provide insights into human reproduction

It is humbling to realize that we humans share about 70% of our genes with zebrafish. There are also a whole host of other similarities that make these small transparent fish an ideal animal model for the study of many human diseases and biological processes.

12 May 2022

Repeated DNA sequences in the genome may contribute to schizophrenia risk

Researchers at The Hospital for Sick Children (SickKids) and Centre for Addiction and Mental Health (CAMH) have found that repeated DNA sequences in the genome may contribute to an individual's risk of developing schizophrenia.

12 May 2022

Analysis finds baffling variations in the treatment for heart attack patients in high-income nations

The best way to treat acute myocardial infarctions, commonly known as heart attacks, has been long established by international consensus. The types of treatments and recommended procedures are well-defined, widely known, and readily available in modern hospitals.

12 May 2022

Playing video games can help increase children’s intelligence

Researchers at Karolinska Institutet in Sweden have studied how the screen habits of US children correlates with how their cognitive abilities develop over time.

12 May 2022

Mitochondrial respiratory chain is essential for NLRP3 inflammasome activation

Northwestern Medicine investigators recently discovered that the mitochondrial respiratory chain — a series of protein complexes essential for a cellular respiration and energy production — is necessary for the activation of another protein complex linked to inflammation and the progression of chronic diseases, according to a study published in Nature Immunology.

12 May 2022

Phase 1 clinical trial of vaccine for rare but deadly mosquito-borne viruses shows promising results

A vaccine for eastern equine encephalitis virus (EEEV), western equine encephalitis virus (WEEV), and Venezuelan equine encephalitis virus (VEEV) was found to be safe, well-tolerated and induced a neutralizing antibody response in adult volunteers, according to newly published results from a Phase 1 clinical trial.

12 May 2022

Researchers pursue a new way to use milk for delivering cancer-fighters to the brain

In health care, perhaps no word sends a more chilling message than "cancer." Brain tumors, for example, prove especially resistant to current treatments. Only 5% of patients with that condition survive more than three years and the median survival time is 10 to 14 months.

12 May 2022

Researchers identify cellular serpins as host factors that restrict SARS-CoV-2 infection

Researchers investigated differences in susceptibility between individuals and may have discovered a new opportunity for treatment.

12 May 2022

Nerve gas sarin largely responsible for Gulf War illness, study shows

For three decades, scientists have debated the underlying cause of Gulf War illness (GWI), a collection of unexplained and chronic symptoms affecting veterans of the Persian Gulf War.

12 May 2022

Researchers Identify Potential Target for Rhabdomyosarcoma Recurrence Prevention

In this interview, News-Medical speaks to Anand Patel and Michael Dyer from St. Jude's Children's Research Hospital about their recent research suggesting EGFR inhibitors may prevent rhabdomyosarcoma recurrence.

12 May 2022

Research describes how DNA damage can affect neural health and function

A new research paper in the journal EMBO Reports describes how DNA damage can affect neural health and function.

12 May 2022

The promise of RNA medicine is targeted and personalized

The development of messenger RNA (mRNA) vaccines against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has only increased the impetus in this field.

11 May 2022

Brain circuit in the anterior thalamus is crucial for remembering how to navigate a maze

As people age, their working memory often declines, making it more difficult to perform everyday tasks. One key brain region linked to this type of memory is the anterior thalamus, which is primarily involved in spatial memory - memory of our surroundings and how to navigate them.

11 May 2022

Genetic News and Research

Bayesian viral allele selection for SARS-CoV-2 genomic surveillance

Penn study finds low uptake of first mutation-targeted bladder cancer drug

Worldwide study of diverse populations sheds new light on how genes contribute to type 2 diabetes

Discovery of new structure in the egg cells of zebrafish could provide insights into human reproduction

Repeated DNA sequences in the genome may contribute to schizophrenia risk

Analysis finds baffling variations in the treatment for heart attack patients in high-income nations

Playing video games can help increase children’s intelligence

Mitochondrial respiratory chain is essential for NLRP3 inflammasome activation

Phase 1 clinical trial of vaccine for rare but deadly mosquito-borne viruses shows promising results

Researchers pursue a new way to use milk for delivering cancer-fighters to the brain

Researchers identify cellular serpins as host factors that restrict SARS-CoV-2 infection

Nerve gas sarin largely responsible for Gulf War illness, study shows

Researchers Identify Potential Target for Rhabdomyosarcoma Recurrence Prevention

Research describes how DNA damage can affect neural health and function

The promise of RNA medicine is targeted and personalized

Brain circuit in the anterior thalamus is crucial for remembering how to navigate a maze

Discovery of host co-factors necessary for SARS-CoV2 infection

New research reveals a potent weapon against Parkinson's disease

Direct influenza infection of the heart drives cardiac complications, study reveals

New smoking-cessation program helps more cancer patients to quit successfully

eBook: Using iPSCs models for human disease research and drug discovery eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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