Antibiotic News and Research

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Antibiotics are drugs used to treat infections caused by bacteria and other microorganisms.

Gut microbial metabolite plays a role in exacerbating thrombosis

A gut microbial metabolite called 2-methylbutyrylcarnitine (2MBC) plays a role in exacerbating thrombosis -- the formation of blood clots – researchers report February 23rd in the journal Cell Metabolism.

23 Feb 2024

Research reveals bacteria's dynamic defense duo against phage viruses

Scientists at the University of Southampton have discovered that bacteria can pair up their defense systems to create a formidable force, greater than the sum of its parts, to fight off attack from phage viruses.

23 Feb 2024

Key link discovered between spread of antibiotic resistance genes and drug resistance evolution

Biomedical engineers at Duke University have uncovered a key link between the spread of antibiotic resistance genes and the evolution of resistance to new drugs in certain pathogens.

23 Feb 2024

Breakthrough discovery offers hope for reducing infections in cystic fibrosis patients

University of Queensland researchers have identified an opportunity to reduce infections in people living with cystic fibrosis.

22 Feb 2024

Maternal antibiotic use during childbirth tied to higher risk of autoimmune diseases in children

Children whose mothers have received antibiotic treatment during childbirth are more likely to develop autoimmune diseases compared to their counterparts, according to a recent registry-based study conducted at the University of Oulu, Finland, involving nearly 46,000 children.

22 Feb 2024

University College Dublin launches new Centre for One Health to solve global health challenges

University College Dublin (UCD) today launched its new Centre for One Health. The Centre is dedicated to advancing research, education and collaboration on the One Health approach to solving global health challenges which recognizes the interconnectedness of human, animal and planetary health.

22 Feb 2024

Digital DNA melting analysis can be a faster and more reliable tool for pathogen detection

A new analysis method can detect pathogens in blood samples faster and more accurately than blood cultures, which are the current state of the art for infection diagnosis.

21 Feb 2024

Mutation in E. coli bacteria linked to severe disease

Queensland researchers have discovered that a mutation allows some E. coli bacteria to cause severe disease in people while other bacteria are harmless, a finding that could help to combat antibiotic resistance.

21 Feb 2024

AGA guideline endorses fecal microbiota transplant as treatment for recurrent C. diff infection

In the first comprehensive evidence-based guideline on the use of fecal microbiota-based therapies for gastrointestinal disease, the American Gastroenterological Association recommends fecal microbiota transplant (FMT) for most patients with recurrent Clostridioides difficile (C. diff) infection.

21 Feb 2024

New model pinpoints drug interactions in the digestive tract

Any drug that is taken orally must pass through the lining of the digestive tract. Transporter proteins found on cells that line the GI tract help with this process, but for many drugs, it's unknown which of those transporters they use to exit the digestive tract.

20 Feb 2024

Missing gut microbes after antibiotics and a high-fat diet may be to blame for sugar-free candy and gum giving you gas

A recent Cell study showed how a high-fat diet and antibiotic exposure could trigger sorbitol intolerance by depleting Clostridia from the gut microbiota.

20 Feb 2024

Discovery of novel enzyme family holds potential for antibiotic development

Researchers at Umeå University in Sweden, led by Professor Felipe Cava, have identified a new family of enzymes that creates a unique type of cross-linking between the building blocks of bacterial cell walls.

19 Feb 2024

Study reveals limitations of AI in early sepsis detection

Proprietary artificial intelligence software designed to be an early warning system for sepsis can’t differentiate high and low risk patients before they receive treatments, according to a new study from the University of Michigan.

15 Feb 2024

Novel synthetic antibiotic effective against drug-resistant bacteria

A new antibiotic created by Harvard researchers overcomes antimicrobial resistance mechanisms that have rendered many modern drugs ineffective and are driving a global public health crisis.

15 Feb 2024

Fluid-filled lung sac found to be the hub for virus-eating cells

Scientists have long thought of the fluid-filled sac around our lungs merely as a cushion from external damage. Turns out, it also houses potent virus-eating cells that rush into the lungs during flu infections.

14 Feb 2024

Hormonal steroids found to boost drug resistance in gonorrhea bacteria

Study uncovers how Neisseria gonorrhoeae, a major sexually transmitted infection pathogen, utilizes host-produced hormonal steroids to enhance its drug resistance and survival, revealing a complex interaction between bacterial resistance mechanisms and human hormonal environment.

13 Feb 2024

Oral azithromycin reduces maternal sepsis and healthcare costs in low-resource settings

Sepsis, a severe infection that can lead to tissue damage, organ failure, and death, is one of the top three causes of maternal deaths worldwide, according to the World Health Organization.

12 Feb 2024

IPIAD augments standard therapy for pancreatic ductal adenocarcinoma

A new research perspective was published in Oncoscience (Volume 11) on February 7, 2024, entitled, "IPIAD- an augmentation regimen added to standard treatment of pancreatic ductal adenocarcinoma using already-marketed repurposed drugs irbesartan, pyrimethamine, itraconazole, azithromycin, and dapsone."

9 Feb 2024

Fungicide resistance: A global threat to human, animal, and plant health

Fungi can cause disease in both humans, animals, and plants. Every year, 1.5 million people die from fungal infections, and fungal attacks in food crops threaten food production.

9 Feb 2024

CARB-X awards $1.8 million to Visby Medical to develop a portable rapid PCR test for gonorrhea

Combating Antibiotic-Resistant Bacteria Biopharmaceutical Accelerator (CARB-X) will award up to US$1.8 million to biotechnology company, Visby Medical, to develop a portable rapid polymerase chain reaction (PCR) diagnostic to detect the presence of the pathogen that causes gonorrhea, Neisseria gonorrhoeae (NG), and its susceptibility to ciprofloxacin, a former frontline oral antibiotic that can no longer treat resistant NG.

9 Feb 2024

Antibiotic News and Research

Further Reading

Gut microbial metabolite plays a role in exacerbating thrombosis

Research reveals bacteria's dynamic defense duo against phage viruses

Key link discovered between spread of antibiotic resistance genes and drug resistance evolution

Breakthrough discovery offers hope for reducing infections in cystic fibrosis patients

Maternal antibiotic use during childbirth tied to higher risk of autoimmune diseases in children

University College Dublin launches new Centre for One Health to solve global health challenges

Digital DNA melting analysis can be a faster and more reliable tool for pathogen detection

Mutation in E. coli bacteria linked to severe disease

AGA guideline endorses fecal microbiota transplant as treatment for recurrent C. diff infection

New model pinpoints drug interactions in the digestive tract

Missing gut microbes after antibiotics and a high-fat diet may be to blame for sugar-free candy and gum giving you gas

Discovery of novel enzyme family holds potential for antibiotic development

Study reveals limitations of AI in early sepsis detection

Novel synthetic antibiotic effective against drug-resistant bacteria

Fluid-filled lung sac found to be the hub for virus-eating cells

Hormonal steroids found to boost drug resistance in gonorrhea bacteria

Oral azithromycin reduces maternal sepsis and healthcare costs in low-resource settings

IPIAD augments standard therapy for pancreatic ductal adenocarcinoma

Fungicide resistance: A global threat to human, animal, and plant health

CARB-X awards $1.8 million to Visby Medical to develop a portable rapid PCR test for gonorrhea

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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