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GIST researchers unravel coordination mechanism of base excision repair

A new study by researchers from the Gwangju Institute of Science and Technology in the Republic of Korea has revealed the mechanism of DNA repair by enzymes exonuclease III and polymerase I by utilizing single molecule fluorescence resonance energy transfer (smFRET)-enabled dynamic observation.

14 Sep 2021

Novel method enables 3D imaging of human organs with micrometer precision

Researchers at Umeå University, Sweden, now demonstrate a method by which specific cell types in human organs can be studied with micrometer precision.

13 Sep 2021

Researchers find a way to turn SARS-CoV-2’s virulence mechanism against itself

A recent study, currently available on the bioRxiv* preprint server, reveals that a specific region of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can be targeted by antisense oligonucleotides to potently inhibit viral replication, and consequently the development of coronavirus disease (COVID-19).

12 Sep 2021

Microscopy paired with AI leads to a fast, accurate, and cost-effective COVID-19 test

Beckman researchers paired microscopy with artificial intelligence to develop a COVID-19 test that's fast, accurate, and cost-effective. All we need to do is say "ahh."

12 Sep 2021

Study sheds light on neurologic symptoms caused by SARS-CoV-2 infection

Researchers in Australia and Finland have provided important insights into how infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19) – might affect nervous system circuitries and cause neurologic symptoms.

6 Sep 2021

Uppsala researchers find solution to long-standing biological search enigma

How the cell can mend broken DNA using another DNA copy as template has puzzled researchers for years. How is it possible to find the correct sequences in the busy interior of the cell? Researchers from Uppsala university have now discovered the solution; it is easier to find a rope than a ball if you are blindfolded.

1 Sep 2021

Researchers show how a protein molecular motor can 'constrict' cell membranes

Cells in the human body constantly receive substances from the outside via a process called endocytosis. One important endocytosis pathway involves the formation of a protrusion within the cell membrane, pointing to the inside of the cell, triggered when a molecule needing to get in reaches the membrane.

31 Aug 2021

HMGA1 plays role in gastric cancer cell proliferation and metastasis

Aging-US published "HMGA1 promotes gastric cancer growth and metastasis by transactivating SUZ12 and CCDC43 expression" which reported that HMGA1 is overexpressed in GC cells and the high expression of HMGA1 was correlated with worse survival in GC patients using a bioinformatics assay.

19 Aug 2021

Study reveals mechanism behind male infertility caused by autoimmune disease

Investigators have found that the absence of autoimmune regulator (Aire) in mice results in fertility problems similar to those affecting men with autoimmune polyendocrine syndrome type I (APS-1).

19 Aug 2021

University of Arkansas receives $6.1 million grant to establish an institute focused on virus research

The National Science Foundation has awarded a $6.1 million grant to the University of Arkansas to establish a research institute focused on virology and virus ecology.

17 Aug 2021

Nitrogen-doped fluorescent carbon dots for detecting iodide ion, curcumin in biological and food samples

The ability to reliably and accurately detect levels of iodide ion and curcumin is crucial in the fields of food and life sciences.

16 Aug 2021

Discovery of highly potent neutralizing monoclonal antibodies against SARS-CoV-2

A new study published in the journal Nature Communications has reported two neutralizing antibodies, namely, nCoVmab1 and nCoVmab2, which are potent against SARS-CoV-2.

13 Aug 2021

Optical nanoscopy reveals how SARS-CoV-2 infection alters human airway cells

How do viruses reorganize host cells with spatial and molecular specificity? Researchers from the Netherlands provided new insights in a recent study posted to the bioRxiv* preprint server, where they use optical nanoscopy to look at severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-triggered changes in primary human airway cells.

12 Aug 2021

Scientists develop new approach to identify proteins in the living brain

For the first time, researchers have developed a successful approach for identifying proteins inside different types of neurons in the brain of a living animal.

11 Aug 2021

Microbe transmitted between mosquitoes could be key to controlling malaria

A microbe that is transmitted between male and female mosquitoes but can also block reproduction could be key to controlling malaria by targeting its release into mosquito populations, a study says.

10 Aug 2021

Antiviral activity of lipid-modified remdesivir in comparison to common remdesivir

In new research, scientists evaluated the broad-spectrum antiviral activity of ODBG-P-RVn, an orally available, lipid-modified monophosphate prodrug of the remdesivir parent nucleoside (GS-441524) against viruses that cause diseases of human public health concern, including SARS-CoV-2.

10 Aug 2021

New cargo-carrying nanocontainer constructed entirely from biological components

Nanocontainers can transport substances into cells where they can then take effect. This is the method used in, for example, the mRNA vaccines currently being employed against Covid-19 as well as certain cancer drugs.

6 Aug 2021

New method for producing pseudotyped virus particles bearing spike protein of SARS-CoV-2

A new study discusses the development of an improved protocol based on cell lines that can consistently express S proteins.

5 Aug 2021

Using two different CRISPR enzymes to develop a faster and easier COVID-19 diagnostic test

Frequent, rapid testing for COVID-19 is critical to controlling the spread of outbreaks, especially as new, more transmissible variants emerge.

5 Aug 2021

Rigaku Acquires Life Science Imaging Equipment Manufacturer MILabs

Rigaku Corporation (Headquarters: Akishima-shi, Tokyo; President: Toshiyuki Ikeda; "Rigaku"), a leading manufacturer of X-ray analysis equipment, has acquired all issued shares of MILabs B.V. (Headquarters: Houten, The Netherlands; CEO and CSO: Dr. Frederik Beekman; “MILabs”)

From Rigaku Corporation 4 Aug 2021