Fibrosis News and Research

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Fibrosis is the growth of fibrous tissue.

Discovery could pave the way for new approaches to treating chronic respiratory diseases

An international research team has discovered a new cell state in embryonic airway development that has been overlooked until now.

11 Apr 2023

Novel amino acid compound treats nonalcoholic fatty liver disease in non-human primates

A recently developed amino acid compound successfully treats nonalcoholic fatty liver disease in non-human primates - bringing scientists one step closer to the first human treatment for the condition that is rapidly increasing around the world, a study suggests.

10 Apr 2023

Does higher caffeine and coffee intake impact colonic microbiota composition and diversity?

Researchers investigated the association between caffeine and the colonic microbiome.

6 Apr 2023

Understanding how surface factors influence or inhibit biofilm formation in the presence of antibiotics

Similar to how cells within human tissues communicate and function together as a whole, bacteria are also able to communicate with each other through chemical signals, a behavior known as quorum signaling (QS).

5 Apr 2023

New imaging technique can improve the treatment of intestinal strictures in Crohn's disease

Patients suffering from Crohn's disease, a chronic inflammatory intestinal disorder, develop painful constrictions in the bowel.

5 Apr 2023

FUJIFILM Healthcare Corporation to release ARIETTA™ 750 DeepInsight™ ultrasound system

FUJIFILM Healthcare Corporation is set to release the ARIETTA 750 DeepInsight ultrasound system – a new AI-powered diagnostic ultrasound system with superior image quality – in April 2023.

From FUJIFILM Corporation 4 Apr 2023

Study assesses the cellular and molecular immunopathology of post-COVID lung disease

Researchers assessed the cellular and molecular level immunopathology of PCLD.

4 Apr 2023

Pathologic complete response can be used as a prognostic factor for clinical outcomes in soft tissue sarcoma patients

Combined long-term survival results from nonrandomized phase II trial NRG Oncology RTOG 0630 and the ancillary analysis of the combined NRG-RTOG 0630/9514 trials indicate that pathologic complete response (pCR) is associated with improved survival outcomes for patients with localized soft tissue sarcoma (STS) who receive preoperative chemoradiotherapy or radiotherapy.

31 Mar 2023

New therapeutic approach to eliminate aging cells by boosting anti-viral immune response

Aging, or senescent cells, which stop dividing but don't die, can accumulate in the body over the years and fuel chronic inflammation that contributes to conditions such as cancer and degenerative disorders.

30 Mar 2023

New type of nanoparticle can deliver messenger RNA encoding useful proteins to the lungs

Engineers at MIT and the University of Massachusetts Medical School have designed a new type of nanoparticle that can be administered to the lungs, where it can deliver messenger RNA encoding useful proteins.

30 Mar 2023

New research may upend long-held scientific dogma about short telomeres and cancer risk

Johns Hopkins Medicine scientists say their 20-year study of more than 200 people with premature aging syndromes caused by abnormally short telomeres, or shortened repetitive DNA sequences at the ends of chromosomes, may upend long-held scientific dogma and settle conflicting studies about how and whether short telomeres contribute to cancer risk.

30 Mar 2023

Advanced pancreatic cancer model more accurately depicts PDAC tumor progression

Pancreatic ductal adenocarcinoma (PDAC), is highly aggressive and lethal. It is the most prevalent type of pancreatic cancer, making up 90% of cases; it also has a high rate of metastasis, with an average five-year survival rate of less than 10%.

29 Mar 2023

NIH scientists discover an autoinflammatory disease caused by mutations in the LYN gene

Scientists have identified an autoinflammatory disease caused by mutations in the LYN gene, an important regulator of immune responses in health and disease.

28 Mar 2023

Understanding the structure of CFTR could help design more effective therapies for cystic fibrosis

Scientists at St. Jude Children's Research Hospital and Rockefeller University have combined their expertise to gain a better understanding of the cystic fibrosis transmembrane conductance regulator (CFTR).

23 Mar 2023

Researchers identify an enzyme associated with kidney fibrosis in both mice and humans

Researchers at Nagoya University in Japan have identified two enzymes that are involved in macrophage polarization, one of the key factors affecting fibrosis.

22 Mar 2023

Researchers discover how a single mechanosensitive protein induces fibrosis

Researchers from Kyushu University have found how a single mechanosensitive protein induces the process that thickens and scars tissue, known as fibrosis. The protein, called VGLL3, was shown to contribute to fibrosis in multiple organs.

22 Mar 2023

Animal studies show potential of new drug to curb painful hyperinflammation from osteoarthritis

A team of researchers at the Keck School of Medicine of USC have found a drug with the potential for curbing painful hyperinflammation from osteoarthritis, according to results of an animal study.

22 Mar 2023

Researchers discover how a mutation in the desmosomal gene leads to arrhythmogenic cardiomyopathy

Mutations in genes that form the desmosome are the most common cause of the cardiac disease arrhythmogenic cardiomyopathy (ACM), which affects one in 2000 to 5000 people worldwide.

22 Mar 2023

Green tea holds potential as treatment for uterine fibroids, PCOS, and menopausal symptoms

In a recent study published in the journal Nutrients, researchers at Johns Hopkins Medicine reviewed the beneficial properties of green tea in alleviating symptoms of benign gynecological disorders.

21 Mar 2023

£3 million funding to support the development of new antimicrobials for cystic fibrosis patients

Today (16 March 2023), Cystic Fibrosis (CF) Syndicate in Antimicrobial Resistance (AMR) announces a £3 million Collaborative Discovery Programme for drug discovery innovators to accelerate the development of new treatments for people with CF.

20 Mar 2023

Fibrosis News and Research

Further Reading

Discovery could pave the way for new approaches to treating chronic respiratory diseases

Novel amino acid compound treats nonalcoholic fatty liver disease in non-human primates

Does higher caffeine and coffee intake impact colonic microbiota composition and diversity?

Understanding how surface factors influence or inhibit biofilm formation in the presence of antibiotics

New imaging technique can improve the treatment of intestinal strictures in Crohn's disease

FUJIFILM Healthcare Corporation to release ARIETTA™ 750 DeepInsight™ ultrasound system

Study assesses the cellular and molecular immunopathology of post-COVID lung disease

Pathologic complete response can be used as a prognostic factor for clinical outcomes in soft tissue sarcoma patients

New therapeutic approach to eliminate aging cells by boosting anti-viral immune response

New type of nanoparticle can deliver messenger RNA encoding useful proteins to the lungs

New research may upend long-held scientific dogma about short telomeres and cancer risk

Advanced pancreatic cancer model more accurately depicts PDAC tumor progression

NIH scientists discover an autoinflammatory disease caused by mutations in the LYN gene

Understanding the structure of CFTR could help design more effective therapies for cystic fibrosis

Researchers identify an enzyme associated with kidney fibrosis in both mice and humans

Researchers discover how a single mechanosensitive protein induces fibrosis

Animal studies show potential of new drug to curb painful hyperinflammation from osteoarthritis

Researchers discover how a mutation in the desmosomal gene leads to arrhythmogenic cardiomyopathy

Green tea holds potential as treatment for uterine fibroids, PCOS, and menopausal symptoms

£3 million funding to support the development of new antimicrobials for cystic fibrosis patients

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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