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Filgotinib offers new promise for managing Crohn’s disease

Filgotinib, a JAK1 preferential inhibitor, shows promise as an effective and well-tolerated maintenance therapy for Crohn's disease, achieving clinical and endoscopic remission in phase 3 trials. The findings highlight its potential as a novel therapeutic option for difficult-to-treat patients.

8 Dec 2024

New Marie Skłodowska-Curie Doctoral Network advances AI solutions for Parkinson’s disease

Neurological disorders are now the leading cause of disability worldwide. Parkinson's disease is the second most common neurodegenerative disorder, and case numbers are growing quickly.

6 Dec 2024

Antipsychotics linked to increased behavioral problems in nursing homes

A new study conducted by researchers at the University of Waterloo analyzed data from nearly 500,000 Canadian patients who lived in nursing homes across Canada between 2000 and 2022.

6 Dec 2024

Study: Brain volume changes correlate with social behavior differences in psychiatric conditions

A study published in Molecular Psychiatry found that brain volume changes correlate with social behavior differences in psychiatric conditions such as autism spectrum disorder and schizophrenia.

6 Dec 2024

Chikungunya's health and economic impact likely underestimated

This study assesses chikungunya's health and economic impacts, revealing significant burdens on health systems and a global cost of approximately $49.9 billion.

5 Dec 2024

Coral-inspired bone graft could transform treatment for bone defects

Researchers at Swansea University have developed a revolutionary bone graft substitute inspired by coral which not only promotes faster healing but dissolves naturally in the body after the repair is complete.

5 Dec 2024

Childhood diabetes rates surge globally

Researchers investigate global trends in childhood diabetes rates and different factors that contribute to its incidence.

4 Dec 2024

SRF awards $230,000 grant to advance research on SYNGAP1-Related Disorders

The SynGAP Research Fund (SRF) has awarded a $230,000 grant to The Jackson Laboratory Rare Disease Translational Center to characterize a mouse model for SYNGAP1-Related Disorders, (SRD), a severe neurodevelopmental disorder marked by seizures, intellectual disabilities, and motor and behavioral challenges.

4 Dec 2024

Mexican American women show highest rates of medication nonadherence after stroke

Women who have had a stroke may be less likely than men to take medications to prevent a second stroke, with Mexican American women reporting the highest rates of nonadherence, according to new research published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

4 Dec 2024

Advanced modeling unveils hidden costs of global chikungunya infection

The health and financial implications of the emerging threat of mosquito-borne chikungunya viral infection have most likely been significantly underestimated, with total costs probably approaching US$ 50 billion in 2011-20 alone, suggests a comprehensive data analysis, published in the open access journal BMJ Global Health.

4 Dec 2024

Minimally invasive procedure provides relief for knee osteoarthritis sufferers

A minimally invasive procedure provides significant relief from knee pain and may prevent the need for knee replacement surgery in people with osteoarthritis, according to a study being presented this week at the annual meeting of the Radiological Society of North America (RSNA).

3 Dec 2024

European leaders urged to develop action plan for rare diseases

The EESC high-level conference held in Budapest urged the new European Commission and the EU Member States to develop a comprehensive policy framework, setting common and measurable objectives to address the rare disease pathway and further increase European cooperation.

2 Dec 2024

UK’s hearing loss organizations address misleading claims about dementia

The UK’s leading hearing loss organizations have joined forces to highlight misleading reports by some health professionals and the media that hearing loss causes dementia, and treating hearing loss will reduce our individual risk of dementia.

2 Dec 2024

University of Arizona receives $1.7 million for spina bifida research

Researchers at the University of Arizona College of Medicine – Tucson received $1.7 million in funding from the Centers for Disease Control and Prevention to improve knowledge regarding the prevalence, mortality and health outcomes for people of all ages living with spina bifida.

2 Dec 2024